scholarly journals Purification and characterization of TATA-binding protein promoter binding factor. A regulatory transcription factor of the tbp gene

1994 ◽  
Vol 269 (28) ◽  
pp. 18541-18548
Author(s):  
F. Liu ◽  
E. Bateman
1994 ◽  
Vol 304 (3) ◽  
pp. 981-985 ◽  
Author(s):  
D Civitareale ◽  
A Saiardi ◽  
P Falasca

Thyroid transcription factor 2 binds to the promoters of both thyroglobulin and thyroperoxidase genes, two markers of thyroid tissue differentiation, and its binding modulates the activity of both promoters. In this paper we describe the purification of thyroid transcription factor 2 essentially to homogeneity and demonstrate that it is a thyroid-specific DNA-binding protein. Furthermore, we provide a biochemical characterization suggesting that thyroid transcription factor 2 binds to DNA as a dimer and that it is a zinc-finger DNA-binding protein regulated in vitro by the redox state.


2007 ◽  
Vol 55 (1) ◽  
pp. 84-92 ◽  
Author(s):  
Xiaoxiao Li ◽  
Jianping Lan ◽  
Yuanyuan Zhu ◽  
Jian Yu ◽  
Zhen Dou ◽  
...  

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