scholarly journals Sa1136 – Detection of Barrett's Esophagus Through Exhaled Breath Using a Non-Invasive Screening Tool

2019 ◽  
Vol 156 (6) ◽  
pp. S-280
Author(s):  
Yonne Peters ◽  
Ruud W. Schrauwen ◽  
A.C. Tan ◽  
Sanne Bogers ◽  
Bart de Jong ◽  
...  
Keyword(s):  
Barrett’S Esophagus ◽  
Barrett's Esophagus ◽  
Screening Tool ◽  
Exhaled Breath ◽  
Non Invasive

DETECTION OF BARRETT'S ESOPHAGUS THROUGH EXHALED BREATH USING A NON-INVASIVE SCREENING TOOL

2019 ◽  
Author(s):  
Y Peters ◽  
RWM Schrauwen ◽  
AC Tan ◽  
SK Bogers ◽  
B de Jong ◽  
...  
Keyword(s):  
Barrett’S Esophagus ◽  
Barrett's Esophagus ◽  
Screening Tool ◽  
Exhaled Breath ◽  
Non Invasive

Mo1889 Serum Exosomal MicroRNA Expression Can Be a Novel Non-Invasive Strategy for the Screening of Barrett's Esophagus

2013 ◽  
Vol 144 (5) ◽  
pp. S-684 ◽  
Author(s):  
Ajay Bansal ◽  
Xiaoman Hong ◽  
In-hee Lee ◽  
John House ◽  
Sharad C. Mathur ◽  
...  
Keyword(s):  
Barrett’S Esophagus ◽  
Barrett's Esophagus ◽  
Microrna Expression ◽  
Invasive Strategy ◽  
Non Invasive ◽  
Exosomal Microrna

scholarly journals Gastro-Esophageal Reflux Disease Symptoms and Demographic Factors as a Pre-Screening Tool for Barrett’s Esophagus

PLoS ONE ◽  
2014 ◽  
Vol 9 (4) ◽  
pp. e94163 ◽  
Author(s):  
Xinxue Liu ◽  
Angela Wong ◽  
Sudarshan R. Kadri ◽  
Andrej Corovic ◽  
Maria O’Donovan ◽  
...  
Keyword(s):  
Barrett’S Esophagus ◽  
Reflux Disease ◽  
Barrett's Esophagus ◽  
Screening Tool ◽  
Demographic Factors ◽  
Esophageal Reflux ◽  
Disease Symptoms

ASSOCIATION OF EZRIN AND FASCIN EXPRESSION IN BARRETT'S ESOPHAGUS WITH DIFFERENT GRADE OF NON-INVASIVE NEOPLASIA

2009 ◽  
Vol 41 ◽  
pp. S27
Author(s):  
N. De Bortoli ◽  
M.T. Locci ◽  
S. Maltinti ◽  
M. Pesce ◽  
E. Ciancia ◽  
...  
Keyword(s):  
Barrett’S Esophagus ◽  
Barrett's Esophagus ◽  
Non Invasive

Sa1075 Volatile Organic Compounds in Blood for Non-Invasive Diagnosis of Barrett's Esophagus - A Pilot Study

2015 ◽  
Vol 148 (4) ◽  
pp. S-215-S-216
Author(s):  
Amit Bhatt ◽  
Mansour A. Parsi ◽  
Scott L. Gabbard ◽  
Arthi Kumaravel ◽  
David Grove ◽  
...  
Keyword(s):  
Pilot Study ◽  
Volatile Organic Compounds ◽  
Barrett’S Esophagus ◽  
Organic Compounds ◽  
Barrett's Esophagus ◽  
Non Invasive ◽  
Volatile Organic

scholarly journals Sa1153 – Non-Invasive Screening for Barrett's Esophagus Using an Electronic Nose

2019 ◽  
Vol 156 (6) ◽  
pp. S-287-S-288
Author(s):  
Juan Reyes Genere ◽  
Kavel Visrodia ◽  
Liam Zakko ◽  
Bryan Linn ◽  
Magdalen A. Clemens ◽  
...  
Keyword(s):  
Barrett’S Esophagus ◽  
Electronic Nose ◽  
Barrett's Esophagus ◽  
Non Invasive

scholarly journals Challenges in Determining the Role of Microbiome Evolution in Barrett’s Esophagus and Progression to Esophageal Adenocarcinoma

2021 ◽  
Vol 9 (10) ◽  
pp. 2003
Author(s):  
Caitlin Guccione ◽  
Rena Yadlapati ◽  
Shailja Shah ◽  
Rob Knight ◽  
Kit Curtius
Keyword(s):  
Microbial Communities ◽  
Barrett’S Esophagus ◽  
Esophageal Adenocarcinoma ◽  
Barrett's Esophagus ◽  
Distal Esophagus ◽  
First Year ◽  
Endoscopic Screening ◽  
Non Invasive ◽  
Main Driver ◽  
Alternative Means

Esophageal adenocarcinoma (EAC) claims the lives of half of patients within the first year of diagnosis, and its incidence has rapidly increased since the 1970s despite extensive research into etiological factors. The changes in the microbiome within the distal esophagus in modern populations may help explain the growth in cases that other common EAC risk factors together cannot fully explain. The precursor to EAC is Barrett’s esophagus (BE), a metaplasia adapted to a reflux-mediated microenvironment that can be challenging to diagnose in patients who do not undergo endoscopic screening. Non-invasive procedures to detect microbial communities in saliva, oral swabs and brushings from the distal esophagus allow us to characterize taxonomic differences in bacterial population abundances within patients with BE versus controls, and may provide an alternative means of BE detection. Unique microbial communities have been identified across healthy esophagus, BE, and various stages of progression to EAC, but studies determining dynamic changes in these communities, including migration from proximal stomach and oral cavity niches, and their potential causal role in cancer formation are lacking. Helicobacter pylori is negatively associated with EAC, and the absence of this species has been implicated in the evolution of chromosomal instability, a main driver of EAC, but joint analyses of microbiome and host genomes are needed. Acknowledging technical challenges, future studies on the prediction of microbial dynamics and evolution within BE and the progression to EAC will require larger esophageal microbiome datasets, improved bioinformatics pipelines, and specialized mathematical models for analysis.

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