Dexmedetomidine alleviates neurobehavioral impairments and myelination deficits following lipopolysaccharide exposure in early postnatal rats

Life Sciences ◽  
2020 ◽  
Vol 263 ◽  
pp. 118556
Author(s):  
Ziyi Wu ◽  
Hang Xue ◽  
Yahan Zhang ◽  
Ping Zhao
Keyword(s):  
Postnatal Rats

Decreased progestin receptors in the cerebral cortex of hypothyroid postnatal rats

1984 ◽  
Vol 20 (4) ◽  
pp. 817-819 ◽  
Author(s):  
Kato Junzo ◽  
Onouchi Tsuneko ◽  
Takamatsu Mitsuko
Keyword(s):  
Cerebral Cortex ◽  
Progestin Receptors ◽  
Postnatal Rats

scholarly journals The hormonal regulation of enzymes in prenatal and postnatal rat liver. Effects of adenosine 3′,5′-(cyclic)-monophosphate

1969 ◽  
Vol 115 (1) ◽  
pp. 19-24 ◽  
Author(s):  
Olga Greengard
Keyword(s):  
Growth Hormone ◽  
Hormonal Regulation ◽  
Time Course ◽  
Tyrosine Aminotransferase ◽  
Cyclic Monophosphate ◽  
Sequential Development ◽  
Foetal Liver ◽  
Old Rats ◽  
Postnatal Rats ◽  
Do So

1. The administration of glucagon, cAMP [adenosine 3′,5′-(cyclic)-monophosphate], BcAMP [6-N-2′-O-dibutyryladenosine 3′,5′-(cyclic)-monophosphate] or adrenaline to foetal rats during the last 2 days of gestation evoked the appearance of tyrosine aminotransferase and enhanced the accumulation of glucose 6-phosphatase in the liver. In foetuses 1–2 days younger only BcAMP was effective. After birth liver glucose 6-phosphatase no longer responds to glucagon or BcAMP. Tyrosine aminotransferase is still inducible by these agents in 2-day-old rats, but not in 50-day-old rats. After adrenalectomy of adults glucagon or BcAMP can enhance the induction of the enzyme by hydrocortisone. The results indicate that the ability to synthesize tyrosine aminotransferase and glucose 6-phosphatase when exposed to cAMP develops sooner than the ability to respond to glucagon with an increase in the concentration of cAMP; the responsiveness of enzymes to different hormones changes with age. A scheme illustrating the sequential development of competence in regulating the level of an enzyme is presented. 2. Actinomycin inhibited the effects of glucagon and BcAMP on liver tyrosine aminotransferase and glucose 6-phosphatase in foetal rats. Growth hormone, insulin and hydrocortisone did not enhance the formation of these enzymes. 3. The time-course of accumulation of glucose 6-phosphatase in the kidney is different from that in the liver. Hormones that increase the accumulation in foetal liver do not do so in the kidney of the same foetus or in the livers of postnatal rats.

Growth and polyploidization of the liver of early postnatal rats treated with blfomycin

1985 ◽  
Vol 9 (11) ◽  
pp. 993-1001 ◽  
Author(s):  
S BARNI ◽  
G BERNOCCHI ◽  
E SCHERINI ◽  
V MARE
Keyword(s):  
Postnatal Rats

Retinal pigment epithelium: pattern of proliferative activity and its regulation by intraocular pressure in postnatal rats

Development ◽  
1983 ◽  
Vol 75 (1) ◽  
pp. 271-291
Author(s):  
O. G. Stroeva ◽  
I. G. Panova
Keyword(s):  
Intraocular Pressure ◽  
Retinal Pigment Epithelium ◽  
Proliferative Activity ◽  
Pigment Epithelium ◽  
Retinal Pigment ◽  
Cell Entry ◽  
Binucleated Cells ◽  
G2 Phase ◽  
Thymidine Autoradiography ◽  
Postnatal Rats

The postnatal proliferative activity of retinal pigment epithelium (RPE) cells and its dependence on intraocular pressure were studied using [3H]thymidine and [14C]thymidine autoradiography in normal and experimentally induced microphthalmic pigmented rats. The regulation of RPE growth by intraocular pressure was shown to involve the control of the number of binucleated cells by means of stimulation of cell entry into the S phase of the cell cycle. Binucleated cells in the rat RPE are formed by acy to kinetic mitoses between days 2 and 9. The significance of the postnatal proliferation and formation of binucleated cells in the RPE is discussed in terms of the specificity of the G2 phase for melanotropic hormone action on RPE differentiation.

A technique for culturing brain nuclei from postnatal rats

1996 ◽  
Vol 26 (2) ◽  
pp. 195-203 ◽  
Author(s):  
Yasuko Nakajima ◽  
Sadahiko Masuko
Keyword(s):  
Brain Nuclei ◽  
Postnatal Rats
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