scholarly journals Two-Year Follow-Up OCT Images of 2 Bifurcation Lesions Treated With Bioresorbable Vascular Scaffolds

2015 ◽  
Vol 8 (5) ◽  
pp. 617-618 ◽  
Author(s):  
Hiroyoshi Kawamoto ◽  
Vasileios F. Panoulas ◽  
Katsumasa Sato ◽  
Tadashi Miyazaki ◽  
Azeem Latib ◽  
...  
Keyword(s):  
Vascular Scaffolds ◽  
Bioresorbable Vascular Scaffolds ◽  
Bifurcation Lesions

scholarly journals The impact of the use of bioresorbable vascular scaffolds and drug-coated balloons in coronary bifurcation lesions

2019 ◽  
Vol 71 (1) ◽  
Author(s):  
Mostafa Elwany ◽  
Amr Zaki ◽  
Azeem Latib ◽  
Luca Testa ◽  
Alfonso Ielasi ◽  
...  
Keyword(s):  
Study Endpoint ◽  
Primary Study ◽  
Coronary Bifurcation ◽  
Coronary Bifurcation Lesions ◽  
Main Vessel ◽  
Vascular Scaffolds ◽  
Bioresorbable Vascular Scaffolds ◽  
Bifurcation Lesions ◽  
The Impact

Abstract Background Despite the improvement in techniques and tools, coronary lesions involving a bifurcation are still challenging and the outcome with drug-eluting stents is not always optimal. The role of bioresorbable vascular scaffolds (BVS) and drug-coated balloons (DCB) in this setting has not been adequately investigated yet. Results From the databases of 6 italian centers with high proficiencies in newer technologies, we retrospectively collected all consecutive cases of coronary bifurcations managed or attempted with the implantation of at least one BVS in the main vessel and the use of one DCB in the side branch (SB). Primary study endpoint was the occurrence of major adverse cardiovascular events (MACE) at the longest available follow-up. Fourty patients fulfilled the enrollment criterion, 22.5% had diabetes and 50% an acute coronary syndrome. Average syntax score was 15.04 ± 7.18, all lesions were de novo, and 27 patients (67.5%) had a type 1,1,1 Medina lesion. Twenty-three lesions (57.5%) involved the proximal left anterior-descending artery/first diagonal branch. Only 32.5% of patients underwent an intravascular imaging-guided angioplasty. Average lesion length was 21.4 mm in the main vessel and 11.49 mm in the SB. MV was always predilated and BVS received a postdilation in 100% of the cases. In 42.5% of the cases, the DCB was used during final kissing balloon inflation, and in no cases, a stent/BVS was required in the SB. Procedural success was achieved in 100% of the cases. After an average follow-up of 15.5 (± 11.5) months, we observed no MACE with only one case of target vessel revasularization (2.5%). Conclusions Management of coronary bifurcation lesions with the use of newer technologies including BVS and DCB seems feasible and effective at mid-term and long-term clinical follow-up.

scholarly journals Long-term clinical outcomes for bifurcation treatment using a provisional T-stenting and double proximal optimization technique with Absorb bioresorbable scaffolds

2017 ◽  
Vol 21 (1) ◽  
pp. 50
Author(s):  
R. D. Ivanchenko ◽  
A. V. Birukov ◽  
K. A. Smirnov
Keyword(s):  
Coronary Artery ◽  
Conflict Of Interest ◽  
Optimization Technique ◽  
Drug Eluting Stent ◽  
Long Term Follow Up ◽  
Vascular Scaffolds ◽  
Bioresorbable Vascular Scaffolds ◽  
Bifurcation Lesions

<p><strong>Aim.</strong> The article presents long-term outcomes of treatment of coronary artery bifurcation lesions by using bioresorbable vascular scaffolds and provisional T-stenting combined with double proximal optimization. <br /><strong>Methods.</strong> 14 patients aged 44-80 years (mean age 61±6 years) including 8 (57.14 %) males underwent endovascular treatment of coronary artery bifurcation lesions by using Absorb bioresorbable vascular scaffolds (BVS). Clinical/instrumental analysis was carried out after 23.7±4.12 months. Angiographic examination was performed in 12 cases (85.71 %). 7 patients (50 %) underwent optical coherent tomography. <br /><strong>Results.</strong> 11 patients (78.57) were free of angina during long-term follow-up. 1 patient (7.14 %) developed BVS thrombosis and received a drug-eluting stent. A neointimal layer of the main branch increased during long-term follow-up to 29.23±7.82%, that of the lateral branch – up to 19.2±7.48%. Optical coherence tomography (OCT) shows that all strata are fully covered with neointima, the number of strata with malappositions is minimal and the loss of the main branch diameter (16.9±4.9%) is insignificant. <br /><strong>Conclusion.</strong> The use of Absorb bioresorbable vascular scaffolds implanted by means of provisional T-stenting combined with double proximal optimization when treating coronary artery bifurcation lesions is a safe and efficient procedure.</p><p>Received 2 February 2017. Accepted 10 March 2017.</p><p><strong>Financing:</strong> The study did not have sponsorship.<br /><strong>Conflict of interest:</strong> The authors declare no conflict of interest.</p>

scholarly journals TCT-519 Feasibility and performance of everolimus-eluting bioresorbable vascular scaffolds (BVS) in long lesions (>25 mm): all-comers absorb registry with mid-term follow-up

2015 ◽  
Vol 66 (15) ◽  
pp. B212
Author(s):  
Santiago J. Camacho Freire ◽  
Jessica Roa-Garrido ◽  
Rosa M. Cardenal ◽  
Antonio Gomez Menchero ◽  
Javier Leon Jimenez ◽  
...  
Keyword(s):  
Vascular Scaffolds ◽  
Bioresorbable Vascular Scaffolds ◽  
And Performance

scholarly journals P1823 Feasibility of CCTA in assessment of luminal changes and coronary shear stress evolution after implantation of bioresorbable vascular scaffolds

2020 ◽  
Vol 21 (Supplement_1) ◽  
Author(s):  
D R Cernica ◽  
I Ferent ◽  
A Mester ◽  
D Opincariu ◽  
R Hodas ◽  
...  
Keyword(s):  
Shear Stress ◽  
Distal Part ◽  
Coronary Intervention ◽  
Visual Evaluation ◽  
Minimal Lumen Area ◽  
Vascular Scaffolds ◽  
Bioresorbable Vascular Scaffolds ◽  
Group 2 ◽  
Group 1

Abstract Funding Acknowledgements PlaqueImage - financed by the National Authority of Scientific Research and Innovation and the Romanian Ministry of European Funding Background Coronary shear stress (CSS) is a well-established local mechanical factor in atherogenesis, progression and destabilization of atherosclerotic plaques. Analysis of CSS after coronary stent placement is still lacking of large clinical studies. Purpose: The aim of this study was to: (1) test the feasibility of Coronary Computed Tomography Angiography (CCTA) for assessment of local hemodynamic and luminal changes after implantation of bioresorbable vascular scaffolds (BVS), and (2) to investigate CSS modifications after BVS implantation. Methods: We conducted a single center, prospective pilot study on 73 patients with coronary artery disease who underwent elective percutaneous coronary intervention (PCI); group 1 (n = 30) – patients with BVS and group 2 (n = 43) – patients with bare metal stent (BMS) implanted. CCTA scanning was performed in all patients prior PCI and at 12 months after PCI. The mean CSS at proximal and at distal part of the stented segment and at the level of the minimal lumen area (MLA) was calculated at baseline and at 12 months after BVS placement. Results: CCTA revealed a higher incidence of severe coronary stenosis in group 1 (73%) than in group 2 (30%) (p &lt; 0.0001). Sensibility of visual evaluation for identification of in-stent restenosis on CCTA was increased in BVS group (94%) than in BMS group (76.19%) (p = 0.0006), hence the group 1 had lower incidence of non-diagnostic evaluations. Mean CSS at the stented site was significantly lower at 12 months (1.9 +/- 0.68 Pa) that average CSS at baseline (2.87 +/- 3.08 Pa) (p = 0.0001). CSS analysis showed also a significantly decreased values at proximal level from 3.39 +/- 1.93 Pa at baseline to 1.91 +/- 0.68 Pa at follow up (p &lt; 0.0001), but not a significant decrease at distal part – 1.3+/-0.72 Pa at baseline and 1.59 +/- 0.65 Pa at 12 months follow up (p = 0.9). Conclusions: CCTA is a feasible technique for assessment of luminal changes following BVS implantation. BVS implantation contribute to the improvement of local hemodynamics by restoring physiological pattern of coronary flow, as demonstrated by the computational fluid hemodynamics assessment of coronary circulation.

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