Atopic dermatitis is associated with an increased risk for rheumatoid arthritis and inflammatory bowel disease, and a decreased risk for type 1 diabetes

2016 ◽  
Vol 137 (1) ◽  
pp. 130-136 ◽  
Author(s):  
Jochen Schmitt ◽  
Kristin Schwarz ◽  
Hansjörg Baurecht ◽  
Melanie Hotze ◽  
Regina Fölster-Holst ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Inflammatory Bowel Disease ◽  
Type 1 Diabetes ◽  
Atopic Dermatitis ◽  
Bowel Disease ◽  
Increased Risk ◽  
Inflammatory Bowel

scholarly journals Solar Radiation and Vitamin D: Mitigating Environmental Factors in Autoimmune Disease

2012 ◽  
Vol 2012 ◽  
pp. 1-9 ◽  
Author(s):  
Gerry K. Schwalfenberg
Keyword(s):  
Rheumatoid Arthritis ◽  
Multiple Sclerosis ◽  
Inflammatory Bowel Disease ◽  
Vitamin D ◽  
Type 1 Diabetes ◽  
Autoimmune Disease ◽  
Solar Radiation ◽  
Inflammatory Bowel

This paper looks at the environmental role of vitamin D and solar radiation as risk reduction factors in autoimmune disease. Five diseases are considered: multiple sclerosis, type 1 diabetes, rheumatoid arthritis, autoimmune disease of the thyroid, and inflammatory bowel disease. Clinical relevant studies and factors that may indicate evidence that autoimmune disease is a vitamin D-sensitive disease are presented. Studies that have resulted in prevention or amelioration of some autoimmune disease are discussed. An example of the utility of supplementing vitamin D in an unusual autoimmune disease, idiopathic thrombocytic purpura, is presented.

scholarly journals Comparative genetic analysis of inflammatory bowel disease and type 1 diabetes implicates multiple loci with opposite effects

2010 ◽  
Vol 19 (10) ◽  
pp. 2059-2067 ◽  
Author(s):  
Kai Wang ◽  
Robert Baldassano ◽  
Haitao Zhang ◽  
Hui-Qi Qu ◽  
Marcin Imielinski ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Type 1 Diabetes ◽  
Genetic Analysis ◽  
Bowel Disease ◽  
Multiple Loci ◽  
Inflammatory Bowel ◽  
Comparative Genetic Analysis

scholarly journals The Risk of Rheumatoid Arthritis among Patients with Inflammatory Bowel Disease: A Systematic Review and Meta-analysis

2020 ◽  
Author(s):  
Yi Chen ◽  
Lang Chen ◽  
Changsheng Xing ◽  
Guangtong Deng ◽  
Furong Zeng ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Inflammatory Bowel Disease ◽  
Cohort Studies ◽  
Bowel Disease ◽  
Meta Analysis ◽  
Sensitivity Analyses ◽  
Cross Sectional ◽  
Relative Risks ◽  
Increased Risk ◽  
Inflammatory Bowel

Abstract Background: Studies have suggested that patients with inflammatory bowel disease (IBD) have an increased risk of rheumatoid arthritis (RA). However, the available data on this association are inconsistent. This meta-analysis aimed to determine the association between IBD and the risk of RA. Methods: Observational studies investigating the RA risk among patients with IBD (Crohn disease (CD) and/or ulcerative colitis (UC)) were searched in PubMed, Embase, and Web of Science from the date of inception to December 2019 . The methodological quality of the included studies was assessed using the Newcastle-Ottawa Scale. Relative risks (RRs) and corresponding 95% confidential intervals (CIs) were pooled with a random-effects model. Heterogeneity was evaluated using I 2 statistics while publication bias was determined using Begg’s and Egger’s tests. Subgroup and sensitivity analyses were performed. Results: A total of three cohort studies, three cross-sectional studies, and two case-control study were included in the meta-analyses. Compared to the non-IBD control or general population, there was a significantly higher risk of RA among patients with IBD (RR=2.59; 95% CI: 1.93–3.48). Moreover, both CD (RR=3.14; 95% CI: 2.46–4.01) and UC (RR=2.29; 95% CI: 1.76–2.97) were associated with a significantly increased risk of RA . However, heterogeneity was substantial across studies and the subgroup analyses failed to identify the potential source of heterogeneity. Conclusions: Patients with IBD have a greater risk of developing RA. Rheumatologists should be consulted when patients with IBD present with undifferentiated joint complaints. However, more prospective cohort studies are needed to validate these results.

Inflammatory bowel disease is more common in type 1 diabetes mellitus

Gut ◽  
2011 ◽  
Vol 60 (Suppl 1) ◽  
pp. A208-A208 ◽  
Author(s):  
J. S. Leeds ◽  
A. D. Hopper ◽  
M. Hadjivassiliou ◽  
S. Tesfaye ◽  
D. S. Sanders
Keyword(s):  
Diabetes Mellitus ◽  
Inflammatory Bowel Disease ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Bowel Disease ◽  
Inflammatory Bowel

scholarly journals Comorbidity of inflammatory bowel disease in children and adolescents with type 1 diabetes

2020 ◽  
Author(s):  
Hildegard Jasser‐Nitsche ◽  
Susanne Bechtold‐Dalla Pozza ◽  
Elisabeth Binder ◽  
Esther Bollow ◽  
Bettina Heidtmann ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Type 1 Diabetes ◽  
Children And Adolescents ◽  
Bowel Disease ◽  
Inflammatory Bowel

scholarly journals Influence of host immunoregulatory genes, ER stress and gut microbiota on the shared pathogenesis of inflammatory bowel disease and Type 1 diabetes

Immunotherapy ◽  
2013 ◽  
Vol 5 (12) ◽  
pp. 1357-1366 ◽  
Author(s):  
Altin Gjymishka ◽  
Roxana M Coman ◽  
Todd M Brusko ◽  
Sarah C Glover
Keyword(s):  
Inflammatory Bowel Disease ◽  
Type 1 Diabetes ◽  
Gut Microbiota ◽  
Er Stress ◽  
Bowel Disease ◽  
Inflammatory Bowel
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