Prevalence and Prognosis of Nonobstructive Coronary Artery Disease in Patients Undergoing Coronary Angiography or Coronary Computed Tomography Angiography

For diagnosis and treatment planning of patients with stable coronary artery disease, coronary angiography is of particular importance. Invasive coronary angiography is a robust and accurate method for the identification of coronary artery stenoses and occlusions, with the option for immediate intervention. Due to its invasiveness, its small, but not negligible risk for complications, and the fact that angiographic stenosis severity does not closely correspond with ischaemia, coronary angiography is not a first-line test in patients with suspected coronary artery disease. Invasive coronary angiography should be performed when non-invasive testing indicates the presence of relevant ischaemia, when symptoms are compelling and cannot be controlled by medication, or when symptoms are accompanied by reduced left ventricular ejection fraction. In order to determine the presence or absence of ischaemia, invasive coronary angiography can be complemented by fractional flow reserve measurements. Coronary computed tomography angiography is a non-invasive alternative method to visualize the coronary lumen, but requires careful patient selection, data acquisition, and processing. It is not as stable and robust as invasive coronary angiography. However, the use of coronary computed tomography angiography can be considered in patients with a low-to-intermediate risk for coronary artery disease in order to rule out coronary artery stenoses when patient characteristics indicate a high likelihood of fully diagnostic image quality.

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COMPARISON OF RISK PROFILES OF WOMEN WITH INOCA DIAGNOSED BY CORONARY COMPUTED TOMOGRAPHY ANGIOGRAPHY VS INVASIVE CORONARY ANGIOGRAPHY - A SUBSTUDY OF THE WOMEN’S ISCHEMIA TRIAL TO REDUCE EVENTS IN NON-OBSTRUCTIVE CORONARY ARTERY DISEASE (WARRIOR)

Journal of the American College of Cardiology ◽

10.1016/s0735-1097(21)02715-7 ◽

2021 ◽

Vol 77 (18) ◽

pp. 1357

Author(s):

Suvasini Lakshmanan ◽

Janet Wei ◽

Galen Cook-Wiens ◽

Andre Rogatko ◽

Eileen Handberg ◽

...

Keyword(s):

Computed Tomography ◽

Coronary Artery Disease ◽

Coronary Artery ◽

Coronary Angiography ◽

Computed Tomography Angiography ◽

Coronary Computed Tomography Angiography ◽

Invasive Coronary Angiography ◽

Obstructive Coronary Artery Disease ◽

Coronary Computed Tomography ◽

Artery Disease

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Use of Coronary Computed Tomography Angiography to Screen Hospital Employees with Cardiovascular Risk Factors

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18105462 ◽

2021 ◽

Vol 18 (10) ◽

pp. 5462

Author(s):

Po-Yi Li ◽

Ru-Yih Chen ◽

Fu-Zong Wu ◽

Guang-Yuan Mar ◽

Ming-Ting Wu ◽

...

Keyword(s):

Risk Factors ◽

Computed Tomography ◽

Coronary Artery Disease ◽

Coronary Artery ◽

Computed Tomography Angiography ◽

Coronary Computed Tomography Angiography ◽

Significant Risk ◽

Coronary Computed Tomography ◽

Hospital Employees ◽

Artery Disease

The objective of this study was to determine how coronary computed tomography angiography (CCTA) can be employed to detect coronary artery disease in hospital employees, enabling early treatment and minimizing damage. All employees of our hospital were assessed using the Framingham Risk Score. Those with a 10-year risk of myocardial infarction or death of >10% were offered CCTA; the Coronary Artery Disease Reporting and Data System (CAD-RADS) score was the outcome. A total of 3923 hospital employees were included, and the number who had received CCTA was 309. Among these 309, 31 (10.0%) had a CAD-RADS score of 3–5, with 10 of the 31 (32.3%) requiring further cardiac catheterization; 161 (52.1%) had a score of 1–2; and 117 (37.9%) had a score of 0. In the multivariate logistic regression, only age of ≥ 55 years (p < 0.05), hypertension (p < 0.05), and hyperlipidemia (p < 0.05) were discovered to be significant risk factors for a CAD-RADS score of 3–5. Thus, regular and adequate control of chronic diseases is critical for patients, and more studies are required to be confirmed if there are more significant risk factors.

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