Increased mitochondrial uncoupling proteins, respiratory uncoupling and decreased efficiency in the chronically infarcted rat heart

2008 ◽  
Vol 44 (4) ◽  
pp. 694-700 ◽  
Author(s):  
Andrew J. Murray ◽  
Mark A. Cole ◽  
Craig A. Lygate ◽  
Carolyn A. Carr ◽  
Daniel J. Stuckey ◽  
...  
Keyword(s):  
Rat Heart ◽  
Uncoupling Proteins ◽  
Mitochondrial Uncoupling ◽  
Mitochondrial Uncoupling Proteins ◽  
Respiratory Uncoupling

The Biology of Mitochondrial Uncoupling Proteins

Diabetes ◽  
2004 ◽  
Vol 53 (Supplement 1) ◽  
pp. S130-S135 ◽  
Author(s):  
S. Rousset ◽  
M.-C. Alves-Guerra ◽  
J. Mozo ◽  
B. Miroux ◽  
A.-M. Cassard-Doulcier ◽  
...  
Keyword(s):  
Uncoupling Proteins ◽  
Mitochondrial Uncoupling ◽  
Mitochondrial Uncoupling Proteins

Mitochondrial Uncoupling Proteins in Mammals and Plants

2001 ◽  
Vol 21 (2) ◽  
pp. 201-212 ◽  
Author(s):  
Jirí Borecký ◽  
Ivan G. Maia ◽  
Paulo Arruda
Keyword(s):  
Uncoupling Protein ◽  
Uncoupling Proteins ◽  
Mitochondrial Uncoupling ◽  
Anion Transporter ◽  
Distinct Cluster ◽  
Mitochondrial Uncoupling Proteins ◽  
Shivering Thermogenesis ◽  
General Balance ◽  
Anion Carrier

Uncoupling proteins (UCPs) belong to a distinct cluster of the mitochondrial anion carrier family. Up to five different uncoupling protein types were found in mitochondria of mammals and plants, and recently in fishes, fungi and protozoa. They exhibit a significantly conserved structure with several motifs specific to either the whole cluster or protein type. Uncoupling proteins, as well as the whole mitochondrial anion carrier gene family, probably emerged in evolution before the separation of animal, fungi, and plant kingdoms and originate from an anion/nucleotide or anion/anion transporter ancestor. Mammalian UCP1, UCP2, UCP3, and plant uncoupling proteins pUCP1 and pUCP2 are similar and seem to form one subgroup, whereas UCP4 and BMCP1 belong to a different group. Molecular, biochemical, and phylogenic data suggest that UCP2 could be considered as an UCP-prototype. UCP1 plays its biological role mainly in the non-shivering thermogenesis while the role of the other types is unknown. However, hypotheses have suggested that they are involved in the general balance of basic energy expenditure, protection from reactive oxygen species, and, in plants, in fruit ripening and seed ontogeny.

scholarly journals Mitochondrial uncoupling proteins in unicellular eukaryotes

2010 ◽  
Vol 1797 (6-7) ◽  
pp. 792-799 ◽  
Author(s):  
Wieslawa Jarmuszkiewicz ◽  
Andrzej Woyda-Ploszczyca ◽  
Nina Antos-Krzeminska ◽  
Francis E. Sluse
Keyword(s):  
Uncoupling Proteins ◽  
Mitochondrial Uncoupling ◽  
Unicellular Eukaryotes ◽  
Mitochondrial Uncoupling Proteins

Perspectives on mitochondrial uncoupling proteins-mediated neuroprotection

2014 ◽  
Vol 47 (1-2) ◽  
pp. 119-131 ◽  
Author(s):  
Susana Cardoso ◽  
Sónia Correia ◽  
Cristina Carvalho ◽  
Emanuel Candeias ◽  
Ana I. Plácido ◽  
...  
Keyword(s):  
Uncoupling Proteins ◽  
Mitochondrial Uncoupling ◽  
Mitochondrial Uncoupling Proteins
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