Viral load and inflammatory cytokine dynamics associated with the prognosis of severe fever with thrombocytopenia syndrome virus infection: An autopsy case

2019 ◽  
Vol 25 (6) ◽  
pp. 480-484 ◽  
Author(s):  
Shigeki Nakamura ◽  
Naoki Iwanaga ◽  
Shintaro Hara ◽  
Satoshi Shimada ◽  
Yukio Kashima ◽  
...  
Keyword(s):  
Viral Load ◽  
Virus Infection ◽  
Inflammatory Cytokine ◽  
Autopsy Case ◽  
Severe Fever

scholarly journals Utility of the Cobas® Plasma Separation Card as a Sample Collection Device for Serological and Virological Diagnosis of Hepatitis C Virus Infection

Diagnostics ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 473
Author(s):  
Fernando Velásquez-Orozco ◽  
Ariadna Rando-Segura ◽  
Joan Martínez-Camprecios ◽  
Paula Salmeron ◽  
Adrián Najarro-Centeno ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Viral Load ◽  
Hepatitis C ◽  
Virus Infection ◽  
Hepatitis C Virus Infection ◽  
Sample Collection ◽  
Serum Samples ◽  
Plasma Separation ◽  
Virological Diagnosis ◽  
A Prospective Study

Diagnosis and clinical management of people infected with hepatitis C virus (HCV) relies on results from a combination of serological and virological tests. The aim of this study was to compare the performance of dried plasma spots (DPS), prepared using the cobas® Plasma Separation Card (PSC), to plasma and serum from venipuncture, for HCV diagnosis. We carried out a prospective study using DPS and paired plasma or serum samples. Serum and DPS samples were analyzed by immunoassay using Elecsys® Anti-HCV II (Roche). Plasma and DPS samples were analyzed using the cobas® HCV viral load and cobas® HCV genotyping tests (Roche). All DPS samples that had high anti-HCV antibody titers in serum were also antibody-positive, as were five of eight samples with moderate titers. Eight samples with low titers in serum were negative with DPS. Among 80 samples with plasma HCV viral loads between 61.5 and 2.2 × 108 IU/mL, 74 were RNA-positive in DPS. The mean viral load difference between plasma and DPS was 2.65 log10 IU/mL. The performance of DPS for detection of serological and virological markers of hepatitis C virus infection was comparable to that of the conventional specimen types. However, the limits of detection were higher for DPS.

Activation of platelet-derived growth factor receptor β in the severe fever with thrombocytopenia syndrome virus infection

2020 ◽  
Vol 182 ◽  
pp. 104926
Author(s):  
Hideki Tani ◽  
Miyuki Kimura ◽  
Hiroshi Yamada ◽  
Hikaru Fujii ◽  
Satoshi Taniguchi ◽  
...  
Keyword(s):  
Growth Factor ◽  
Virus Infection ◽  
Growth Factor Receptor ◽  
Platelet Derived Growth Factor ◽  
Severe Fever

scholarly journals Viral Load Dynamics and Clinical Disease Severity in Infants With Respiratory Syncytial Virus Infection

2018 ◽  
Vol 219 (8) ◽  
pp. 1207-1215 ◽  
Author(s):  
Cristina Garcia-Mauriño ◽  
Melissa Moore-Clingenpeel ◽  
Jessica Thomas ◽  
Sara Mertz ◽  
Daniel M Cohen ◽  
...  
Keyword(s):  
Viral Load ◽  
Respiratory Syncytial Virus ◽  
Virus Infection ◽  
Disease Severity ◽  
Respiratory Syncytial Virus Infection ◽  
Clinical Disease ◽  
Syncytial Virus

scholarly journals Plasma Exchange did not Reduce Viral Load in a Recovered Case of Severe Fever with Thrombocytopenia Syndrome

2021 ◽  
Author(s):  
Rie Utsunomiya (Nishimizu) ◽  
Seiji Shiota ◽  
Toshihiro Ishii ◽  
Kaori Sano ◽  
Tadaki Suzuki ◽  
...  
Keyword(s):  
Viral Load ◽  
Plasma Exchange ◽  
Severe Fever
Sign in / Sign up

Export Citation Format

Share Document