What’s the “catch” in upper-limb post-stroke spasticity: Expanding the role of botulinum toxin applications

2011 ◽  
Vol 17 ◽  
pp. S3-S10 ◽  
Author(s):  
Raymond L. Rosales ◽  
Petr Kanovsky ◽  
Hubert H. Fernandez
Toxins ◽  
2013 ◽  
Vol 5 (5) ◽  
pp. 983-991
Author(s):  
Woo-Jin Kim ◽  
Witsanu Kumthornthip ◽  
Byung Oh ◽  
Eun Yang ◽  
Nam-Jong Paik

2021 ◽  
Vol 25 (3) ◽  
Author(s):  
Zuzanna Olszewska ◽  
Elżbieta Mirek ◽  
Kinga Opoka-Kubica ◽  
Szymon Pasiut Szymon Pasiut ◽  
Magdalena Filip

Introduction: Stroke is a serious health problem in the modern population. Spasticity is one of the consequences of stroke and affects about 30% of people. Increased muscle tone affects postural control disorders. Due to the specificity of spasticity, therapy in post-stroke patients is a challenge for neurological physiotherapy. Therefore, it requires the development of appropriate management standards . Study aim: The aim of the study was to evaluate the effectiveness of 3 combination therapy cycles based on botulinum toxin injection and physiotherapy for muscle tone, muscle strength and postural stability in post-stroke patients qualified for the spasticity treatment programme of the lower and upper limbs. Material and methods: The pilot study involved 12 patients (6 from the lower limb and 6 from the upper limb programme). The 1-year combination therapy programmes included 3 botulinum toxin injections and 3 weeks of physiotherapy after each injection. Clinical evaluation was conducted before and after the 1-year observation cycle. The results were evaluated using: MAS (Modified Ashworth Scale), MRC (Medical Research Council Scale) and posture stability test on a balance platform (BiodexSD). Results: A decrease was observed in muscle tone of the lower and upper limbs, as well as an increase in muscular strength of the upper limb. However, there were no noted statistical significance of the studied parameters. Conclusions: Physiotherapy in combination with the botulinum toxin is an important element of improvement in post-stroke patients. However, further research is needed to explicitly confirm its effectiveness.


2017 ◽  
Vol 2 (1) ◽  

Shoulder pain is a very common complication after stroke, with a reported prevalence varying from 23% to 64%. There are very few treatment options that have been shown to be more effective than placebo for relief of poststroke shoulder pain. One of the factors most frequently associated with shoulder pain is spasticity, especially when the muscles are stretched. Botulinum toxin A (BT-A) is one of the treatments available for the treatment of focal spasticity and its effectiveness in reducing upper limb spasticity in stroke is well documented. In this review, patients with shoulder pain and spasticity after hemiplegia, a single injection of BT-A was associated with a statistically significantly greater reduction in shoulder pain on a numerical rating scale (NRS) from 6/10 at initial assessment; to 1/10 two months post injection. Nine patients (56%) were pain free at 5 and 9 months postinjection. Median Modified Ashworth Scale (MAS) scores for shoulder spasticity in the affected upper limb improved from 3 at the initial assessment to 2, two months post injection and remained as 1+, five and nine months post injection. There was also a significant improvement in median passive shoulder abduction range of motion on the affected upper limb from 80 degrees at the initial assessment to 95 degrees, two months post injection and further improvement to 110 degrees in 9 patients, 5 months post injection. BT-A seems to be effective in managing post- stroke shoulder pain secondary to spasticity.


2011 ◽  
Vol 43 (11) ◽  
pp. 1032-1037 ◽  
Author(s):  
IJ Baguley ◽  
MT Nott ◽  
L Turner-Stokes ◽  
S De Graaff ◽  
P Katrak ◽  
...  

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