Varying susceptibility to myocardial infarction among C57BL/6 mice of different genetic background

2003 ◽  
Vol 35 (6) ◽  
pp. 705-708 ◽  
Author(s):  
D Gorog
Keyword(s):  
Myocardial Infarction ◽  
Genetic Background ◽  
Different Genetic Background

scholarly journals Identification and Characterization of Novel Maize Mirnas Involved in Different Genetic Background

2015 ◽  
Vol 11 (7) ◽  
pp. 781-793 ◽  
Author(s):  
Lei Sheng ◽  
Wenbo Chai ◽  
Xuefeng Gong ◽  
Lingyan Zhou ◽  
Ronghao Cai ◽  
...  
Keyword(s):  
Genetic Background ◽  
Different Genetic Background ◽  
Identification And Characterization

Functionality of cryopreserved juvenile ovaries from mutant mice in different genetic background strains after allotransplantation

Cryobiology ◽  
2010 ◽  
Vol 60 (2) ◽  
pp. 129-137 ◽  
Author(s):  
Kuo-Yu Huang ◽  
Suzanna A. de Groot ◽  
Henri Woelders ◽  
Gijsbertus T.J. van der Horst ◽  
Axel P.N. Themmen ◽  
...  
Keyword(s):  
Genetic Background ◽  
Mutant Mice ◽  
Different Genetic Background

scholarly journals Phenotypic and clonal stability of antigen-inexperienced memory-like T cells across the genetic background, hygienic status, and aging

2020 ◽  
Author(s):  
Alena Moudra ◽  
Veronika Niederlova ◽  
Jiri Novotny ◽  
Lucie Schmiedova ◽  
Jan Kubovciak ◽  
...  
Keyword(s):  
Gene Expression ◽  
T Cells ◽  
Genetic Background ◽  
Expression Profiles ◽  
Bacterial Colonization ◽  
Gene Expression Profiles ◽  
Inbred Strains ◽  
Microbial Colonization ◽  
Independent Manner ◽  
Different Genetic Background

AbstractAntigen-inexperienced memory-like T (AIMT) cells are functionally unique T cells representing one of the two largest subsets of murine CD8+ T cells. However, differences between laboratory inbred strains, insufficient data from germ-free mice, a complete lack of data from feral mice, and unclear relationship between AIMT cells formation during aging represent major barriers for better understanding of their biology. We performed a thorough characterization of AIMT cells from mice of different genetic background, age, and hygienic status by flow cytometry and multi-omics approaches including analyses of gene expression, TCR repertoire, and microbial colonization. Our data showed that AIMT cells are steadily present in mice independently of their genetic background and hygienic status. Despite differences in their gene expression profiles, young and aged AIMT cells originate from identical clones. We identified that CD122 discriminates two major subsets of AIMT cells in a strain-independent manner. Whereas thymic CD122LOW AIMT cells (innate memory) prevail only in young animals with high thymic IL-4 production, peripheral CD122HIGH AIMT cells (virtual memory) dominate in aged mice. Co-housing with feral mice changed the bacterial colonization of laboratory strains, but had only minimal effects on the CD8+ T-cell compartment including AIMT cells.

Isolation of telomere DNA from Neurospora crassa

1987 ◽  
Vol 7 (9) ◽  
pp. 3168-3177
Author(s):  
M G Schechtman
Keyword(s):  
Linkage Group ◽  
Neurospora Crassa ◽  
Genetic Background ◽  
Type Strain ◽  
Wild Type Strain ◽  
The Other ◽  
Wild Type ◽  
Oak Ridge ◽  
Entire Chromosome ◽  
Different Genetic Background

The most distal known gene on Neurospora crassa linkage group VR, his-6, was cloned. A genomic walk resulted in isolation of the telomere at VR. It was obtained from a library in which the endmost nucleotides of the chromosome had not been removed by nuclease treatment before being cloned, and mapping indicates that the entire chromosome end has probably been cloned. Sequences homologous to the terminal 2.5 kilobases of DNA from VR from these Oak Ridge N. crassa strains are found at other sites in the genome. To characterize these sites, I crossed an Oak Ridge-derived his-6 strain with a wild-type strain of different genetic background (Mauriceville) and characterized the hybridization patterns seen in the progeny. It appears that the sequences homologous to the VR terminus are found at genetically different sites in the two parental strains, and no hybridization to the VR telomere from Mauriceville was detected. The other genomic copies identified in the Oak Ridge parent were not telomeres. I suggest that any repeating sequence blocks found immediately adjacent to the VR terminus in Oak Ridge strains must be small and that the repeating element identified in that background may be an N. crassa transposable element integrated near the the chromosome end at VR.

scholarly journals Autophagy-dependent toxicity of amino-functionalized nanoparticles in ovarian cancer cells

2019 ◽  
Vol 7 (35) ◽  
pp. 5376-5391 ◽  
Author(s):  
Christian Seca ◽  
Alessandra Ferraresi ◽  
Suratchanee Phadngam ◽  
Chiara Vidoni ◽  
Ciro Isidoro
Keyword(s):  
Ovarian Cancer ◽  
Cancer Cells ◽  
Genetic Background ◽  
Ovarian Cancer Cells ◽  
Differential Impact ◽  
Functionalized Nanoparticles ◽  
Different Genetic Background

Polystyrene NH2-NPs induce toxicity through a differential impact on autophagy machinery in ovarian cancer cells with a different genetic background.

Structural and thermodynamic properties of rice starches with different genetic background

2007 ◽  
Vol 41 (5) ◽  
pp. 534-547 ◽  
Author(s):  
Dasha A. Koroteeva ◽  
Valentina I. Kiseleva ◽  
Aleksey V. Krivandin ◽  
Olga V. Shatalova ◽  
Wioletta Błaszczak ◽  
...  
Keyword(s):  
Thermodynamic Properties ◽  
Genetic Background ◽  
Different Genetic Background

Effect of level of feed intake on the performance and carcass composition of growing pigs

1972 ◽  
Vol 14 (2) ◽  
pp. 199-208 ◽  
Author(s):  
R. S. Barber ◽  
R. Braude ◽  
K. G. Mitchell ◽  
R. J. Pittman
Keyword(s):  
Feed Intake ◽  
Genetic Background ◽  
Live Weight ◽  
Growing Pigs ◽  
Carcass Composition ◽  
Large White ◽  
Enzootic Pneumonia ◽  
Litter Mate ◽  
Different Genetic Background ◽  
Different Levels

SUMMARY1. Twelve blocks of six enzootic-pneumonia-free Large White litter-mate pigs were individually fed, wet, from 20 to 92 kg live weight on six different levels of feed intake. Four groups were fed according to scales based on live weight and two were fed on a ‘semi-ad libitum’ system. One of the scales used was based on the ARC (1967) recommendations.2. Pigs on ‘semi-ad libitum’ feeding grew significantly faster than those on scale feeding although the feed: gain ratios were similar. Differences in performance between the four scale-fed groups were relatively small.3. Although treatment differences in carcass measurements were in the main small, the commercial grading results favoured the carcasses from the scale-fed pigs. The firmness of backfat assessed by thumb pressure was reduced as the level of feeding was increased.4. The results were compared with those obtained in a similar trial carried out at Shinfield in 1957 using pigs of a completely different genetic background. The general conclusions reached were similar in the two trials, that to obtain the most satisfactory overall results some form of controlled scale-feeding was necessary.

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