Radioligand binding assay for accurate determination of nuclear retinoid X receptors: A case of triorganotin endocrine disrupting ligands

2016 ◽  
Vol 254 ◽  
pp. 32-36 ◽  
Author(s):  
Lucia Toporova ◽  
Dana Macejova ◽  
Julius Brtko
Keyword(s):  
Binding Assay ◽  
Radioligand Binding ◽  
Accurate Determination ◽  
Radioligand Binding Assay ◽  
Retinoid X Receptors ◽  
Endocrine Disrupting ◽  
X Receptors

scholarly journals A rapid bead-based radioligand binding assay for the determination of target-binding fraction and quality control of radiopharmaceuticals

2019 ◽  
Vol 71 ◽  
pp. 32-38 ◽  
Author(s):  
Sai Kiran Sharma ◽  
Serge K. Lyashchenko ◽  
Hijin A. Park ◽  
Nagavarakishore Pillarsetty ◽  
Yorann Roux ◽  
...  
Keyword(s):  
Quality Control ◽  
Binding Assay ◽  
Radioligand Binding ◽  
Radioligand Binding Assay ◽  
Target Binding

Simple Radioligand Binding Assay for the Determination of Urinary Scopolamine

1984 ◽  
Vol 73 (4) ◽  
pp. 561-563 ◽  
Author(s):  
M. Scheurlen ◽  
H. Bittiger ◽  
Birgit Ammann
Keyword(s):  
Binding Assay ◽  
Radioligand Binding ◽  
Radioligand Binding Assay

Migraine Patients Show an Increased Density of Dopamine D3 and D4 Receptors on Lymphocytes

Cephalalgia ◽  
2000 ◽  
Vol 20 (1) ◽  
pp. 15-19 ◽  
Author(s):  
P Barbanti ◽  
G Fabbrini ◽  
A Ricci ◽  
M Paola Pascali ◽  
E Bronzetti ◽  
...  
Keyword(s):  
Dopaminergic System ◽  
Binding Assay ◽  
Radioligand Binding ◽  
Peripheral Blood Lymphocytes ◽  
Radioligand Binding Assay ◽  
Dopamine D2 ◽  
Genetic Features ◽  
Dopamine D3 ◽  
Receptor Antibodies

Recent studies have revealed peculiar functional and genetic features of dopamine receptors in migraine. As peripheral blood lymphocytes (PBL) may represent a tool for peripheral detection of neuroreceptors, we compared the expression of dopamine D3 (DRD3) and D4 (DRD4) receptors on PBL in migraine patients and in healthy controls using radioligand binding assay techniques in the presence of antidopamine D2-like receptor antibodies. The dopamine D2-like receptor agonist [3H]7-OH-DPAT was used as a radioligand. An increased density of both DRD3 ( P = 0.0006) and DRD4 ( P = 0.002) on PBL was observed in migraineurs compared with controls. This up-regulation might reflect central and/or peripheral dopamine receptor hypersensitivity due to hypofunction of the dopaminergic system. These findings support the view that dopamine D2-like receptors are involved in the determination of the so-called migraine trait, which may help to elucidate several clinical features of the disease.

A radioligand-binding assay for detecting antibodies specific for proinsulin and insulin using 35S-proinsulin

2003 ◽  
Vol 279 (1-2) ◽  
pp. 173-181 ◽  
Author(s):  
Silvina N. Valdez ◽  
Rubén F. Iacono ◽  
Anabel Villalba ◽  
Alejandro Cardoso Landaburu ◽  
Mario R. Ermácora ◽  
...  
Keyword(s):  
Binding Assay ◽  
Radioligand Binding ◽  
Radioligand Binding Assay
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