scholarly journals Cloning, sequence analysis, and permanent expression of a human α2-adrenergic receptor in Chinese hamster ovary cells

1989 ◽  
Vol 264 (20) ◽  
pp. 11754-11761
Author(s):  
C M Fraser ◽  
S Arakawa ◽  
W R McCombie ◽  
J C Venter
Keyword(s):  
Sequence Analysis ◽  
Chinese Hamster Ovary ◽  
Adrenergic Receptor ◽  
Chinese Hamster Ovary Cells ◽  
Chinese Hamster ◽  
Ovary Cells

DNA sequence analysis of 1-nitrosopyrene-induced mutations in the hprt gene of Chinese hamster ovary cells

1992 ◽  
Vol 13 (5) ◽  
pp. 819-825 ◽  
Author(s):  
Ronald K. Newton ◽  
Robert A. Mittelstaedt ◽  
Mugimane.G. Manjanatha ◽  
Robert.H. Heflich
Keyword(s):  
Sequence Analysis ◽  
Dna Sequence ◽  
Chinese Hamster Ovary ◽  
Chinese Hamster Ovary Cells ◽  
Chinese Hamster ◽  
Dna Sequence Analysis ◽  
Induced Mutations ◽  
Hprt Gene ◽  
Ovary Cells

scholarly journals Expression of three human beta-adrenergic-receptor subtypes in transfected chinese hamster ovary cells

1991 ◽  
Vol 196 (2) ◽  
pp. 357-361 ◽  
Author(s):  
Keri M. TATE ◽  
Marie-M. BRIEND-SUTREN ◽  
Laurent J. EMORINE ◽  
Colette DELAVIER-KLUTCHKO ◽  
Stefano MARULLO ◽  
...  
Keyword(s):  
Chinese Hamster Ovary ◽  
Adrenergic Receptor ◽  
Chinese Hamster Ovary Cells ◽  
Chinese Hamster ◽  
Receptor Subtypes ◽  
Beta Adrenergic Receptor ◽  
Beta Adrenergic ◽  
Ovary Cells

Malignancy-related characteristics of wild type and drug-resistant chinese hamster ovary cells

Pathology ◽  
1993 ◽  
Vol 25 (3) ◽  
pp. 268-276 ◽  
Author(s):  
Wanda B. Mackinnon ◽  
Marlen Dyne ◽  
Rebecca Hancock ◽  
Carolyn E. Mountford ◽  
Adrienne J. Grant ◽  
...  
Keyword(s):  
Chinese Hamster Ovary ◽  
Chinese Hamster Ovary Cells ◽  
Chinese Hamster ◽  
Drug Resistant ◽  
Wild Type ◽  
Ovary Cells

Review of the current methods of Chinese Hamster Ovary (CHO) cells cultivation for production of therapeutic protein

2020 ◽  
Vol 17 ◽  
Author(s):  
Shazid Md. Sharker ◽  
Md. Atiqur Rahman
Keyword(s):  
Chinese Hamster Ovary ◽  
Cho Cells ◽  
Mass Production ◽  
Chinese Hamster Ovary Cells ◽  
Chinese Hamster ◽  
Therapeutic Protein ◽  
Specific Productivity ◽  
Ovary Cells ◽  
Further Development ◽  
Interesting Area

Most of clinical approved protein-based drugs or under in clinical trial have a profound impact in the treatment of critical diseases. The mammalian eukaryotic cells culture approaches, particularly the CHO (Chinese Hamster Ovary) cells are mainly used in the biopharmaceutical industry for the mass-production of therapeutic protein. Recent advances in CHO cell bioprocessing to yield recombinant proteins and monoclonal antibodies have enabled the expression of quality protein. The developments of cell lines are possible to upgrade specific productivity. As a result, it holds an interesting area for academic as well as industrial researchers around the world. This review will concentrate on the recent progress of the mammalian CHO cells culture technology and the future scope of further development for the mass-production of protein therapeutics.

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