scholarly journals Diagnostic yield and postoperative mortality associated with surgical lung biopsy for evaluation of interstitial lung diseases: A systematic review and meta-analysis

2015 ◽  
Vol 149 (5) ◽  
pp. 1394-1401.e1 ◽  
Author(s):  
Qian Han ◽  
Qun Luo ◽  
Jia-Xing Xie ◽  
Lu-Lu Wu ◽  
Li-Yue Liao ◽  
...  
Keyword(s):  
Systematic Review ◽  
Lung Biopsy ◽  
Lung Diseases ◽  
Diagnostic Yield ◽  
Meta Analysis ◽  
Postoperative Mortality ◽  
Interstitial Lung Diseases ◽  
Surgical Lung Biopsy

Surgical Lung Biopsy for Interstitial Lung Diseases

CHEST Journal ◽  
2017 ◽  
Vol 151 (5) ◽  
pp. 1131-1140 ◽  
Author(s):  
Rishi Raj ◽  
Kirtee Raparia ◽  
David A. Lynch ◽  
Kevin K. Brown
Keyword(s):  
Lung Biopsy ◽  
Lung Diseases ◽  
Interstitial Lung Diseases ◽  
Surgical Lung Biopsy

scholarly journals Integration of transbronchial cryobiopsy into multidisciplinary board decision: a single center analysis of one hundred consecutive patients with interstitial lung disease

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Katrin E. Hostettler ◽  
Michael Tamm ◽  
Lukas Bubendorf ◽  
Peter Grendelmeier ◽  
Kathleen Jahn ◽  
...  
Keyword(s):  
Clinical Data ◽  
Lung Biopsy ◽  
Lung Diseases ◽  
Diagnostic Yield ◽  
Usual Interstitial Pneumonia ◽  
Diagnostic Value ◽  
Interstitial Lung Diseases ◽  
Histological Findings ◽  
Forceps Biopsy ◽  
Consensus Diagnosis

Abstract Background Transbronchial cryobiopsy in the evaluation of patients with interstitial lung diseases (ILD) is expected to reduce the need for surgical lung biopsy (SLB). Objective To evaluate the diagnostic value of cryobiopsy in combination with bronchoalveolar lavage (BAL), radiologic and clinical data in patients with ILD. Methods Between 08/15 and 01/20 patients with ILD underwent cryobiopsy if they: did not have (i) an usual interstitial pneumonia (UIP)-pattern on CT, (ii) predominant ground-glass opacities suggesting alveolitis, (iii) findings suggestive of sarcoidosis on CT, or if they had (i) a CT showing UIP-pattern, but had findings suggesting alternative diagnosis than idiopathic pulmonary fibrosis (IPF), or (ii) had previous non-diagnostic conventional transbronchial forceps biopsy. Histological findings were integrated into the multidisciplinary team discussion (MDTD) and a diagnostic consensus was sought. Results One hundred patients underwent cryobiopsy. In 88/100 patients, cryobiopsy was representative with diagnostic findings in 45/88 and non-specific histological findings in 43/88 patients. In 25/43 with non-specific findings, a consensus diagnosis was reached after MDTD integrating BAL, radiologic and clinical data; eight of the remaining 18 patients with non-specific findings were referred to SLB. In 12/100 patients cryobiopsy was not representative and three of these patients were also referred to SLB. In 7/11 patients (64%) SLB was diagnostic. Complications of cryobiopsy included pneumothorax (14%) and locally controlled bleeding (24%). Conclusions The diagnostic yield of cryobiopsy was 70%:45% of cryobiopsies were diagnostic based on histology alone and an additional 25% provided non-specific, but valuable findings allowing a consensus diagnosis after MDTD. Our data demonstrate that the diagnostic value of cryobiopsy is high if combined with BAL, radiologic and clinical data.

scholarly journals Poor Concordance between Sequential Transbronchial Lung Cryobiopsy and Surgical Lung Biopsy in the Diagnosis of Diffuse Interstitial Lung Diseases

2019 ◽  
Vol 199 (10) ◽  
pp. 1249-1256 ◽  
Author(s):  
Micaela Romagnoli ◽  
Thomas V. Colby ◽  
Jean-Philippe Berthet ◽  
Anne Sophie Gamez ◽  
Jean-Pierre Mallet ◽  
...  
Keyword(s):  
Lung Biopsy ◽  
Lung Diseases ◽  
Interstitial Lung Diseases ◽  
Surgical Lung Biopsy ◽  
Transbronchial Lung Cryobiopsy
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