Anorexia-Cachexia Syndrome: A Systematic Review of the Role of Dietary Polyunsaturated Fatty Acids in the Management of Symptoms, Survival, and Quality of Life

Study objectives were to determine if erythrocyte omega-3 polyunsaturated fatty acids (n-3 PUFAs) increased in women participating in a dietary intervention that reduced inflammation and body weight and examine PUFA associations with markers of inflammation and quality of life (QOL). An experimental pre-post test, single group design was used. Fifteen post-menopausal women with obesity were enrolled in a 12-week pilot intervention focusing on lowering added sugars and increasing fiber and fish rich in n-3 PUFAs. Measurements included fasting blood samples, anthropometric, lifestyle and dietary data collected at baseline, end of intervention (Week 12) and follow-up (Week 24). Primary outcomes were change in erythrocyte PUFAs and associations between erythrocyte PUFAs, QOL (Short Form 12), and inflammatory markers (interleukin-6, tumor necrosis factor-α-receptor 2, and high sensitivity C-reactive protein (CRP)). Fourteen women completed all intervention visits. Mean erythrocyte docosahexaenoic acid and arachidonic acid (AA) increased at Week 12 and Week 24 (p < 0.001 for both), while eicosapentaenoic acid increased at Week 24 (p < 0.01). After adjustment for percent weight change, week 12 QOL related to physical function was significantly associated with erythrocyte linoleic acid (p < 0.05) and trended toward significant association with EPA (p = 0.051); week 24 CRP was directly associated with erythrocyte AA (p < 0.05). Erythrocyte n-3 PUFAs were not associated with inflammation.

Download Full-text

The role of self-efficacy in pain intensity, function, psychological factors, health behaviors, and quality of life in people with rheumatoid arthritis: A systematic review

Physiotherapy Theory and Practice ◽

10.1080/09593985.2018.1482512 ◽

2018 ◽

Vol 36 (1) ◽

pp. 21-37 ◽

Cited By ~ 5

Author(s):

Javier Martinez-Calderon ◽

Mira Meeus ◽

Filip Struyf ◽

Alejandro Luque-Suarez

Keyword(s):

Quality Of Life ◽

Rheumatoid Arthritis ◽

Systematic Review ◽

Health Behaviors ◽

Pain Intensity ◽

Self Efficacy ◽

Psychological Factors ◽

Intensity Function

Download Full-text

The role of dietary polyunsaturated fatty acids and prostaglandins in reducing blood pressure and improving thrombogenic indices

Preventive Medicine ◽

10.1016/0091-7435(83)90172-x ◽

1983 ◽

Vol 12 (1) ◽

pp. 60-69 ◽

Cited By ~ 14

Author(s):

J.M. Iacono ◽

R.M. Dougherty

Keyword(s):

Blood Pressure ◽

Fatty Acids ◽

Polyunsaturated Fatty Acids ◽

Dietary Polyunsaturated Fatty Acids

Download Full-text

Can Medical Herbs Stimulate Regeneration or Neuroprotection and Treat Neuropathic Pain in Chemotherapy-Induced Peripheral Neuropathy?

Evidence-based Complementary and Alternative Medicine ◽

10.1155/2013/423713 ◽

2013 ◽

Vol 2013 ◽

pp. 1-18 ◽

Cited By ~ 32

Author(s):

Sven Schröder ◽

Kathrin Beckmann ◽

Giovanna Franconi ◽

Gesa Meyer-Hamme ◽

Thomas Friedemann ◽

...

Keyword(s):

Quality Of Life ◽

Systematic Review ◽

Clinical Trials ◽

Receptor Agonist ◽

Cannabis Sativa ◽

Neuronal Degeneration ◽

Chinese Language ◽

Acorus Calamus

Chemotherapy-induced neuropathy (CIPN) has a relevant impact on the quality of life of cancer patients. There are no curative conventional treatments, so further options have to be investigated. We conducted a systematic review in English and Chinese language databases to illuminate the role of medical herbs. 26 relevant studies on 5 single herbs, one extract, one receptor-agonist, and 8 combinations of herbs were identified focusing on the single herbsAcorus calamus rhizoma,Cannabis sativa fructus,Chamomilla matricaria,Ginkgo biloba,Salvia officinalis,Sweet bee venom,Fritillaria cirrhosae bulbus,and the herbal combinations Bu Yang Huan Wu, modified Bu Yang Huan Wu plus Liuwei Di Huang, modified Chai Hu Long Gu Mu Li Wan,Geranii herbaplusAconiti lateralis praeparata radix, Niu Che Sen Qi Wan (Goshajinkigan), Gui Zhi Jia Shu Fu Tang (Keishikajutsubuto), Huang Qi Wu Wu Tang (Ogikeishigomotsuto), and Shao Yao Gan Cao Tang(Shakuyakukanzoto). The knowledge of mechanism of action is still limited, the quality of clinical trials needs further improvement, and studies have not yielded enough evidence to establish a standard practice, but a lot of promising substances have been identified. While CIPN has multiple mechanisms of neuronal degeneration, a combination of herbs or substances might deal with multiple targets for the aim of neuroprotection or neuroregeneration in CIPN.

Download Full-text