Development of an HPLC method for the determination of mexiletine in human plasma and urine by solid-phase extraction

Talanta ◽  
2007 ◽  
Vol 72 (3) ◽  
pp. 1172-1177 ◽  
Author(s):  
Sevgi Tatar Ulu
Keyword(s):  
Solid Phase Extraction ◽  
Human Plasma ◽  
Solid Phase ◽  
Hplc Method ◽  
Phase Extraction ◽  
Human Plasma And Urine

Development of an HPLC method for the determination of nifedipine in human plasma by solid-phase extraction

2006 ◽  
Vol 839 (1-2) ◽  
pp. 85-88 ◽  
Author(s):  
Dragica Zendelovska ◽  
Suzana Simeska ◽  
Olgica Sibinovska ◽  
Elena Kostova ◽  
Kalina Miloševska ◽  
...  
Keyword(s):  
Solid Phase Extraction ◽  
Human Plasma ◽  
Solid Phase ◽  
Hplc Method ◽  
Phase Extraction

Magnetic solid-phase extraction based on a trimethylstearylammonium bromide coated Fe3O4/SiO2 composite for determination of adriamycin hydrochloride in human plasma and urine by HPLC-FLD

2014 ◽  
Vol 6 (17) ◽  
pp. 6736-6744 ◽  
Author(s):  
Nengxuan Ma ◽  
Lin Zhang ◽  
Ruijin Li ◽  
Yehong Zhou ◽  
Zongwei Cai ◽  
...  
Keyword(s):  
Solid Phase Extraction ◽  
Human Plasma ◽  
Solid Phase ◽  
Magnetic Solid Phase Extraction ◽  
Phase Extraction ◽  
Human Plasma And Urine ◽  
Magnetic Solid

A novel TSAB coated Fe3O4/SiO2 MNP was fabricated and used as the adsorbent for magnetic solid-phase extraction of ADR with HPLC-FLD.

scholarly journals Separation and Determination of Paraquat and Diquat in Human Plasma and Urine by Magnetic Dispersive Solid Phase Extraction Coupled with High-Performance Liquid Chromatography

2020 ◽  
Vol 2020 ◽  
pp. 1-12
Author(s):  
Ou Sha ◽  
Bowen Cui ◽  
Xiaobing Chen ◽  
Hua Liu ◽  
Jiawei Yao ◽  
...  
Keyword(s):  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
Solid Phase Extraction ◽  
Human Plasma ◽  
High Performance ◽  
Solid Phase ◽  
Phase Extraction ◽  
Dispersive Solid Phase Extraction ◽  
Human Plasma And Urine

A magnetic dispersive solid phase extraction method coupled with high-performance liquid chromatography was proposed for the simultaneous separation and determination of paraquat (PQ) and diquat (DQ) in human plasma and urine samples. Based on the reduction of PQ and DQ to a blue radical and yellow-green radical by sodium dithionite in an alkaline medium, a fast colorimetric method was also developed for the fast detection of PQ or DQ. In this paper, CoFe2O4@SiO2 magnetic nanoparticles were used as the adsorbent for the magnetic dispersive solid phase extraction of paraquat and diquat, and these two analytes were found to be eluted directly from the adsorbent by NaOH solution. The main factors affecting the extraction efficiency including amount of extractant, extraction time, sample volume, sample solution pH, and elution volume were optimized. Under the optimized experimental conditions, the calibration curve was linear at a concentration range of 28.5–570.2 μg/L, and the correlation coefficient of paraquat and diquat was 0.9986 and 0.9980, respectively. The limits of detection of paraquat and diquat were 4.5 μg/L and 4.3 μg/L. The proposed MSPE-HPLC method was successfully applied to the detection of the paraquat and diquat in human plasma and urine with satisfied recoveries of PQ and DQ in the range of 87.5%–98.7%.

scholarly journals HPLC method for determination of verapamil in human plasma after solid-phase extraction

2008 ◽  
Vol 70 (6) ◽  
pp. 1297-1303 ◽  
Author(s):  
Violeta Ivanova ◽  
Dragica Zendelovska ◽  
Marina Stefova ◽  
Trajče Stafilov
Keyword(s):  
Solid Phase Extraction ◽  
Human Plasma ◽  
Solid Phase ◽  
Hplc Method ◽  
Phase Extraction

Capillary gas chromatographic determination of epomediol in human plasma and urine using a rapid solid-phase extraction

1989 ◽  
Vol 3 (5) ◽  
pp. 199-202
Author(s):  
Maria Angela Girometta ◽  
Loredana Loschi ◽  
Paolo Ventura ◽  
Sergio Canali ◽  
Claudio Giachetti ◽  
...  
Keyword(s):  
Solid Phase Extraction ◽  
Human Plasma ◽  
Solid Phase ◽  
Chromatographic Determination ◽  
Phase Extraction ◽  
Human Plasma And Urine
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