Controlled drug release applications of the inclusion complex of peracetylated-β-cyclodextrin and water-soluble drugs formed in supercritical carbon dioxide

2010 ◽  
Vol 71 (4) ◽  
pp. 630-633 ◽  
Author(s):  
Min Young Lee ◽  
Hullathy Subban Ganapathy ◽  
Kwon Taek Lim
Author(s):  
Ana Aguiar-Ricardo ◽  
Vasco D. B. Bonifácio ◽  
Teresa Casimiro ◽  
Vanessa G. Correia

The integrated use of supercritical carbon dioxide (scCO 2 ) and micro- and nanotechnologies has enabled new sustainable strategies for the manufacturing of new medications. ‘Green’ scCO 2 -based methodologies are well suited to improve either the synthesis or materials processing leading to the assembly of three-dimensional multifunctional constructs. By using scCO 2 either as C1 feedstock or as solvent, simple, economic, efficient and clean routes can be designed to synthesize materials with unique properties such as polyurea dendrimers and oxazoline-based polymers/oligomers. These new biocompatible, biodegradable and water-soluble polymeric materials can be engineered into multifunctional constructs with antimicrobial activity, targeting moieties, labelling units and/or efficiently loaded with therapeutics. This mini-review highlights the particular features exhibited by these materials resulting directly from the followed supercritical routes.


1997 ◽  
Vol 86 (8) ◽  
pp. 921-928 ◽  
Author(s):  
Lene Frederiksen ◽  
Klaus Anton ◽  
Peter van Hoogevest ◽  
Hans Rudolf Keller ◽  
Hans Leuenberger

2011 ◽  
Vol 72 (1-2) ◽  
pp. 207-212 ◽  
Author(s):  
Tamanna Sultana ◽  
Jae Mok Jung ◽  
Seong-Soo Hong ◽  
Won-Ki Lee ◽  
Yeong-Soon Gal ◽  
...  

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