Sex differences in the distribution of the steroid receptor coactivator SRC-1 in the song control nuclei of male and female canaries

2003 ◽  
Vol 959 (2) ◽  
pp. 263-274 ◽  
Author(s):  
Thierry D Charlier ◽  
Jacques Balthazart ◽  
Gregory.F Ball
Keyword(s):  
Sex Differences ◽  
Steroid Receptor ◽  
Male And Female ◽  
Steroid Receptor Coactivator ◽  
Song Control Nuclei ◽  
Song Control ◽  
Female Canaries

Song Control Nuclei in Male and Female Large-Billed Crows (Corvus macrorhynchos)

2009 ◽  
Vol 26 (11) ◽  
pp. 771-777 ◽  
Author(s):  
Rui Wang ◽  
YingYu Sun ◽  
XueBo Zhang ◽  
ShaoJu Zeng ◽  
WenQing Xie ◽  
...  
Keyword(s):  
Male And Female ◽  
Song Control Nuclei ◽  
Corvus Macrorhynchos ◽  
Song Control

Sex differences of steroid receptor coactivator-1 expression after spinal cord injury in mice

2017 ◽  
Vol 39 (11) ◽  
pp. 1022-1027 ◽  
Author(s):  
Jiayu Xiao ◽  
Jiqiang Zhang ◽  
Yangang Zhao ◽  
Wenjie Huang ◽  
Zhikai Guo ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Sex Differences ◽  
Steroid Receptor ◽  
Steroid Receptor Coactivator ◽  
Cord Injury

Sex Differences in Neuropeptide B Staining of Song-Control Nuclei in Zebra Finch Brains

1997 ◽  
Vol 50 (5) ◽  
pp. 284-303 ◽  
Author(s):  
Sarah W. Bottjer ◽  
Howard Roselinsky ◽  
Ngoc B. Tran
Keyword(s):  
Sex Differences ◽  
Zebra Finch ◽  
Song Control Nuclei ◽  
Song Control

Sex Differences in Neuropeptide B Staining of Song-Control Nuclei in Zebra Finch Brains (Part 2 of 2)

1997 ◽  
Vol 50 (5) ◽  
pp. 294-303
Author(s):  
Sarah W. Bottjer ◽  
Howard Roselinsky ◽  
Ngoc B. Tran
Keyword(s):  
Sex Differences ◽  
Zebra Finch ◽  
Song Control Nuclei ◽  
Song Control

scholarly journals Genetic Ablation of the Steroid Receptor Coactivator-Ubiquitin Ligase, E6-AP, Results in Tissue-Selective Steroid Hormone Resistance and Defects in Reproduction

2002 ◽  
Vol 22 (2) ◽  
pp. 525-535 ◽  
Author(s):  
Carolyn L. Smith ◽  
Darryll G. DeVera ◽  
Dolores J. Lamb ◽  
Zafar Nawaz ◽  
Yong-Hui Jiang ◽  
...  
Keyword(s):  
Mammary Gland ◽  
Ubiquitin Ligase ◽  
Steroid Hormone ◽  
Steroid Receptor ◽  
Null Mouse ◽  
Wild Type ◽  
Male And Female ◽  
Genetic Ablation ◽  
Steroid Receptor Coactivator

ABSTRACT The E6-associated protein (E6-AP), although originally identified as a ubiquitin ligase, has recently been shown to function as a coactivator of steroid receptor-dependent gene expression in in vitro assays. In order to determine whether E6-AP acts as a coactivator in vivo, physiological parameters associated with male and female sex steroid action were assessed in the E6-AP null mouse. Gonadal size was reduced in E6-AP null male and female mice in comparison to wild-type controls in conjunction with reduced fertility in both genders. Consistent with this observation, defects in sperm production and function, as well as ovulation were observed. In comparison to wild-type controls, induction of prostate gland growth induced by testosterone and uterine growth by estradiol were significantly reduced. In contrast, estrogen and progesterone-stimulated growth of virgin mammary gland was not compromised by E6-AP ablation despite E6-AP expression in this tissue. This latter finding contrasts with the impaired estrogen and progesterone-induced mammary gland development observed previously for steroid receptor coactivator type 1 (SRC-1) and SRC-3 female knockout mice. Taken together, these results are consistent with a role for E6-AP in mediating a subset of steroid hormone actions in vivo. Nevertheless, differences observed between SRC and E6-AP knockout phenotypes indicate that these two families of steroid receptor coactivators are not functionally equivalent and supports the hypothesis that coactivators contribute to tissue-specific steroid hormone action.

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