Cytotoxic effects of the alkaloid chelidonine from chelidonium majus on pancreatic cancer cells. An old and highly potent anticancer drug

2001 ◽  
Vol 120 (5) ◽  
pp. A617-A618
Author(s):  
F GANSAUGE ◽  
M RAMADANI ◽  
S GANSAUGE
Keyword(s):  
Pancreatic Cancer ◽  
Cancer Cells ◽  
Anticancer Drug ◽  
Chelidonium Majus ◽  
Cytotoxic Effects ◽  
Pancreatic Cancer Cells

scholarly journals Enhancement of cytotoxic effects of gemcitabine by Dclk1 inhibition through suppression of Chk1 phosphorylation in human pancreatic cancer cells

2017 ◽  
Vol 38 (5) ◽  
pp. 3238-3244 ◽  
Author(s):  
Daichi Kawamura ◽  
Yoshihiro Takemoto ◽  
Arata Nishimoto ◽  
Koji Ueno ◽  
Tohru Hosoyama ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Cancer Cells ◽  
Human Pancreatic Cancer ◽  
Cytotoxic Effects ◽  
Pancreatic Cancer Cells

Synthesis and cytotoxic effects on pancreatic cancer cells of resveratrol analogs

2019 ◽  
Vol 28 (7) ◽  
pp. 984-991 ◽  
Author(s):  
Barbara De Filippis ◽  
Laura De Lellis ◽  
Rosalba Florio ◽  
Alessandra Ammazzalorso ◽  
Pasquale Amoia ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Cancer Cells ◽  
Cytotoxic Effects ◽  
Pancreatic Cancer Cells ◽  
Resveratrol Analogs

scholarly journals Cytotoxic effects of gemcitabine-loaded solid lipid nanoparticles in pancreatic cancer cells

2020 ◽  
Vol 55 ◽  
pp. 101374 ◽  
Author(s):  
Kevin O. Affram ◽  
Taylor Smith ◽  
Edward Ofori ◽  
Sunil Krishnan ◽  
Patrick Underwood ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Cancer Cells ◽  
Solid Lipid Nanoparticles ◽  
Lipid Nanoparticles ◽  
Cytotoxic Effects ◽  
Solid Lipid ◽  
Pancreatic Cancer Cells

DETECTION OF PANCREATIC CANCER CELLS (SUIT-2) USING AN FET-BASED BIOSENSOR WITH AN EXTENDED Au GATE

2012 ◽  
Vol 24 (02) ◽  
pp. 131-137
Author(s):  
Byunghyun Cho ◽  
Hee-Ho Lee ◽  
Jang-Kyoo Shin ◽  
Masaharu Murata ◽  
Kenoki Ohuchida ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Cancer Cells ◽  
Anticancer Drug ◽  
Medical Application ◽  
Human Pancreatic Cancer ◽  
Labview Software ◽  
Pancreatic Cancer Cells ◽  
Effect Transistor ◽  
The Relationship

In this paper, we assess the feasibility of detecting human pancreatic cancer cells using a field effect transistor (FET)-based biosensor with an extended Au gate for medical application. Pancreatic cancer is one of the most fatal cancers, and is very difficult to diagnose in its early stages. Gemcitabine is an anticancer drug, and when used in chemotherapy it induces cell death. During apoptosis, the surface potential of the pancreatic cancer cells is changed by gemcitabine. In the present study, this change was detected using an FET-based biosensor. This biosensor was fabricated with an extended Au gate, whose surface is a sensing area for cancer cells. A null-balancing circuit was used in the measurement system, and the LabVIEW software platform allowed the immune-reaction at the Au gate to be detected as an output voltage. The cancer cells were incubated for one day; during this time, the cancer cells adhered to the Au extended gate surface. As gemcitabine was introduced to the cancer cells in vitro, changes in the output of the biosensor were monitored. Pancreatic cancer cells with a resistance to gemcitabine were used to verify that the change in the output of the biosensor was due only to the interaction between the cancer cells and the gemcitabine. We also investigated the relationship between the starting time of the reaction and the concentration of the anticancer drug.

scholarly journals Characterization of proteins secreted by pancreatic cancer cells with anticancer drug treatment in vitro

2012 ◽  
Vol 28 (6) ◽  
pp. 1968-1976 ◽  
Author(s):  
TAKANOBU TAKATA ◽  
YASUHITO ISHIGAKI ◽  
TAKEO SHIMASAKI ◽  
HIDEYUKI TSUCHIDA ◽  
YOSHIHARU MOTOO ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Drug Treatment ◽  
Cancer Cells ◽  
Anticancer Drug ◽  
Pancreatic Cancer Cells
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