Development of a fully automated on-line solid phase extraction and high-performance liquid chromatography with diode array detection method for the pharmacokinetic evaluation of bavachinin: A study on absolute bioavailability and dose proportionality

2012 ◽  
Vol 893-894 ◽  
pp. 21-28 ◽  
Author(s):  
Lei Liu ◽  
Kang-Ning Liu ◽  
Ya-Bin Wen ◽  
Han-Wen Zhang ◽  
Ya-Xin Lu ◽  
...  
Keyword(s):  
High Performance ◽  
Detection Method ◽  
Solid Phase ◽  
Dose Proportionality ◽  
Absolute Bioavailability ◽  
Diode Array ◽  
Diode Array Detection ◽  
On Line ◽  
Array Detection ◽  
Pharmacokinetic Evaluation

A novel HPLC method for the determination of zonisamide in human plasma using microextraction by packed sorbent optimised by experimental design

2017 ◽  
Vol 9 (40) ◽  
pp. 5910-5919 ◽  
Author(s):  
Dina Lourenço ◽  
Mafalda Sarraguça ◽  
Gilberto Alves ◽  
Paula Coutinho ◽  
André R. T. S. Araujo ◽  
...  
Keyword(s):  
Human Plasma ◽  
High Performance ◽  
Detection Method ◽  
Hplc Method ◽  
Diode Array ◽  
Diode Array Detection ◽  
Microextraction By Packed Sorbent ◽  
Array Detection ◽  
Packed Sorbent

A novel high-performance liquid chromatography-diode array detection method based on microextraction by packed sorbent as a sample preparation approach was developed and validated for the determination of zonisamide in human plasma.

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