Clinical Presentation and Surgical Outcomes Based on Age and Tumor Topography in 59 Patients With Spinal Dermoid Cysts

Author(s):  
Sauradeep Sarkar ◽  
Vedantam Rajshekhar
2011 ◽  
Vol 121 (11) ◽  
pp. 2282-2289 ◽  
Author(s):  
Jon-Paul Pepper ◽  
Sarah L. Hecht ◽  
Stephen S. Gebarski ◽  
Erin M. Lin ◽  
Stephen E. Sullivan ◽  
...  

2011 ◽  
Vol 22 (5) ◽  
pp. 505-512 ◽  
Author(s):  
Hayrullah DERICI ◽  
Erdinc KAMER ◽  
Cemal KARA ◽  
Haluk Recai UNALP ◽  
Tugrul TANSUG ◽  
...  

Author(s):  
Dr Kouassi Armel Serge Kouame ◽  
Dr Aboulfeth El Mehdi ◽  
Dr Bouzroud Mohamed ◽  
Pr Najih Mohamed ◽  
Pr Kaoui Hakim ◽  
...  

Cystic lymphangioma is a rare malformative benign tumour of the lymph vessels, its histogenesis is still hypothetical. This tumour is mainly found in child’s neck and axillary, the pancreatic location remains exceptional and represents less than 1% of whole lymphangiomas, and occurs more frequently in women and especially in the left pancreas. Its clinical presentation is polymorphic; however, the diagnosis can’t be specifically evoked by imaging and requires therefore histological confirmation. Surgery remains the only curative treatment. We report in this work the case of an incidentally discovered cystic lymphangioma of the pancreatic tail in a 58-year-old woman. The histological study of the surgical specimen concluded on a benign cystic lymphangioma. On later surgical outcomes, the patient developed a pseudokyst of the remaining pancreas and today she has not had any recurrences. The aim of this article is to share our experience in the management of this case and to review the clinical and therapeutic aspects of this rare pathology.


Author(s):  
Shoko Hara ◽  
Maki Mukawa ◽  
Hiroyuki Akagawa ◽  
Thiparpa Thamamongood ◽  
Motoki Inaji ◽  
...  

OBJECTIVE The authors’ objective was to investigate the influence of the RNF213 p.R4810K variant on the clinical presentation and outcomes of Japanese pediatric patients with moyamoya disease. METHODS A total of 129 Japanese patients with pediatric-onset moyamoya disease (onset age ≤ 15 years) who visited the authors’ department from 2012 to 2020 participated in this study. After RNF213 p.R4810K genotyping of each patient was performed, the relationship between genotype and clinical presentation or outcomes, including onset age, initial presentation, surgical outcomes, and subsequent cerebrovascular events, was evaluated. Patients without the p.R4810K variant were tested for RNF213 variants other than p.R4810K. The authors especially focused on the results of patients who presented with moyamoya disease at younger than 1 year of age (infantile onset). RESULTS Compared with the patients with heterozygous variants, patients without the p.R4810K variant were younger at onset (7.1 ± 3.7 vs 4.4 ± 0.9 years), and all 4 patients with infantile onset lacked the p.R4810K variant. A greater proportion of patients without the p.R4810K variant presented with infarction than patients with the heterozygous variant (24.0% vs 7.6%) and a decreased proportion presented with transient ischemic attack (36.0% vs 71.7%). No significant correlation was observed between p.R4810K genotype and clinical outcomes, including surgical outcomes and subsequent cerebrovascular events; however, a decreased proportion of patients without the p.R4810K variant had good surgical outcomes compared with that of patients with the heterozygous variant (76.5% vs 92.2%). Among the 25 patients without the p.R4810K variant, 8 rare variants other than p.R4810K were identified. Three of 4 patients with infantile onset had RNF213 variants other than p.R4810K, which had a more severe functional effect on this gene than p.R4810K. CONCLUSIONS Absence of the RNF213 p.R4810K variant may be a novel biomarker for identification of a severe form of pediatric moyamoya disease.


2016 ◽  
Vol 82 (4) ◽  
pp. 89-92 ◽  
Author(s):  
Joshua H. Uhr ◽  
Jessica Shah ◽  
Richard R.P. Warner ◽  
Celia M. Divino

Author(s):  
Lior Nissim ◽  
Sarah B. Lieber ◽  
Mohammad E. Naffaa ◽  
Mary Louise Fowler ◽  
Robert H. Shmerling ◽  
...  

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