Oral Antibiotic Bowel Prep Significantly Reduces Surgical Site Infection Rates and Readmission Rates in Elective Colorectal Surgery

2014 ◽  
Vol 219 (3) ◽  
pp. S18-S19 ◽  
Author(s):  
Melanie S. Morris ◽  
Laura A. Graham ◽  
Martin J. Heslin ◽  
John D. Hunter ◽  
Jamie A. Cannon ◽  
...  
Keyword(s):  
Colorectal Surgery ◽  
Surgical Site Infection ◽  
Oral Antibiotic ◽  
Site Infection ◽  
Infection Rates ◽  
Readmission Rates ◽  
Elective Colorectal Surgery ◽  
Bowel Prep

scholarly journals Oral Antibiotic Prophylaxis Lowers Surgical Site Infection in Elective Colorectal Surgery: Results of a Pragmatic Cohort Study in Catalonia

2021 ◽  
Vol 10 (23) ◽  
pp. 5636
Author(s):  
Josep M. Badia ◽  
Miriam Flores-Yelamos ◽  
Ana Vázquez ◽  
Nares Arroyo-García ◽  
Mireia Puig-Asensio ◽  
...  
Keyword(s):  
Cohort Study ◽  
Colorectal Surgery ◽  
Surgical Site Infection ◽  
Antibiotic Prophylaxis ◽  
Univariate Analysis ◽  
Oral Antibiotic ◽  
Site Infection ◽  
Baseline Phase ◽  
Elective Colorectal Surgery ◽  
Oral Antibiotic Prophylaxis

Background: The role of oral antibiotic prophylaxis (OAP) and mechanical bowel preparation (MBP) in the prevention of surgical site infection (SSI) after colorectal surgery is still controversial. The aim of this study was to analyze the effect of a bundle including both measures in a National Infection Surveillance Network in Catalonia. Methods: Pragmatic cohort study to assess the effect of OAP and MBP in reducing SSI rate in 65 hospitals, comparing baseline phase (BP: 2007–2015) with implementation phase (IP: 2016–2019). To compare the results, a logistic regression model was established. Results: Out of 34,421 colorectal operations, 5180 had SSIs (15.05%). Overall SSI rate decreased from 18.81% to 11.10% in BP and IP, respectively (OR 0.539, CI95 0.507–0.573, p < 0.0001). Information about bundle implementation was complete in 61.7% of cases. In a univariate analysis, OAP and MBP were independent factors in decreasing overall SSI, with OR 0.555, CI95 0.483–0.638, and OR 0.686, CI95 0.589–0.798, respectively; and similarly, organ/space SSI (O/S-SSI) (OR 0.592, CI95 0.494–0.710, and OR 0.771, CI95 0.630–0.944, respectively). However, only OAP retained its protective effect at both levels at multivariate analyses. Conclusions: oral antibiotic prophylaxis decreased the rates of SSI and O/S-SSI in a large series of elective colorectal surgery.

Prospective Surveillance Effectively Reduced Rates of Surgical Site Infection Associated With Elective Colorectal Surgery at a University Hospital in Japan

2006 ◽  
Vol 27 (5) ◽  
pp. 526-528 ◽  
Author(s):  
Tsuyoshi Konishi ◽  
Toshiaki Watanabe ◽  
Keita Morikane ◽  
Kazuhiko Fukatsu ◽  
Joji Kitayama ◽  
...  
Keyword(s):  
Colorectal Surgery ◽  
Surgical Site Infection ◽  
University Hospital ◽  
Site Infection ◽  
Prospective Surveillance ◽  
Elective Colorectal Surgery ◽  
Nationwide Surveillance ◽  
Surveillance Database

At a university hospital in Japan, the introduction of prospective surveillance and subsequent interventions was effective in reducing the rate of surgical site infection associated with elective colorectal surgery from 27.5% to 17.8% of surgeries. Japan should both recognize the importance of broader surveillance for surgical site infection and establish its own nationwide surveillance database.

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