Brain changes in children and adolescents with obsessive–compulsive disorder before and after treatment: A voxel-based morphometric MRI study

2009 ◽  
Vol 172 (2) ◽  
pp. 140-146 ◽  
Author(s):  
Luisa Lázaro ◽  
Nuria Bargalló ◽  
Josefina Castro-Fornieles ◽  
Carles Falcón ◽  
Susana Andrés ◽  
...  
2021 ◽  
Vol 128 (9) ◽  
pp. 1445-1459 ◽  
Author(s):  
Karsten Hollmann ◽  
Katharina Allgaier ◽  
Carolin S. Hohnecker ◽  
Heinrich Lautenbacher ◽  
Verena Bizu ◽  
...  

AbstractCognitive behavioral therapy (CBT) is the first choice of treatment of obsessive–compulsive disorder (OCD) in children and adolescents. However, there is often a lack of access to appropriate treatment close to the home of the patients. An internet-based CBT via videoconferencing could facilitate access to state-of-the-art treatment even in remote areas. The aim of this study was to investigate feasibility and acceptability of this telemedical approach. A total of nine children received 14 sessions of CBT. The first session took place face-to-face, the remaining 13 sessions via videoconference. OCD symptoms were recorded with a smartphone app and therapy materials were made accessible in a data cloud. We assessed diagnostic data before and after treatment and obtained measures to feasibility, treatment satisfaction and acceptability. Outcomes showed high acceptance and satisfaction on the part of patients with online treatment (89%) and that face-to-face therapy was not preferred over an internet-based approach (67%). The majority of patients and their parents classified the quality of treatment as high. They emphasized the usefulness of exposures with response prevention (E/RP) in triggering situations at home. The app itself was rated as easy to operate and useful. In addition to feasibility, a significant decrease in obsessive–compulsive symptoms was also achieved. Internet-based CBT for pediatric OCD is feasible and well received by the patients and their parents. Furthermore, obsessive–compulsive symptomatology decreased in all patients. The results of this study are encouraging and suggest the significance of further research regarding this technology-supported approach, with a specific focus on efficacy.Trial registration number: Clinical trials AZ53-5400.1-004/44.


2020 ◽  
Vol 9 (S1) ◽  
pp. S76-S93
Author(s):  
Ahsan Nazeer ◽  
Finza Latif ◽  
Aisha Mondal ◽  
Muhammad Waqar Azeem ◽  
Donald E. Greydanus

2005 ◽  
Vol 35 (7) ◽  
pp. 1007-1017 ◽  
Author(s):  
ARMELLE VIARD ◽  
MARTINE F. FLAMENT ◽  
ERIC ARTIGES ◽  
STANISLAS DEHAENE ◽  
LIONEL NACCACHE ◽  
...  

2005 ◽  
Vol 46 (6) ◽  
pp. 453-459 ◽  
Author(s):  
Steffen Moritz ◽  
Michael Rufer ◽  
Susanne Fricke ◽  
Anne Karow ◽  
Matthias Morfeld ◽  
...  

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