scholarly journals Effect of Adrenalectomy and Hypophysectomy on the Circadian Rhythm of β-Hydroxy-β-methylglutaryl Coenzyme A Reductase Activity in Rat Liver

1973 ◽  
Vol 248 (8) ◽  
pp. 2912-2917 ◽  
Author(s):  
Peter A. Edwards
Keyword(s):  
Circadian Rhythm ◽  
Rat Liver ◽  
Coenzyme A ◽  
Reductase Activity ◽  
Coenzyme A Reductase

Regulation of the diurnal rhythm of rat liver β-hydroxy-β-methylglutaryl coenzyme A reductase activity by insulin, glucagon, cyclic AMP and hydrocortisone

1974 ◽  
Vol 160 (2) ◽  
pp. 387-393 ◽  
Author(s):  
Carl M. Nepokroeff ◽  
M.R. Lakshmanan ◽  
Gene C. Ness ◽  
Richard E. Dugan ◽  
John W. Porter
Keyword(s):  
Cyclic Amp ◽  
Rat Liver ◽  
Diurnal Rhythm ◽  
Coenzyme A ◽  
Reductase Activity ◽  
Coenzyme A Reductase

scholarly journals A new method for assaying rat liver microsomal 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity and its application in a study of the effect of dietary cholesterol on this effect of dietary cholesterol on this enzyme

1977 ◽  
Vol 164 (3) ◽  
pp. 501-508 ◽  
Author(s):  
Y A Baqir ◽  
R Booth
Keyword(s):  
Rat Liver ◽  
Cholesterol Ester ◽  
Time Course ◽  
Coenzyme A ◽  
Reductase Activity ◽  
Dietary Cholesterol ◽  
New Method ◽  
Coa Reductase ◽  
Microsomal Cholesterol ◽  
Coenzyme A Reductase

A new method suitable for measuring rat liver 3-hydroxy-3-methylglutaryl-CoA reductase activity is described and its advantages over methods previously available are discussed. An accurate time course was measured for the inhibition of liver microsomal 3-hydroxy-3-methylglutaryl-CoA reductase activity by dietary cholesterol; this enzyme was affected 1 1/4 h after the rats began to consume a cholesterol-rich diet. In this experiment there was no correlation between concentrations of microsomal cholesterol ester and the activity of 3-hydroxy-3-methylglutary-CoA reductase.

scholarly journals Lipoprotein regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in rat liver cell cultures.

1977 ◽  
Vol 252 (8) ◽  
pp. 2726-2733 ◽  
Author(s):  
J L Breslow ◽  
D A Lothrop ◽  
A W Clowes ◽  
S E Lux
Keyword(s):  
Rat Liver ◽  
Cell Cultures ◽  
Liver Cell ◽  
Coenzyme A ◽  
Reductase Activity ◽  
Coenzyme A Reductase

Regulation of rat liver β-hydroxy-β-methylglutaryl coenzyme A reductase activity and cholesterol levels of serum and liver in various dietary and hormonal states

1975 ◽  
Vol 168 (1) ◽  
pp. 89-95 ◽  
Author(s):  
M.R. Lakshmanan ◽  
Richard E. Dugan ◽  
Carl M. Nepokroeff ◽  
Gene C. Ness ◽  
John W. Porter
Keyword(s):  
Rat Liver ◽  
Coenzyme A ◽  
Reductase Activity ◽  
Cholesterol Levels ◽  
Coenzyme A Reductase

Effects of cholesterol uptake from high-density lipoprotein on bile secretion and 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity in perfused rat liver

Metabolism ◽  
1993 ◽  
Vol 42 (5) ◽  
pp. 609-614 ◽  
Author(s):  
Elena Bravo ◽  
Roberto Rivabene ◽  
Flavia Castellano ◽  
Chong Chao Yan ◽  
Alfredo Cantafora ◽  
...  
Keyword(s):  
High Density Lipoprotein ◽  
Rat Liver ◽  
Coenzyme A ◽  
Reductase Activity ◽  
Density Lipoprotein ◽  
Bile Secretion ◽  
High Density ◽  
Perfused Rat Liver ◽  
Cholesterol Uptake ◽  
Coenzyme A Reductase

scholarly journals Specificity of the effect of dietary cholesterol on rat liver microsomal 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity (Short Communication)

1975 ◽  
Vol 148 (2) ◽  
pp. 337-339
Author(s):  
Keith W. Gregory ◽  
Roger Booth
Keyword(s):  
Rat Liver ◽  
Short Communication ◽  
Coenzyme A ◽  
Regulatory Mechanism ◽  
Reductase Activity ◽  
Dietary Cholesterol ◽  
Microsomal Enzymes ◽  
Coa Reductase ◽  
Liver Microsomal Enzymes ◽  
Coenzyme A Reductase

Dietary cholesterol lowers the activity of rat liver microsomal 3-hydroxy-3-methylglutaryl-CoA reductase without affecting various other liver microsomal enzymes. This is consistent with a specific regulatory mechanism and distinguishes the action of cholesterol on 3-hydroxy-3-methylglutaryl-CoA reductase from that of at least one other stimulus known to affect this enzyme.

Sign in / Sign up

Export Citation Format

Share Document