scholarly journals New extracellular resistance mechanism for cisplatin

2008 ◽  
Vol 102 (5-6) ◽  
pp. 1044-1049 ◽  
Author(s):  
Corey R. Centerwall ◽  
Deborah J. Kerwood ◽  
Jerry Goodisman ◽  
Bonnie B. Toms ◽  
James C. Dabrowiak
2013 ◽  
Vol 59 (2) ◽  
pp. 81-89
Author(s):  
Tomoaki Soma ◽  
Masafumi Inoue ◽  
Masahiro Inayama ◽  
Hiroya Obayashi ◽  
Naoto Ando

Agrotek ◽  
2018 ◽  
Vol 2 (6) ◽  
Author(s):  
Cipta Meliala ◽  
Felicity Fear ◽  
Denis Tourvieille de Labrouhe

Downy mildew symptoms caused by Plasmopara halstedii encountered in sunflower plantation are varied. This variation may be related to the resistance mechanism presented by plant to the invasion of the fungus. Our objectives were firstly is to evaluate symptom development after fungus race 710 inoculation on some vegetative stage of susceptible hybrid. Second objective is to evaluate the reaction some sunflower genotypes after fungus inoculation. The study was conducted under controlled conditions or under netting cages in the field. The development of downy mildew symptoms were affected by all factors studied. Shoot inoculation may present a good method to produce downy mildew symptom similar to the natural infection. Downy mildew symptom progression may be used to screen a genotype with a horizontal resistance.


2018 ◽  
Author(s):  
Wentao Qin ◽  
Scott Donaldson ◽  
Dan Rogers ◽  
Lahcen Boukhanfra ◽  
Julien Thiefain ◽  
...  

Abstract Many semiconductor products are manufactured with mature technologies involving the uses of aluminum (Al) lines and tungsten (W) vias. High resistances of the vias were sometimes observed only after electrical or thermal stress. A layer of Ti oxide was found on such a via. In the wafer processing, the post W chemical mechanical planarization (WCMP) cleaning left residual W oxide on the W plugs. Ti from the overlaying metal line spontaneously reduced the W oxide, through which Ti oxide formed. Compared with W oxide, the Ti oxide has a larger formation enthalpy, and the valence electrons of Ti are more tightly bound to the O ion cores. As a result, the Ti oxide is more resistive than the W oxide. Consequently, the die functioned well in the first test in the fab, but the via resistance increased significantly after a thermal stress, which led to device failure in the second test. The NH4OH concentration was therefore increased to more effectively remove residual W oxide, which solved the problem. The thermal stress had prevented the latent issue from becoming a more costly field failure.


2013 ◽  
Vol 48 (3) ◽  
pp. 295-302
Author(s):  
Lei Zhenzhen ◽  
Ye Jinglong ◽  
Cheng Haili ◽  
Chen Yun ◽  
Wang Huixing ◽  
...  

This article discusses the augmenting influence of Artesunate (ART) in combination with β-lactams (amoxicillin/clavulanic acid) antibiotic in sepsis mice models infected by a lethal challenge dose of live coagulase positive enterotoxigenic (Sec) MRSA that was isolated from a case of chronic bovine mastitis. The main goal is to find an appropriate treatment to overcome resistance mechanism of MRSA towards β-lactams antibiotic. Fifty healthy adult Swiss mice divided into 5 equal groups were used in the experimental procedure. The infected group that treated with both ART and β-lactams (amoxicillin/clavulanic acid) antibiotic revealed complete inhibition of MRSA count with complete normal macroscopic and histopathological features. We suggest that ART can potentiate the antibacterial action of β-lactams (amoxicillin/Clavulanic) acid against MRSA infection. The combination of ART and antibiotic can overcome MRSA resistance mechanism and so could be considered a novel candidate to overcome mastitis and/or sepsis caused by MRSA.


Crop Science ◽  
1978 ◽  
Vol 18 (2) ◽  
pp. 208-209 ◽  
Author(s):  
T. E. Thompson ◽  
R. E. Shade ◽  
J. D. Axtell

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