Hepatic triglyceride lipase promotes low density lipoprotein receptor-mediated catabolism of very low density lipoproteins in vitro

Jheem D. Medh; Susan L. Bowen; Glenna L. Fry; Stacie Ruben; John Hill; Howard Wong; David A. Chappell

doi:10.1016/s0022-2275(20)33488-x

Hepatic triglyceride lipase promotes low density lipoprotein receptor-mediated catabolism of very low density lipoproteins in vitro

The Journal of Lipid Research ◽

10.1016/s0022-2275(20)33488-x ◽

1999 ◽

Vol 40 (7) ◽

pp. 1263-1275

Author(s):

Jheem D. Medh ◽

Susan L. Bowen ◽

Glenna L. Fry ◽

Stacie Ruben ◽

John Hill ◽

...

Keyword(s):

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density Lipoproteins ◽

Low Density ◽

Lipoprotein Receptor ◽

Hepatic Triglyceride ◽

Very Low Density Lipoproteins ◽

Density Lipoprotein Receptor ◽

Hepatic Triglyceride Lipase

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The carboxyl-terminal domain of lipoprotein lipase binds to the low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor (LRP) and mediates binding of normal very low density lipoproteins to LRP.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)37017-5 ◽

1994 ◽

Vol 269 (12) ◽

pp. 8653-8658 ◽

Cited By ~ 9

Author(s):

S.E. Williams ◽

I. Inoue ◽

H. Tran ◽

G.L. Fry ◽

M.W. Pladet ◽

...

Keyword(s):

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density Lipoproteins ◽

Low Density ◽

Lipoprotein Receptor ◽

Related Protein ◽

Very Low Density Lipoproteins ◽

Density Lipoprotein Receptor ◽

Carboxyl Terminal ◽

Lipoprotein Receptor Related Protein

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Uptake of canine beta-very low density lipoproteins by mouse peritoneal macrophages is mediated by a low density lipoprotein receptor.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)67367-3 ◽

1986 ◽

Vol 261 (24) ◽

pp. 11194-11201 ◽

Cited By ~ 20

Author(s):

C Koo ◽

M E Wernette-Hammond ◽

T L Innerarity

Keyword(s):

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Peritoneal Macrophages ◽

Low Density Lipoproteins ◽

Low Density ◽

Lipoprotein Receptor ◽

Very Low Density Lipoproteins ◽

Low Density Lipoprotein Receptor ◽

Density Lipoprotein Receptor ◽

Mouse Peritoneal Macrophages

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Transport of beta-very low density lipoproteins and chylomicron remnants by macrophages is mediated by the low density lipoprotein receptor pathway.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)61656-4 ◽

1987 ◽

Vol 262 (5) ◽

pp. 2316-2325 ◽

Cited By ~ 18

Author(s):

J.L. Ellsworth ◽

F.B. Kraemer ◽

A.D. Cooper

Keyword(s):

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density Lipoproteins ◽

Low Density ◽

Lipoprotein Receptor ◽

Very Low Density Lipoproteins ◽

Low Density Lipoprotein Receptor ◽

Density Lipoprotein Receptor ◽

Chylomicron Remnants

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Increased removal of beta-very low density lipoproteins after ethinyl estradiol is associated with increased mRNA levels for hepatic lipase, lipoprotein lipase, and the low density lipoprotein receptor in Watanabe heritable hyperlipidemic rabbits.

Arteriosclerosis and Thrombosis A Journal of Vascular Biology ◽

10.1161/01.atv.11.6.1652 ◽

1991 ◽

Vol 11 (6) ◽

pp. 1652-1659 ◽

Cited By ~ 14

Author(s):

P N Demacker ◽

B Staels ◽

A F Stalenhoef ◽

J Auwerx

Keyword(s):

Ethinyl Estradiol ◽

Hepatic Lipase ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density Lipoproteins ◽

Low Density ◽

Lipoprotein Receptor ◽

Mrna Levels ◽

Very Low Density Lipoproteins ◽

Density Lipoprotein Receptor

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Cellular catabolism of normal very low density lipoproteins via the low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor is induced by the C-terminal domain of lipoprotein lipase.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)32409-2 ◽

1994 ◽

Vol 269 (27) ◽

pp. 18001-18006 ◽

Cited By ~ 8

Author(s):

D.A. Chappell ◽

I. Inoue ◽

G.L. Fry ◽

M.W. Pladet ◽

S.L. Bowen ◽

...

Keyword(s):

Lipoprotein Lipase ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density Lipoproteins ◽

Low Density ◽

Lipoprotein Receptor ◽

Related Protein ◽

Very Low Density Lipoproteins ◽

Density Lipoprotein Receptor ◽

Lipoprotein Receptor Related Protein

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Stimulation of thein VivoProduction of Very Low Density Lipoproteins by Apolipoprotein E Is Independent of the Presence of the Low Density Lipoprotein Receptor

Journal of Biological Chemistry ◽

10.1074/jbc.m106396200 ◽

2001 ◽

Vol 276 (44) ◽

pp. 40693-40697 ◽

Cited By ~ 16

Author(s):

Bas Teusink ◽

Arjen R. Mensenkamp ◽

Hans van der Boom ◽

Folkert Kuipers ◽

Ko Willems van Dijk ◽

...

Keyword(s):

Apolipoprotein E ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density Lipoproteins ◽

Low Density ◽

Lipoprotein Receptor ◽

Very Low Density Lipoproteins ◽

Low Density Lipoprotein Receptor ◽

Density Lipoprotein Receptor ◽

Stimulation Of

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Alterations in Thyroid Status Modulate Apolipoprotein, Hepatic Triglyceride Lipase, and Low Density Lipoprotein Receptor in Rats*

Endocrinology ◽

10.1210/endo-127-3-1144 ◽

1990 ◽

Vol 127 (3) ◽

pp. 1144-1152 ◽

Cited By ~ 80

Author(s):

BART STAEL ◽

ARIE VAN TOL ◽

LAWRENCE CHAN ◽

HANS WILL ◽

GUIDO VERHOEVEN ◽

...

Keyword(s):

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Hepatic Triglyceride ◽

Thyroid Status ◽

Low Density Lipoprotein Receptor ◽

Triglyceride Lipase ◽

Density Lipoprotein Receptor ◽

Hepatic Triglyceride Lipase

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Apolipoprotein C-I modulates the interaction of apolipoprotein E with beta-migrating very low density lipoproteins (beta-VLDL) and inhibits binding of beta-VLDL to low density lipoprotein receptor-related protein.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)45726-2 ◽

1990 ◽

Vol 265 (36) ◽

pp. 22453-22459 ◽

Cited By ~ 17

Author(s):

K H Weisgraber ◽

R W Mahley ◽

R C Kowal ◽

J Herz ◽

J L Goldstein ◽

...

Keyword(s):

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density Lipoproteins ◽

Low Density ◽

Lipoprotein Receptor ◽

Related Protein ◽

Very Low Density Lipoproteins ◽

Apolipoprotein C ◽

Density Lipoprotein Receptor ◽

Lipoprotein Receptor Related Protein

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In the absence of the low density lipoprotein receptor, human apolipoprotein C1 overexpression in transgenic mice inhibits the hepatic uptake of very low density lipoproteins via a receptor-associated protein-sensitive pathway.

Journal of Clinical Investigation ◽

10.1172/jci119036 ◽

1996 ◽

Vol 98 (10) ◽

pp. 2259-2267 ◽

Cited By ~ 77

Author(s):

M C Jong ◽

V E Dahlmans ◽

P J van Gorp ◽

K W van Dijk ◽

M L Breuer ◽

...

Keyword(s):

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Hepatic Uptake ◽

Low Density Lipoproteins ◽

Low Density ◽

Lipoprotein Receptor ◽

Very Low Density Lipoproteins ◽

Receptor Associated Protein ◽

Human Apolipoprotein ◽

Density Lipoprotein Receptor

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Low density lipoprotein-receptor plays a major role in the binding of very low density lipoproteins and their remnants on HepG2 cells

The International Journal of Biochemistry & Cell Biology ◽

10.1016/s1357-2725(99)00014-x ◽

1999 ◽

Vol 31 (6) ◽

pp. 695-705 ◽

Cited By ~ 5

Author(s):

To Quyen Truong ◽

Louise Falstrault ◽

Caroline Tremblay ◽

Louise Brissette

Keyword(s):

Hepg2 Cells ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density Lipoproteins ◽

Low Density ◽

Lipoprotein Receptor ◽

Very Low Density Lipoproteins ◽

Low Density Lipoprotein Receptor ◽

Density Lipoprotein Receptor

Download Full-text