scholarly journals A Comparison of Estimates of Michaelis-Menten Kinetic Constants from Various Linear Transformations

1965 ◽  
Vol 240 (2) ◽  
pp. 863-869 ◽  
Author(s):  
John E. Dowd ◽  
Douglas S. Riggs
Keyword(s):  
Kinetic Constants ◽  
Linear Transformations ◽  
Menten Kinetic

Computer Simulation of Amperometric Biosensor Response to Mixtures of Compounds

2002 ◽  
Vol 7 (2) ◽  
pp. 3-14 ◽  
Author(s):  
R. Baronas ◽  
J. Christensen ◽  
F. Ivanauskas ◽  
J. Kulys
Keyword(s):  
Computer Simulation ◽  
Enzymatic Reaction ◽  
Diffusion Equations ◽  
Response Data ◽  
Finite Difference Technique ◽  
Stationary Diffusion ◽  
Biosensor Array ◽  
Menten Kinetic ◽  
Biosensor Response

A mathematical model of amperometric biosensors has been developed. The model bases on non-stationary diffusion equations containing a non-linear term related to Michaelis-Menten kinetic of the enzymatic reaction. The model describes the biosensor response to mixtures of multiple compounds in two regimes of analysis: batch and flow injection. Using computer simulation, large amount of biosensor response data were synthesised for calibration of a biosensor array to be used for characterization of wastewater. The computer simulation was carried out using the finite difference technique.

KINETIC CONSTANTS DETERMINATION OF PETROLEUM REFINERY EFFLUENT TREATMENT IN A UASB REACTOR USING RSM

2017 ◽  
Vol 16 (1) ◽  
pp. 121-130 ◽  
Author(s):  
Seyyed Mohammad Mousavi ◽  
Seyed Omid Rastegar ◽  
Seyed Abbas Shojaosadati ◽  
Soheila Sheibani
Keyword(s):  
Petroleum Refinery ◽  
Kinetic Constants ◽  
Effluent Treatment ◽  
Uasb Reactor ◽  
Refinery Effluent ◽  
Petroleum Refinery Effluent

Supersaturation of solutions in crystallisers with the well stirred suspension

1980 ◽  
Vol 45 (7) ◽  
pp. 1920-1927 ◽  
Author(s):  
Jaroslav Nývlt
Keyword(s):  
High Accuracy ◽  
Nucleation And Growth ◽  
Kinetic Constants ◽  
Derived Relations ◽  
Metastable Region ◽  
The Given

Relations were derived comparing the steady supersaturation in the continuous MSMPR and/or bath crystallisers with the stirred suspension having the maximum supersaturation corresponding to the boundary of metastable region at the given conditions. The derived relations include only the quantities used for the system constant BN from the corresponding crystallisation experiments. By use of supersaturation in the crystalliser obtained by the described method it is possible to evaluate the kinetic constants of nucleation and growth. However, it is not possible to expect a high accuracy of the data so obtained.

Kinetics and mechanism of the reaction of iron(III) with 6-methyl-2,4-heptanedione and 3,5-heptanedione

1990 ◽  
Vol 55 (8) ◽  
pp. 1984-1990 ◽  
Author(s):  
José M. Hernando ◽  
Olimpio Montero ◽  
Carlos Blanco
Keyword(s):  
Aqueous Solution ◽  
Metal Ion ◽  
Activation Parameters ◽  
Enol Form ◽  
Kinetics And Mechanism ◽  
Kinetic Constants ◽  
Steric Factors ◽  
Kinetics Of ◽  
Mechanism Of The Reaction

The kinetics of the reactions of iron(III) with 6-methyl-2,4-heptanedione and 3,5-heptanedione to form the corresponding monocomplexes have been studied spectrophotometrically in the range 5 °C to 16 °C at I 25 mol l-1 in aqueous solution. In the proposed mechanism for the two complexes, the enol form reacts with the metal ion by parallel acid-independent and inverse-acid paths. The kinetic constants for both pathways have been calculated at five temperatures. Activation parameters have also been calculated. The results are consistent with an associative activation for Fe(H2O)63+ and dissociative activation for Fe(H2O)5(OH)2+. The differences in the results for the complexes of heptanediones studied are interpreted in terms of steric factors.

Nonuniform Spatial Deformation of Light Fields by Locally Linear Transformations

2017 ◽  
Vol 36 (4) ◽  
pp. 1
Author(s):  
Clemens Birklbauer ◽  
David C. Schedl ◽  
Oliver Bimber
Keyword(s):  
Light Fields ◽  
Linear Transformations ◽  
Spatial Deformation ◽  
Locally Linear

scholarly journals Interconversion of Plasma Free Thyroxine Values from Assay Platforms with Different Reference Intervals Using Linear Transformation Methods

Biology ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 45
Author(s):  
Fanwen Meng ◽  
Jacqueline Jonklaas ◽  
Melvin Khee-Shing Leow
Keyword(s):  
Linear Transformation ◽  
Piecewise Linear ◽  
Equilibrium Dialysis ◽  
Accurate Method ◽  
Reference Intervals ◽  
Thyroid Stimulating Hormone ◽  
Free Thyroxine ◽  
Thyroid Function Tests ◽  
Linear Transformations ◽  
Transformation Methods

Clinicians often encounter thyroid function tests (TFT) comprising serum/plasma free thyroxine (FT4) and thyroid stimulating hormone (TSH) measured using different assay platforms during the course of follow-up evaluations which complicates reliable comparison and interpretation of TFT changes. Although interconversion between concentration units is straightforward, the validity of interconversion of FT4/TSH values from one assay platform to another with different reference intervals remains questionable. This study aims to establish an accurate and reliable methodology of interconverting FT4 by any laboratory to an equivalent FT4 value scaled to a reference range of interest via linear transformation methods. As a proof-of-concept, FT4 was simultaneously assayed by direct analog immunoassay, tandem mass spectrometry and equilibrium dialysis. Both linear and piecewise linear transformations proved relatively accurate for FT4 inter-scale conversion. Linear transformation performs better when FT4 are converted from a more accurate to a less accurate assay platform. The converse is true, whereby piecewise linear transformation is superior to linear transformation when converting values from a less accurate method to a more robust assay platform. Such transformations can potentially apply to other biochemical analytes scale conversions, including TSH. This aids interpretation of TFT trends while monitoring the treatment of patients with thyroid disorders.

Sign in / Sign up

Export Citation Format

Share Document