It is well known that subgrid models such as Smagorinsky's cannot be used for the spatially growing simulation of the transition to turbulence of flat-plate boundary layers, unless large-amplitude perturbations are introduced at the upstream boundary: they are over-dissipative, and the flow simulated remains laminar. This is also the case for the structure-function model (SF) of Métais & Lesieur (1992). In the present paper we present a sequel to this model, the filtered-structure-function (FSF) model. It consists of removing the large-scale fluctuations of the field before computing its second-order structure function. Analytical arguments confirm the superiority of the FSF model over the SF model for large-eddy simulations of weakly unstable transitional flows. The FSF model is therefore used for the simulation of a quasi-incompressible (M∞ = 0.5) boundary layer developing spatially over an adiabatic flat plate, with a low level of upstream forcing. With the minimal resolution 650 × 32 × 20 grid points covering a range of streamwise Reynolds numbers Rex1 ε [3.4 × 105, 1.1 × 106], transition is obtained for 80 hours of time-processing on a CRAY 2 (whereas DNS of the whole transition takes about ten times longer). Statistics of the LES are found to be in acceptable agreement with experiments and empirical laws, in the laminar, transitional and turbulent parts of the domain. The dynamics of low-pressure and high-vorticity distributions is examined during transition, with particular emphasis on the neighbourhood of the critical layer (defined here as the height of the fluid travelling at a speed equal to the phase speed of the incoming Tollmien–Schlichting waves). Evidence is given that a subharmonic-type secondary instability grows, followed by a purely spanwise (i.e. time-independent) mode which yields peak-and-valley splitting and transition to turbulence. In the turbulent region, flow visualizations and local instantaneous profiles are provided. They confirm the presence of low- and high-speed streaks at the wall, weak hairpins stretched by the flow and bursting events. It is found that most of the vorticity is produced in the spanwise direction, at the wall, below the high-speed streaks. Isosurfaces of eddy viscosity confirm that the FSF model does not perturb transition much, and acts mostly in the vicinity of the hairpins.