scholarly journals Characterising group-level brain connectivity: A framework using Bayesian exponential random graph models

NeuroImage ◽  
2021 ◽  
Vol 225 ◽  
pp. 117480
Author(s):  
B.C.L. Lehmann ◽  
R.N. Henson ◽  
L. Geerligs ◽  
Cam-CAN ◽  
S.R. White
Keyword(s):  
Random Graph ◽  
Brain Connectivity ◽  
Group Level ◽  
Exponential Random Graph Models ◽  
Graph Models ◽  
Random Graph Models ◽  
Exponential Random Graph

scholarly journals Characterising group-level brain connectivity: a framework using Bayesian exponential random graph models

2019 ◽  
Author(s):  
Brieuc CL Lehmann ◽  
Richard N Henson ◽  
Linda Geerligs ◽  
Simon R White ◽  
Keyword(s):  
Random Graph ◽  
Brain Connectivity ◽  
Resting State Fmri ◽  
Exponential Random Graph Models ◽  
Graph Models ◽  
Brain Scans ◽  
Connectivity Structure ◽  
Random Graph Models ◽  
Multiple Networks ◽  
Exponential Random Graph

The brain can be modelled as a network with nodes and edges derived from a range of imaging modalities: the nodes correspond to spatially distinct regions and the edges to the interactions between them. Whole-brain connectivity studies typically seek to determine how network properties change with a given categorical phenotype such as age-group, disease condition or mental state. To do so reliably, it is necessary to determine the features of the connectivity structure that are common across a group of brain scans. Given the complex interdependencies inherent in network data, this is not a straightforward task. Some studies construct a group-representative network (GRN), ignoring individual differences, while other studies analyse networks for each individual independently, ignoring information that is shared across individuals. We propose a Bayesian framework based on exponential random graph models (ERGM) extended to multiple networks to characterise the distribution of a entire population of networks. Using resting-state fMRI data from the Cam-CAN project, a study on healthy ageing, we demonstrate how our method can be used to characterise and compare the brain's functional connectivity structure across a group of young individuals and a group of old individuals.

scholarly journals Exponential random graph models for little networks

2021 ◽  
Vol 64 ◽  
pp. 225-238
Author(s):  
George G. Vega Yon ◽  
Andrew Slaughter ◽  
Kayla de la Haye
Keyword(s):  
Random Graph ◽  
Exponential Random Graph Models ◽  
Graph Models ◽  
Random Graph Models ◽  
Exponential Random Graph

scholarly journals The performance of permutations and exponential random graph models when analyzing animal networks

2020 ◽  
Vol 31 (5) ◽  
pp. 1266-1276 ◽  
Author(s):  
Julian C Evans ◽  
David N Fisher ◽  
Matthew J Silk
Keyword(s):  
Social Network ◽  
Random Graph ◽  
False Positive ◽  
False Negative ◽  
Error Rates ◽  
Network Data ◽  
Exponential Random Graph Models ◽  
Graph Models ◽  
Random Graph Models ◽  
Exponential Random Graph

Abstract Social network analysis is a suite of approaches for exploring relational data. Two approaches commonly used to analyze animal social network data are permutation-based tests of significance and exponential random graph models. However, the performance of these approaches when analyzing different types of network data has not been simultaneously evaluated. Here we test both approaches to determine their performance when analyzing a range of biologically realistic simulated animal social networks. We examined the false positive and false negative error rate of an effect of a two-level explanatory variable (e.g., sex) on the number and combined strength of an individual’s network connections. We measured error rates for two types of simulated data collection methods in a range of network structures, and with/without a confounding effect and missing observations. Both methods performed consistently well in networks of dyadic interactions, and worse on networks constructed using observations of individuals in groups. Exponential random graph models had a marginally lower rate of false positives than permutations in most cases. Phenotypic assortativity had a large influence on the false positive rate, and a smaller effect on the false negative rate for both methods in all network types. Aspects of within- and between-group network structure influenced error rates, but not to the same extent. In "grouping event-based" networks, increased sampling effort marginally decreased rates of false negatives, but increased rates of false positives for both analysis methods. These results provide guidelines for biologists analyzing and interpreting their own network data using these methods.

scholarly journals Bayesian exponential random graph models with nodal random effects

2016 ◽  
Vol 46 ◽  
pp. 11-28 ◽  
Author(s):  
S. Thiemichen ◽  
N. Friel ◽  
A. Caimo ◽  
G. Kauermann
Keyword(s):  
Random Effects ◽  
Random Graph ◽  
Exponential Random Graph Models ◽  
Graph Models ◽  
Random Graph Models ◽  
Exponential Random Graph
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