Site specific diagnostic yield of endoscopic biopsies in Gastrointestinal Graft-versus-Host Disease: A tertiary care Center experience

2019 ◽  
Vol 67 (1) ◽  
pp. 16-19 ◽  
Author(s):  
Fady Daniel ◽  
Lara Hassoun ◽  
Mohammad Husni ◽  
Alaa Sharara ◽  
Assad Soweid ◽  
...  
Keyword(s):  
Graft Versus Host Disease ◽  
Diagnostic Yield ◽  
Care Center ◽  
Tertiary Care ◽  
Tertiary Care Center ◽  
Site Specific ◽  
Host Disease ◽  
Graft Versus Host ◽  
Endoscopic Biopsies

scholarly journals S563 Diagnostic Yield of Upper and Lower Endoscopic Biopsies for Evaluation of Suspected Acute Gastrointestinal Graft-Versus-Host Disease

2021 ◽  
Vol 116 (1) ◽  
pp. S257-S257
Author(s):  
Sailaja Pisipati ◽  
Kevin Song ◽  
Suaka Kagbo-Kue ◽  
Jonathan A. Leighton ◽  
Kevin C. Ruff ◽  
...  
Keyword(s):  
Graft Versus Host Disease ◽  
Diagnostic Yield ◽  
Host Disease ◽  
Graft Versus Host ◽  
Endoscopic Biopsies

scholarly journals Pattern of Dermatological Disease Encountered in a Hematology Ward: A Retrospective Analysis of Dermatology Consultation in a Hematology Ward in a Tertiary Care Center in Saudi Arabia

2019 ◽  
Vol 2019 ◽  
pp. 1-5
Author(s):  
Amal Aboud Alasmari ◽  
Anadel Hassan Hakeem ◽  
Fatemah Saleh Bin Saleh ◽  
Shahad Yousef Alsaigh ◽  
Waleed Al Ajroush ◽  
...  
Keyword(s):  
Skin Biopsy ◽  
Graft Versus Host Disease ◽  
Care Center ◽  
Tertiary Care ◽  
Dermatology Department ◽  
Diverse Range ◽  
Cutaneous Manifestations ◽  
Host Disease ◽  
Graft Versus Host ◽  
Dermatological Disease

Introduction. Skin manifestations are common in hematology ward patients and can result from infection, malignancy, or chemotherapy. The purpose of this study was to identify the most common dermatological problems encountered in the adult hematology ward at King Abdullah Specialist Children Hospital (KASCH). Methods. This was retrospective chart review of 78 dermatology consultations based on electronic health records for all inpatients in hematology wards at KASCH between January 2016 and December 2017. Data were presented as mean ± SD for continuous variables. Results. During the study period, a total of 1391 inpatients were referred to the dermatology department. A total of 403 (29.0%) referrals were from the internal medicine department and 78 (5.6%) were from the hematology department, six of which were rejected by the dermatology department. Almost all requests for referral were managed on the same or the next day with only two requests after 3 days. There were more female (n = 40; 51.3%) than male patients (n = 38; 48.7%) and the average age ± SD was 40.7 ± 19.8 years. Patients were diagnosed with a diverse range of hematological diseases. A total of 27 (35.1%) patients were diagnosed with acute myeloid leukemia. Overall, 98 differential diagnoses were made by dermatologists with only 26 being confirmed by skin biopsy. Eight (30.8%) patients were diagnosed with graft versus host disease confirmed by skin biopsy. The diagnoses were changed in 12 cases after skin biopsy. Several types of dermatitis were diagnosed in hematology ward patients including stasis dermatitis and contact dermatitis. The source of infection was not specified in most cases and the infection was treated empirically. Conclusion. Various dermatological disorders and cutaneous manifestations are observed in hematology inpatients with morbilliform drug eruption and graft versus host disease being the most common.

scholarly journals Frequency and Outcome of Graft versus Host Disease after Stem Cell Transplantation: A Six-Year Experience from a Tertiary Care Center in Pakistan

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Natasha Ali ◽  
Salman Naseem Adil ◽  
Mohammad Usman Shaikh ◽  
Nehal Masood
Keyword(s):  
Stem Cell ◽  
Stem Cell Transplantation ◽  
Cell Transplantation ◽  
Graft Versus Host Disease ◽  
Myeloid Leukemia ◽  
Care Center ◽  
Chronic Gvhd ◽  
Tertiary Care ◽  
Host Disease ◽  
Graft Versus Host

Objective. The objective of this study was to evaluate the frequency and outcome of graft versus host disease after stem cell transplantation for various haematological disorders in Pakistan. Materials and Methods. Pretransplant workup of the patient and donor was performed. Mobilization was done with G-CSF 300 μg twice daily for five day. Standard GvHD prophylaxis was done with methotrexate 15 mg/m2 on day +1 followed by 10 mg/m2 on days +3 and +6 and cyclosporine. Grading was done according to the Glucksberg classification. Results. A total of 153 transplants were done from April 2004 to December 2011. Out of these were allogeneic transplants. There were females and males. The overall frequency of any degree of graft versus host disease was 34%. Acute GvHD was present in patients while had chronic GvHD. Grade II GvHD was present in patients while grade III and IV GvHD was seen in patients each. Acute myeloid leukemia and chronic myeloid leukemia were most commonly associated with GvHD. The mortality in acute and chronic GvHD was 8.8% and 12% respectively. Conclusion. The frequency of graft versus host disease in this study was 34% which is lower compared to international literature. The decreased incidence can be attributed to reduced diversity of histocompatibility antigens in our population.

Chronic cutaneous graft-versus-host disease in children: A report of 14 patients from a tertiary care pediatric dermatology clinic

2018 ◽  
Vol 35 (3) ◽  
pp. 343-353 ◽  
Author(s):  
Arti Nanda ◽  
Maitham A. A. Husain ◽  
Waleed Al-Herz ◽  
Adla Almekaimi ◽  
Humoud Al-Sabah ◽  
...  
Keyword(s):  
Graft Versus Host Disease ◽  
Tertiary Care ◽  
Pediatric Dermatology ◽  
Host Disease ◽  
Graft Versus Host ◽  
Dermatology Clinic
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