scholarly journals 497 – Hcv Cure by Ifn-Free Direct Acting Antivirals (DAAS) are Associated with Increased Survival in Patients with Hcvrelated Hcc: A Real-World, Propensity Score-Matched Cohort Study from the U.S. and Japan

2019 ◽  
Vol 156 (6) ◽  
pp. S-1200-S-1201
Author(s):  
Hansen Dang ◽  
Yee Hui Yeo ◽  
An K. Le ◽  
Brian T. Nguyen ◽  
Nathan Ramrakhiani ◽  
...  
Keyword(s):  
Cohort Study ◽  
Propensity Score ◽  
Real World ◽  
Matched Cohort ◽  
Direct Acting Antivirals ◽  
Matched Cohort Study ◽  
Direct Acting ◽  
The U.S

scholarly journals Mortality in older adults following a fragility fracture: real-world retrospective matched-cohort study in Ontario

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Jacques P. Brown ◽  
Jonathan D. Adachi ◽  
Emil Schemitsch ◽  
Jean-Eric Tarride ◽  
Vivien Brown ◽  
...  
Keyword(s):  
Cohort Study ◽  
Hip Fracture ◽  
Fragility Fracture ◽  
Mortality Risk ◽  
Real World ◽  
First Year ◽  
Matched Cohort ◽  
Matched Cohort Study ◽  
Fracture Cohort ◽  
One Year

Abstract Background Recent studies are lacking reports on mortality after non-hip fractures in adults aged > 65. Methods This retrospective, matched-cohort study used de-identified health services data from the publicly funded healthcare system in Ontario, Canada, contained in the ICES Data Repository. Patients aged 66 years and older with an index fragility fracture occurring at any osteoporotic site between 2011 and 2015 were identified from acute hospital admissions, emergency and ambulatory care using International Classification of Diseases (ICD)-10 codes and data were analyzed until 2017. Thus, follow-up ranged from 2 years to 6 years. Patients were excluded if they presented with an index fracture occurring at a non-osteoporotic fracture site, their index fracture was associated with a trauma code, or they experienced a previous fracture within 5 years prior to their index fracture. This fracture cohort was matched 1:1 to controls within a non-fracture cohort by date, sex, age, geography and comorbidities. All-cause mortality risk was assessed. Results The survival probability for up to 6 years post-fracture was significantly reduced for the fracture cohort vs matched non-fracture controls (p < 0.0001; n = 101,773 per cohort), with the sharpest decline occurring within the first-year post-fracture. Crude relative risk of mortality (95% confidence interval) within 1-year post-fracture was 2.47 (2.38–2.56) in women and 3.22 (3.06–3.40) in men. In the fracture vs non-fracture cohort, the absolute mortality risk within one year after a fragility fracture occurring at any site was 12.5% vs 5.1% in women and 19.5% vs 6.0% in men. The absolute mortality risk within one year after a fragility fracture occurring at a non-hip vs hip site was 9.4% vs 21.5% in women and 14.4% vs 32.3% in men. Conclusions In this real-world cohort aged > 65 years, a fragility fracture occurring at any site was associated with reduced survival for up to 6 years post-fracture. The greatest reduction in survival occurred within the first-year post-fracture, where mortality risk more than doubled and deaths were observed in 1 in 11 women and 1 in 7 men following a non-hip fracture and in 1 in 5 women and 1 in 3 men following a hip fracture.

Effectiveness of spironolactone dispensation in reducing weekly alcohol use: a retrospective high-dimensional propensity score-matched cohort study

2021 ◽  
Author(s):  
Vanessa A. Palzes ◽  
Mehdi Farokhnia ◽  
Andrea H. Kline-Simon ◽  
Joseph Elson ◽  
Stacy Sterling ◽  
...  
Keyword(s):  
Cohort Study ◽  
Alcohol Use ◽  
Propensity Score ◽  
High Dimensional ◽  
Matched Cohort ◽  
Matched Cohort Study

ID: 3525809 COMPARATIVE OUTCOMES OF ENDOSCOPIC ERADICATION THERAPY FOR DYSPLASTIC BE USING RADIOREQUENCY ABLATION AND CRYOBALLON ABLATION: A MULTICENTER PROPENSITY SCORE MATCHED COHORT STUDY

2021 ◽  
Vol 93 (6) ◽  
pp. AB291-AB292
Author(s):  
Siddharth Agarwal ◽  
Mohammad Alshelleh ◽  
Jamie Scott ◽  
Lovekirat Dhaliwal ◽  
Don C. Codipilly ◽  
...  
Keyword(s):  
Cohort Study ◽  
Propensity Score ◽  
Eradication Therapy ◽  
Matched Cohort ◽  
Matched Cohort Study
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