GC-MS characterization and evaluation of antimicrobial, anticancer and wound healing efficiency of combined ethanolic extract of Tridax procumbens and Acalypha indica

2021 ◽  
pp. 131678
Author(s):  
A. Sophia ◽  
Md. Faiyazuddin ◽  
Prawez Alam ◽  
Md. Talib Hussain ◽  
Faiyaz Shakeel
Keyword(s):  
Wound Healing ◽  
Ethanolic Extract ◽  
Healing Efficiency ◽  
Tridax Procumbens ◽  
Acalypha Indica

scholarly journals Burn Wound Healing Activity of Ethanolic Extract of Acalypha indica in Oinment Formulated against Rabbits (Ocyctagus caniculus)

2020 ◽  
Vol 8 (3) ◽  
pp. 18-20
Author(s):  
Khairani Fitri ◽  
Tetty Noverita Khairani ◽  
Fajar Apollo Sinaga ◽  
Amenia Gracia Talunohi
Keyword(s):  
Wound Healing ◽  
Ethanolic Extract ◽  
Negative Control ◽  
Burn Wound ◽  
Leaf Extracts ◽  
Laboratory Design ◽  
Burn Wound Healing ◽  
Healing Phase ◽  
Wound Healing Activity ◽  
Acalypha Indica

Objectives: The purpose of this study was to determine burn wound healing activity of Acalypha indica L. in oinment formulated. Design: This study uses an experimental laboratory design. This study used rabbits as test animals induced by burns with hot iron plates on the back. Extract ointment applied to the wound then observed the development of healing. Interventions: The extract was formulated in ointments with concentrations of 3, 5 and 7%. positive control used was ointment containing sesame oil and negative control used is an ointment base. Main outcome measure: The results showed a concentration of 3% had a slow and low effect, at a concentration of 5% it had a moderate healing phase, and a concentration of 7% had a good healing phase. Conclusion: The ointments containing Acalypha indica leaf extracts have good activity in healing burns in rabbits.    

WOUND HEALING ACTIVITY OF AERIAL PARTS OF EUPHORBIA HIRTA LINN. AND ITS POLYHERBAL FORMULATION

INDIAN DRUGS ◽  
2020 ◽  
Vol 57 (07) ◽  
pp. 58-62
Author(s):  
Pushpendra Kumar Jain ◽  
Yogesh Pounikar ◽  
Navneet Khurana
Keyword(s):  
Wound Healing ◽  
Ethanolic Extract ◽  
Albino Rats ◽  
Euphorbia Hirta ◽  
Polyherbal Formulation ◽  
Aerial Parts ◽  
Tridax Procumbens ◽  
Histopathological Studies ◽  
Wound Healing Activity

This study was undertaken to investigate the in vivo wound healing activity of ethanol extracts of the aerial parts of Euphorbia hirta Linn. and its polyherbal formulation with Tridax procumbens and Eclipta alba. The in vivo wound healing activity was assessed in albino rats by using three wound models i.e. excision wound, incision wound and dead space wound models. Level of biochemical markers and histological changes were monitored to evaluate the enhancement of wound healing. The results showed that ethanolic extract ointment possesses a definite prohealing action. This was demonstrated by a significant increase in the rate of wound contraction and by enhanced epithelization. Significant increase in tensile strength, hydroxyproline content and collagen levels were observed, which was further supported by histopathological studies and gain in granuloma breaking strength.

WOUND HEALING ACTIVITY OF THE WHOLE PLANT OF MOMORDICA CHARANTIA LINN. IN RATS

INDIAN DRUGS ◽  
2018 ◽  
Vol 55 (11) ◽  
pp. 64-70
Author(s):  
M.P Singh ◽  
◽  
Y.S. Sarangdevot ◽  
S.S. Sisodia
Keyword(s):  
Wound Healing ◽  
Ethyl Acetate ◽  
Petroleum Ether ◽  
Ethanolic Extract ◽  
Momordica Charantia ◽  
Alcohol Extract ◽  
Whole Plant ◽  
Healing Property ◽  
Aqueous Ethanolic Extract ◽  
Wound Healing Activity

The aim of the present study was to explore the effect of wound healing activity of the whole plant of Momordica charantia Linn. in rats. The effect of aqueous ethanolic extract of Momordica charantia Linn. (Family; Cucurbetaceae) was evaluated on resutured incision, granuloma pouch and excision wound models in rats. The wound healing activity was measured by the rate of wound contraction, skin breaking strength, weight of the granulation tissue, and collagen content. The concentrated ethyl alcohol extract was subject to fractionation by using petroleum ether (40-60o V/V), solvent ether, ethyl acetate, butanol, butanone, ethanol and methanol in succession. All the fractions were screened for wound healing property. The results of pharmacological activity led to the conclusion that the petroleum ether fraction exhibited more significant wound healing promotion property followed by solvent ether and butanone, from all the parameters studied. Ethyl acetate, ethanol and methanol fractions were least effective.

scholarly journals Wound healing activity of Conyza canadensis (L.) Cronquist

2018 ◽  
Vol 1 (T5) ◽  
pp. 35-40
Author(s):  
To Dinh Le ◽  
Nga Thi Hoang ◽  
Nhan Thi Thanh Nguyen ◽  
Thuoc Linh Tran ◽  
Thao Thi Phuong Dang
Keyword(s):  
Wound Healing ◽  
Antibacterial Activity ◽  
Ethyl Acetate ◽  
National Park ◽  
Ethanolic Extract ◽  
Ethyl Acetate Fraction ◽  
Conyza Canadensis ◽  
Keratinocyte Proliferation ◽  
Wound Healing Activity ◽  
Stimulation Of

Conyza canadensis (L.) Cronquist (CCL) has been used by K’Ho minority in Bidoup Nui Ba national park, Lam Dong province, Vietnam as one of wound healing remedies. However, the scientific proof of treatment is still unclear. This study aimed to evaluate this wound healing potential of CCL. CCL power was extracted by ethanol and then partitioned consecutively with petroleum ether, ethyl acetate and water. Wound healing potential was evaluated by antibacterial activity, stimulation of fibroblast and keratinocyte proliferation. Agar-well diffusion was used in the antibacterial tests and the results showed that CCL had antibacterial activity against 02 dermatitis bacteria (Pseudomonas aeruginosa, Staphylococcus aureus) and 02 opportunistic infection bacteria (Escherichia coli, Enterococcus faecalis). Moreover, our results illustrated that CCL stimulated the fibroblast and keratinocyte proliferation compared to the control. Particularly, the fibroblast division increased 1.6 times at 31.25 µg/mL when treated by ethanolic extract, while ethyl acetate fraction showed 1.7 times increase at 10 µg/mL in keratinocyte proliferation compared to the control. Taken together, our study contributed scientific base of CCL in the wound healing.

Biomaterials and controlled release strategy for epithelial wound healing

2019 ◽  
Vol 7 (11) ◽  
pp. 4444-4471 ◽  
Author(s):  
Young Ju Son ◽  
John W. Tse ◽  
Yiran Zhou ◽  
Wei Mao ◽  
Evelyn K. F. Yim ◽  
...  
Keyword(s):  
Wound Healing ◽  
Controlled Release ◽  
Healing Process ◽  
Therapeutic Strategies ◽  
Wound Healing Process ◽  
Healing Efficiency ◽  
Epithelial Wound Healing ◽  
Enhance Wound Healing ◽  
Release Strategy

Skin and cornea tissues provide protective functions. Therapeutics to injuries aim to enhance wound healing efficiency and quality. Although the tissues share similar anatomic structures and wound healing process, therapeutic strategies differ.

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