scholarly journals Variations in the APOE allele or BDNF Val66Met polymorphism are not associated with changes in cognitive function following a tertiary education intervention in older adults: the Tasmanian Healthy Brain Project

2017 ◽  
Vol 55 ◽  
pp. 175-176 ◽  
Author(s):  
Megan E. Thow ◽  
Mathew J. Summers ◽  
Jeffery J. Summers ◽  
Nichole L. Saunders ◽  
James C. Vickers
Keyword(s):  
Older Adults ◽  
Cognitive Function ◽  
Tertiary Education ◽  
Education Intervention ◽  
Val66met Polymorphism ◽  
Apoe Allele ◽  
Bdnf Val66met Polymorphism

O4-06-04: THE BDNF VAL66MET POLYMORPHISM INFLUENCES THE COGNITIVE BENEFITS OF AN EDUCATION INTERVENTION IN OLDER ADULTS

2006 ◽  
Vol 14 (7S_Part_27) ◽  
pp. P1414-P1415
Author(s):  
James C. Vickers ◽  
David D. Ward ◽  
Andrew Robinson ◽  
Mathew J. Summers ◽  
Jeffery J. Summers ◽  
...  
Keyword(s):  
Older Adults ◽  
Education Intervention ◽  
Val66met Polymorphism ◽  
Cognitive Benefits ◽  
Bdnf Val66met Polymorphism

ASSOCIATIONS OF LATER-LIFE EDUCATION, THE BDNF VAL66MET POLYMORPHISM AND COGNITIVE CHANGE IN OLDER ADULTS

2019 ◽  
pp. 1-6
Author(s):  
D.D. Ward ◽  
M.J. Summers ◽  
M.J. Valenzuela ◽  
V.K. Srikanth ◽  
J.J. Summers ◽  
...  
Keyword(s):  
Older Adults ◽  
Language Processing ◽  
Statistical Significance ◽  
Later Life ◽  
Cognitive Change ◽  
Dependent Manner ◽  
Val66met Polymorphism ◽  
Bdnf Val66met Polymorphism ◽  
University Level ◽  
Life Education

In 358 participants of the Tasmanian Healthy Brain Project, we quantified the cognitive consequences of engaging in varying loads of university-level education in later life, and investigated whether or not BDNF Val66Met affected outcomes. Assessment of neuropsychological, health, and psychosocial function was undertaken at baseline, 12-month, and 24-month follow-up. Education load was positively associated with change in language processing performance, but this effect did not reach statistical significance (P = 0.064). The BDNF Val66Met polymorphism significantly moderated the extent to which education load was associated with improved language processing (P = 0.026), with education load having a significant positive relationship with cognitive change in BDNF Met carriers but not in BDNF Val homozygotes. In older adults who carry BDNF Met, engaging in university-level education improves language processing performance in a load-dependent manner.

No association between the BDNF Val66Met polymorphism and mood status in a non-clinical community sample of 7389 older adults

2007 ◽  
Vol 41 (5) ◽  
pp. 404-409 ◽  
Author(s):  
Paul G. Surtees ◽  
Nicholas W.J. Wainwright ◽  
Saffron A.G. Willis-Owen ◽  
Manjinder S. Sandhu ◽  
Robert Luben ◽  
...  
Keyword(s):  
Older Adults ◽  
Community Sample ◽  
Val66met Polymorphism ◽  
Clinical Community ◽  
Bdnf Val66met Polymorphism
Sign in / Sign up

Export Citation Format

Share Document