Role of the prefrontal cortex in human episodic memory: Lessons from PET studies

1997 ◽  
Vol 42 (1) ◽  
pp. 75S-76S ◽  
Author(s):  
S. Kapur ◽  
F.I.M. Craik ◽  
E. Tulving ◽  
S. Houle
Keyword(s):  
Prefrontal Cortex ◽  
Episodic Memory

Memory systems, frontal cortex, and the hippocampal axis

1999 ◽  
Vol 22 (3) ◽  
pp. 464-465 ◽  
Author(s):  
Amanda Parker
Keyword(s):  
Prefrontal Cortex ◽  
Episodic Memory ◽  
Frontal Cortex ◽  
Experimental Evidence ◽  
Memory Systems ◽  
Mediodorsal Thalamus ◽  
And Storage

Three comments are made. The proposal that recollection and familiarity-based recognition take different thalamic routes does not fit recent experimental evidence, suggesting that mediodorsal thalamus acts in an integrative role with respect to prefrontal cortex. Second, the role of frontal cortex in episodic memory has been understated. Third, the role of the hippocampal axis is likely to be the computation and storage of ideothetic information.

scholarly journals Cognitive Control of Episodic Memory in Schizophrenia: Differential Role of Dorsolateral and Ventrolateral Prefrontal Cortex

2015 ◽  
Vol 9 ◽  
Author(s):  
John D. Ragland ◽  
Charan Ranganath ◽  
Joshua Phillips ◽  
Megan A. Boudewyn ◽  
Ann M. Kring ◽  
...  
Keyword(s):  
Prefrontal Cortex ◽  
Cognitive Control ◽  
Episodic Memory ◽  
Ventrolateral Prefrontal Cortex

scholarly journals The Role of Prefrontal Cortex in Verbal Episodic Memory: rTMS Evidence

2003 ◽  
Vol 15 (6) ◽  
pp. 855-861 ◽  
Author(s):  
Marco Sandrini ◽  
Stefano F. Cappa ◽  
Simone Rossi ◽  
Paolo M. Rossini ◽  
Carlo Miniussi
Keyword(s):  
Prefrontal Cortex ◽  
Episodic Memory ◽  
Phase Retrieval ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Unrelated Word ◽  
Study Phase ◽  
Memory Processing ◽  
Dorsolateral Prefrontal ◽  
The Right

Long-term, episodic memory processing is supposed to involve the prefrontal cortex asymmetrically. Here we investigate the role of the dorsolateral prefrontal cortex (DLPFC) in encoding and retrieval of semantically related or unrelated word pairs. Subjects were required to perform a task consisting of two parts: a study phase (encoding), in which word pairs were presented, and a test phase (retrieval), during which stimuli previously presented had to be recognized among other stimuli. Consistently with our previous findings using pictures, repetitive transcranial magnetic stimulation (rTMS) had a significant impact on episodic memory. The performance was significantly disrupted when rTMS was applied to the left or right DLPFC during encoding, and to the right DLPFC in retrieval, but only for unrelated word pairs. These results indicate that the nature of the material to be remembered interacts with the encoding–retrieval DLPFC asymmetry; moreover, the crucial role of DLPFC is evident only for novel stimuli.

scholarly journals The Role of Hippocampal–Ventromedial Prefrontal Cortex Neural Dynamics in Building Mental Representations

2021 ◽  
Vol 33 (1) ◽  
pp. 89-103 ◽  
Author(s):  
Anna M. Monk ◽  
Marshall A. Dalton ◽  
Gareth R. Barnes ◽  
Eleanor A. Maguire
Keyword(s):  
Prefrontal Cortex ◽  
Episodic Memory ◽  
Brain Regions ◽  
Ventromedial Prefrontal Cortex ◽  
High Temporal Resolution ◽  
Cognitive Domains ◽  
Initial Stage ◽  
Hippocampal Activity ◽  
Two Stages

The hippocampus and ventromedial prefrontal cortex (vmPFC) play key roles in numerous cognitive domains including mind-wandering, episodic memory, and imagining the future. Perspectives differ on precisely how they support these diverse functions, but there is general agreement that it involves constructing representations composed of numerous elements. Visual scenes have been deployed extensively in cognitive neuroscience because they are paradigmatic multielement stimuli. However, it remains unclear whether scenes, rather than other types of multifeature stimuli, preferentially engage hippocampus and vmPFC. Here, we leveraged the high temporal resolution of magnetoencephalography to test participants as they gradually built scene imagery from three successive auditorily presented object descriptions and an imagined 3-D space. This was contrasted with constructing mental images of nonscene arrays that were composed of three objects and an imagined 2-D space. The scene and array stimuli were, therefore, highly matched, and this paradigm permitted a closer examination of step-by-step mental construction than has been undertaken previously. We observed modulation of theta power in our two regions of interest—anterior hippocampus during the initial stage and vmPFC during the first two stages, of scene relative to array construction. Moreover, the scene-specific anterior hippocampal activity during the first construction stage was driven by the vmPFC, with mutual entrainment between the two brain regions thereafter. These findings suggest that hippocampal and vmPFC neural activity is especially tuned to scene representations during the earliest stage of their formation, with implications for theories of how these brain areas enable cognitive functions such as episodic memory.

The role of prefrontal cortex during tests of episodic memory

1998 ◽  
Vol 2 (10) ◽  
pp. 399-406 ◽  
Author(s):  
Scott F Nolde ◽  
Marcia K Johnson ◽  
Carol L Raye
Keyword(s):  
Prefrontal Cortex ◽  
Episodic Memory

The Role of Attention in Episodic Memory Impairment During Nicotine Withdrawal

2007 ◽  
Author(s):  
Paul S. Merritt ◽  
Adam Cobb ◽  
Luke Moissinac ◽  
Corpus Christi ◽  
Elliot Hirshman
Keyword(s):  
Episodic Memory ◽  
Memory Impairment ◽  
Nicotine Withdrawal
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