Videofluoroscopic assessment of swallowing function in patients with myasthenia gravis

2005 ◽  
Vol 231 (1-2) ◽  
pp. 45-48 ◽  
Author(s):  
Ryuzaburo Higo ◽  
Takaharu Nito ◽  
Niro Tayama
2021 ◽  
Vol 14 ◽  
pp. 175628642110355
Author(s):  
Tobias Warnecke ◽  
Sun Im ◽  
Bendix Labeit ◽  
Olga Zwolinskaya ◽  
Sonja Suntrup-Krüger ◽  
...  

Aims: The flexible endoscopic evaluation of swallowing-tensilon test (FTT) was developed to diagnose myasthenia gravis (MG) in patients with unclear pharyngeal dysphagia. The purpose of this study was to determine sensitivity and specificity of the FTT and compare its diagnostic validity with that of other diagnostic markers. Methods: In this single-centre pragmatic clinical cohort study, a total of 100 patients with unclear pharyngeal dysphagia were eligible to undergo FTT. All patients were subjected to FTT and subsequently followed up clinically. FTT was considered positive if a significant improvement of pharyngeal swallowing function could be objectified endoscopically upon administration of edrophonium chloride. In addition, repetitive nerve stimulation test and serum MG antibody analysis were conducted. Results: All subjects (mean age 62.5 ± 14.1 years, female 33) underwent FTT without any complications. According to the results of the diagnostic procedures and based on long-term clinical follow-up for at least 3 years, 51 patients were finally diagnosed with MG. The sensitivity and specificity for the FTT was 88.2% and 95.9%, respectively. Application of the Cochran’s Q test showed statistically significant heterogeneity among the diagnostic tests, with results indicating FTT performance to be more accurate than the repetitive nerve stimulation results ( p < 0.001) and comparable with serum antibody tests ( p > 0.99). Conclusion: FTT has excellent clinical properties to be used routinely in the assessment of dysphagia with isolated or predominant pharyngeal muscle involvement allowing rapid and accurate diagnosis of MG.


2011 ◽  
Vol 21 (3) ◽  
pp. 89-99
Author(s):  
Michael F. Vaezi

Gastroesophageal reflux disease (GERD) is a commonly diagnosed condition often associated with the typical symptoms of heartburn and regurgitation, although it may present with atypical symptoms such as chest pain, hoarseness, chronic cough, and asthma. In most cases, the patient's reduced quality of life drives clinical care and diagnostic testing. Because of its widespread impact on voice and swallowing function as well as its social implications, it is important that speech-language pathologists (SLPs) understand the nature of GERD and its consequences. The purpose of this article is to summarize the nature of GERD and GERD-related complications such as GERD-related peptic stricture, Barrett's esophagus and adenocarcinoma, and laryngeal manifestations of GERD from a gastroenterologist's perspective. It is critical that SLPs who work with a multidisciplinary team understand terminology, diagnostic tools, and treatment to ensure best practice.


2014 ◽  
Vol 24 (2) ◽  
pp. 67-76 ◽  
Author(s):  
Thomas Watterson ◽  
Lynn Marty Grames

The American Speech-Language-Hearing Association (ASHA) has developed Knowledge and Skills (KAS) recommendations for evaluation of the larynx and swallowing function but the evaluation of velopharyngeal (VP) function has never been addressed. This article will review previous documents that have addressed general endoscopic knowledge and skills and develop a case for a new KAS that specifically addresses visualization and evaluation of the VP mechanism. The new KAS document will delineate and explain the relationship between speech evaluation and visual evaluation of VP physiology. The unique skills required of the speech-language pathologist for this kind of evaluation will be discussed.


2016 ◽  
Vol 22 ◽  
pp. 277-278
Author(s):  
Lima Lawrence ◽  
Aleida Rodriguez ◽  
Tahira Yasmeen ◽  
Erin Drever

2009 ◽  
Vol 56 (S 01) ◽  
Author(s):  
M Bensch ◽  
RP Van Wijk ◽  
C Schimmer ◽  
JH Krannich ◽  
I Aleksic ◽  
...  
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