Transcriptional and epigenetic phenomena in peripheral blood cells of monozygotic twins discordant for alzheimer’s disease, a case report

2017 ◽  
Vol 372 ◽  
pp. 211-216 ◽  
Author(s):  
Claudio D’Addario ◽  
Sussy Bastias Candia ◽  
Beatrice Arosio ◽  
Martina Di Bartolomeo ◽  
Carlo Abbate ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Case Report ◽  
Peripheral Blood ◽  
Blood Cells ◽  
Monozygotic Twins ◽  
Peripheral Blood Cells

Interleukin-18 produced by peripheral blood cells is increased in Alzheimer’s disease and correlates with cognitive impairment

2008 ◽  
Vol 22 (4) ◽  
pp. 487-492 ◽  
Author(s):  
Paola Bossù ◽  
Antonio Ciaramella ◽  
Francesca Salani ◽  
Federica Bizzoni ◽  
Erika Varsi ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Impairment ◽  
Peripheral Blood ◽  
Blood Cells ◽  
Peripheral Blood Cells ◽  
Interleukin 18

Neurotrophin Receptor p75 mRNA Level in Peripheral Blood Cells of Patients with Alzheimer’s Disease

2019 ◽  
Vol 36 (1) ◽  
pp. 101-107
Author(s):  
Yali Xu ◽  
Wei-Wei Li ◽  
Jun Wang ◽  
Chi Zhu ◽  
Ying-Ying Shen ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Peripheral Blood ◽  
Blood Cells ◽  
Mrna Level ◽  
Neurotrophin Receptor ◽  
Peripheral Blood Cells

scholarly journals Cholesterol content in peripheral blood cells of patients with Alzheimer's disease

2020 ◽  
Vol 16 (S2) ◽  
Author(s):  
Angel Martin Montes ◽  
Maria Recuero ◽  
Isabel Sastre ◽  
Juan Maria Sanchez‐Caro ◽  
Ana Frank‐García ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Peripheral Blood ◽  
Blood Cells ◽  
Cholesterol Content ◽  
Peripheral Blood Cells

Drug treatment of Alzheimer's disease patients leads to expression changes in peripheral blood cells

2010 ◽  
Vol 6 (5) ◽  
pp. 386-393 ◽  
Author(s):  
Margaret A. Calciano ◽  
Weiyin Zhou ◽  
Peter J. Snyder ◽  
Richard Einstein
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Drug Treatment ◽  
Peripheral Blood ◽  
Blood Cells ◽  
Peripheral Blood Cells

Monozygotic twins with Alzheimer's disease treated with melatonin: Case report

1998 ◽  
Vol 25 (4) ◽  
pp. 260-263 ◽  
Author(s):  
Luis I. Brusco ◽  
Miguel Márquez ◽  
Daniel P. Cardinali
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Case Report ◽  
Monozygotic Twins

Receptor Mediated Binding of the Fibrinolytic Components, Plasminogen and Urokinase, to Peripheral Blood Cells

1987 ◽  
Vol 58 (03) ◽  
pp. 936-942 ◽  
Author(s):  
Lindsey A Miles ◽  
Edward F Plow
Keyword(s):  
T Cells ◽  
B Cell ◽  
Peripheral Blood ◽  
Binding Sites ◽  
Blood Cells ◽  
High Capacity ◽  
Red Cells ◽  
Peripheral Blood Cells ◽  
Cellular Functions ◽  
Fibrinolytic Proteins

SummaryGlu-plasminogen binds to platelets; the monocytoid line, U937, and the human fetal fibroblast line, GM1380 bind both plasminogen and its activator, urokinase. This study assesses the interaction of these fibrinolytic proteins with circulating human blood cells. Plasminogen bound minimally to red cells but bound saturably and reversibly to monocytes, granulocytes and lymphocytes with apparent Kd values of 0.9-1.4 μM. The interactions were of high capacity with 1.6 to 49 × 105 sites/cell and involved the lysine binding sites of plasminogen. Both T cells and non-rosetting lymphocytes and two B cell lines saturably bound plasminogen. Urokinase bound saturably to gianulocytes, monocytes, non-rosetting lymphocytes and a B cell line, but minimally to T cells, platelets and red cells. Therefore, plasminogen binding sites of high capacity, of similar affinities, and with common recognition specificities are expressed by many peripheral blood cells. Urokinase receptors are also widely distributed, but less so than plasminogen binding sites. The binding ol plasminogen and/ or urokinase to these cells may lead to generation of cell- associated proteolytic activity which contributes to a variety of cellular functions.

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