scholarly journals GW28-e0649 The Six-Minute Walk Distance in Healthy Subjects Aged 20–30 Years: A Pilot Study

2017 ◽  
Vol 70 (16) ◽  
pp. C164
Author(s):  
Yafei Wang ◽  
Yu Gao
2006 ◽  
Vol 100 (4) ◽  
pp. 658-665 ◽  
Author(s):  
Bernadine Camarri ◽  
Peter R. Eastwood ◽  
Nola M. Cecins ◽  
Philip J. Thompson ◽  
Sue Jenkins

2021 ◽  
Vol 11 (8) ◽  
pp. 48-60
Author(s):  
Dolly Shah ◽  
Anjali Bhise

Title: Effect of Pulmonary Rehabilitation Training in Non-, Ex- and Current Smokers with Chronic Respiratory Disorders by the measurement of Functional Capacity: A Pilot Study Background: Earlier research shows efficacy of pulmonary rehabilitation in chronic lung disorders with regards to their smoking status, but not in all 3 groups together (i.e. Ex-,Never- and Current smokers). So, the goal is to find out effectiveness of pulmonary rehabilitation in chronic lung disorders with regard to their smoking status by the measurement of 6 minute walk distance. This study will help in identifying least benefited to most benefited group among 3 groups by pulmonary rehabilitation . Methodology : Total 15 patients of both gender and age 30-80 years were randomly selected and divided into 3 groups: Non-, Ex- and Current Smokers with Chronic Respiratory Disorders. Pulmonary Rehabilitation was given for 8 weeks, 3 times / week (30-40 minutes). Pre and Post PR (After 8 weeks), functional capacity was measured by 6 minute walk distance. Data was analyzed by SPSS (v16.0) - One way ANOVA to compare 3 groups and Post Hoc tests to detect the intergroup differences . Results: Pulmonary Rehabilitation was effective in all 3 groups and Functional Capacity of all patients was improved (p<0.05). Effectiveness of Pulmonary Rehabilitation was more in Non- Smokers compared to Current Smokers. (p<0.05) Conclusion: Effectiveness of Pulmonary Rehabilitation was significant in all smokers with chronic respiratory disorders but Non- Smokers were more benefited from Current Smokers due to their non-smoking status. These findings emphasized effectiveness of Pulmonary Rehabilitation and benefits of non-smoking status among patients with chronic respiratory disorders. So, we must encourage measures for smoking cessation at earliest in pulmonary rehabilitation program . Key words: Functional Capacity, 6 Minute Walk Distance, Pulmonary Rehabilitation, Smokers.


2022 ◽  
pp. 1358863X2110688
Author(s):  
Dereck L Salisbury ◽  
Kari Swanson ◽  
Rebecca JL Brown ◽  
Diane Treat-Jacobson

Background: Treadmill walking is the most commonly recommended exercise modality in supervised exercise therapy (SET) for peripheral artery disease (PAD); however, other modalities may be equally effective and more tolerable for patients. The primary aim of this single-blind, randomized pilot study was to compare the feasibility, safety, and preliminary efficacy of a treadmill walking (TM) versus a total body recumbent stepping (TBRS) exercise program for treatment of PAD. Methods: Participants ( n = 19) enrolled in a 12-week SET program and were randomized to either a TM ( n = 9) or TBRS ( n = 10) exercise group that followed current SET exercise guidelines. Feasibility, safety, and efficacy outcomes were assessed. Results: SET attendance was 86% and 71%, respectively, for TBRS and TM groups ( p = 0.07). Session exercise dose (metabolic equivalents of task [MET] minutes) (mean [SD]) for TM was 117.6 [27.4] compared to 144.7 [28.7] in the TBRS group ( p = 0.08). Study-related adverse events were nine in 236 training hours and three in 180 training hours for the TBRS and TM groups, respectively. There were no significant differences between groups for improvement in 6-minute walk distance (mean [SD]) (TM: 133.2 ft [53.5] vs TBRS: 154.8 ft [49.8]; p = 0.77) after adjusting for baseline 6-minute walk distance. Conclusion: This is the first randomized study comparing TBRS to TM exercise in SET using current SET guidelines. This pilot study showed that TBRS is a feasible and safe exercise modality in SET. This study provides preliminary efficacy of the use of TBRS exercise in SET programs following current guidelines. Larger studies should be conducted to confirm these findings.


2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
C Deaton ◽  
F Forsyth ◽  
J Mant ◽  
D Edwards ◽  
R Hobbs ◽  
...  

Abstract Aims Patients with heart failure with preserved ejection fraction (HFpEF) are usually older and multi-morbid and diagnosis can be challenging. The aims of this cohort study were to confirm diagnosis of HFpEF in patients with possible HFpEF recruited from primary care, to compare characteristics and health status between those with and without HFpEF, and to determine factors associated with health status in patients with HFpEF. Methods Patients with presumed HFpEF were recruited from primary care practices and underwent clinical assessment and diagnostic evaluation as part of a longitudinal cohort study. Health status was measured by Montreal Cognitive Assessment (MOCA), 6-minute walk test, symptoms, and the Kansas City Cardiomyopathy Questionnaire (KCCQ), and quality of life (QoL) by EQ-5D-5L visual analogue scale (VAS). Results 151 patients (mean age 78.5±8.6 years, 40% women, mean EF 56% + 9.4) were recruited and 93 (61.6%) were confirmed HFpEF (those without HFpEF had other HF and cardiac diagnoses). Patients with and without HFpEF did not differ by age, MOCA, blood pressure, heart rate, NYHA class, proportion with atrial fibrillation, Charlson Comorbidity Index, or NT-ProBNP levels. Patients with HFpEF were more likely to be women, overweight or obese, frail, and to be more functionally impaired by 6 minute walk distance and gait speed than those without. Although not statistically significant, patients with HFpEF had clinically significant differences (&gt;5 points) on the physical limitations, symptom burden and clinical summary subscales of the KCCQ, but did not differ by other subscales or by EQ-5D-5L VAS (70±17 vs 73±19, p=0.385). More patients with HFpEF reported daytime dyspnoea (63% vs 46%, p=0.035) and fatigue (81% vs 61%, p=0.008), but not other symptoms compared to those without HFpEF. For both groups BMI was moderately negatively correlated with KCCQ subscale scores, and 6 minute walk distance was positively correlated with KCCQ subscales. Conclusions Nearly 40% were not confirmed as HFpEF indicating the challenges of diagnosis. Patients with confirmed HFpEF differed by sex, overweight/obesity, frailty, functional impairment, and symptoms but not by age or comorbidities from those without HFpEF. These differences were reflected in some subscale scores of the KCCQ, but not how patients reported their quality of life on the KCCQ QoL subscale and EQ-5D-5L VAS. Older patients with HFpEF reported relatively high QoL despite poor health status by functional impairment, frailty and symptoms. Funding Acknowledgement Type of funding source: Public grant(s) – National budget only. Main funding source(s): National Institute of Health Research School of Primary Care Research


Pulmonology ◽  
2021 ◽  
Author(s):  
Alyson W. Wong ◽  
Stephanie López-Romero ◽  
Esperanza Figueroa-Hurtado ◽  
Saul Vazquez-Lopez ◽  
Kathryn M. Milne ◽  
...  

2021 ◽  
Vol 50 (Supplement_1) ◽  
pp. i12-i42
Author(s):  
R R Chungath ◽  
M D Witham ◽  
C L Clarke ◽  
A Hutcheon ◽  
S Gandy ◽  
...  

Abstract Background Mitochondrial dysfunction has been proposed as a therapeutic target to improve muscle strength and endurance, but the contribution that mitochondrial dysfunction makes to impaired skeletal muscle performance in older people remains unclear. We studied the relationship between phosphocreatine recovery rate (a measure of skeletal muscle mitochondrial function) and physical performance in older people. Methods We analysed data from the Allopurinol in Functional Impairment (ALFIE) trial. Participants aged 65 and over, who were unable to walk 400 m in six minutes, underwent 31P magnetic resonance spectroscopy of the calf after exercise at baseline and at 20 weeks follow up. The phosphocreatine recovery half-life time (t-half) was derived as a measure of mitochondrial function. Participants also undertook the 6-minute walk distance, the Short Physical Performance Battery test (SPPB), and had muscle mass measured using bio-impedance analysis. Bivariate correlations and multivariable regression analyses were conducted to determine associations between t-half and baseline factors. Results One hundred and seventeen people underwent baseline 31P magnetic resonance spectroscopy, mean age 80.4 years (SD 6.0); 56 (48%) were female. Mean 6-minute walk was 291 m (SD 80) and mean SPPB score was 8.4 (SD 1.9). T-half was significantly correlated with SPPB score (r = 0.22, p = 0.02) but not with 6-minute walk distance (r = 0.10, p = 0.29). In multivariable linear regression, muscle mass and weight, but not t-half, were independently associated with SPPB score and with 6-minute walk distance. The change in t-half between baseline and 20 weeks was not significantly associated with the change in SPPB (r = 0.03, p = 0.79) or with the change in 6-minute walk distance (r = −0.11, p = 0.28). Conclusion Muscle mass, but not phosphocreatine recovery time, was associated with Short Physical Performance Battery score and 6-minute walk distance in this cohort of older people with functional impairment.


2010 ◽  
Vol 11 (1) ◽  
pp. 25-30 ◽  
Author(s):  
Neiko Ozasa ◽  
Takeshi Morimoto ◽  
Yutaka Furukawa ◽  
Hiroshi Hamazaki ◽  
Toru Kita ◽  
...  

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