Synthesis of novel 68Ga-labeled amino acid derivatives for positron emission tomography of cancer cells

2010 ◽  
Vol 37 (8) ◽  
pp. 893-902 ◽  
Author(s):  
Dinesh Shetty ◽  
Jae Min Jeong ◽  
Chang Hwan Ju ◽  
Yun-Sang Lee ◽  
Seo Young Jeong ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Amino Acid ◽  
Cancer Cells ◽  
Emission Tomography ◽  
Amino Acid Derivatives ◽  
Positron Emission

Synthesis and evaluation of macrocyclic amino acid derivatives for tumor imaging by gallium-68 positron emission tomography

2010 ◽  
Vol 18 (21) ◽  
pp. 7338-7347 ◽  
Author(s):  
Dinesh Shetty ◽  
Jae Min Jeong ◽  
Chang Hwan Ju ◽  
Young Ju Kim ◽  
Ji-Youn Lee ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Amino Acid ◽  
Tumor Imaging ◽  
Emission Tomography ◽  
Amino Acid Derivatives ◽  
Positron Emission ◽  
Gallium 68

BRAIN TUMOR IMAGING BASED ON C-11 LABELED AMINO ACID UTILIZATION USING POSITRON EMISSION TOMOGRAPHY

1980 ◽  
Vol 15 (5) ◽  
pp. 380
Author(s):  
C Leon Partain ◽  
Karl F. Hubner ◽  
M. Stephen Mahaley ◽  
F. David Rollo ◽  
Ronald R. Price ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Brain Tumor ◽  
Amino Acid ◽  
Tumor Imaging ◽  
Emission Tomography ◽  
Positron Emission ◽  
Amino Acid Utilization

Imaging of amino acid transport in brain tumours: Positron emission tomography with O-(2-[ 18 F]fluoroethyl)- L -tyrosine (FET)

Methods ◽  
2017 ◽  
Vol 130 ◽  
pp. 124-134 ◽  
Author(s):  
Karl-Josef Langen ◽  
Gabriele Stoffels ◽  
Christian Filss ◽  
Alexander Heinzel ◽  
Carina Stegmayr ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Amino Acid ◽  
Amino Acid Transport ◽  
Brain Tumours ◽  
Emission Tomography ◽  
Acid Transport ◽  
Positron Emission

scholarly journals Combined Amino Acid Positron Emission Tomography and Advanced Magnetic Resonance Imaging in Glioma Patients

Cancers ◽  
2019 ◽  
Vol 11 (2) ◽  
pp. 153 ◽  
Author(s):  
Philipp Lohmann ◽  
Jan-Michael Werner ◽  
N. Shah ◽  
Gereon Fink ◽  
Karl-Josef Langen ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Positron Emission Tomography ◽  
Amino Acid ◽  
Magnetic Resonance ◽  
Emission Tomography ◽  
Chemical Exchange Saturation Transfer ◽  
Resonance Imaging ◽  
Methodological Innovation ◽  
Positron Emission ◽  
Amino Acid Pet

Imaging techniques such as positron emission tomography (PET) and magnetic resonance imaging (MRI) provide valuable information about brain tumor patients. Particularly amino acid PET, advanced MRI techniques, and combinations thereof are of great interest for the non-invasive assessment of biological characteristics in patients with primary or secondary brain cancer. A methodological innovation that potentially advances research in patients with brain tumors is the increasing availability of hybrid PET/MRI systems, which enables the simultaneous acquisition of both imaging modalities. Furthermore, the advent of ultra-high field MRI scanners operating at magnetic field strengths of 7 T or more will allow further development of metabolic MR imaging at higher resolution. This review focuses on the combination of amino acid PET with MR spectroscopic imaging, perfusion- and diffusion-weighted imaging, as well as chemical exchange saturation transfer in patients with high-grade gliomas, especially glioblastomas.

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