Safety of Noncontrast Imaging–Guided Deep Brain Stimulation Electrode Placement in Parkinson Disease

2020 ◽  
Vol 134 ◽  
pp. e1008-e1014
Author(s):  
Joacir Graciolli Cordeiro ◽  
Anthony Diaz ◽  
Jenna Kylene Davis ◽  
Daniel Garbin Di Luca ◽  
Ghulam Farooq ◽  
...  
2020 ◽  
Vol 67 (12) ◽  
pp. 3542-3552
Author(s):  
Chen Li ◽  
Xiaoyao Fan ◽  
Jennifer Hong ◽  
David W. Roberts ◽  
Joshua P. Aronson ◽  
...  

2013 ◽  
Vol 118 (1) ◽  
pp. 192-194 ◽  
Author(s):  
Paul S. Larson ◽  
Steven W. Cheung

The authors report on a case of tinnitus suppression following deep brain stimulation (DBS) for Parkinson disease. A perioperative focal vascular injury to area LC, a locus of the caudate at the junction of the head and body of the caudate nucleus, is believed to be the neuroanatomical correlate. A 56-year-old woman underwent surgery for implantation of a DBS lead in the subthalamic nucleus to treat medically refractory motor symptoms. She had comorbid tinnitus localized to both ears. The lead trajectory was adjacent to area LC. Shortly after surgery, she reported tinnitus suppression in both ears. Postoperative MRI showed focal hyperintensity of area LC on T2-weighted images. At 18 months, tinnitus localized to the ipsilateral ear remained completely silenced, and tinnitus localized to the contralateral ear was substantially suppressed due to left area LC injury. To the authors' knowledge, this is the first report of a discrete injury to area LC that resulted in bilateral tinnitus suppression. Clinicians treating patients with DBS may wish to include auditory phantom assessment as part of the neurological evaluation.


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