0178 Proglumide, a cholecystokinin antagonist, attenuates lithium-pilocarpine induced status epilepticus in immature rats

2005 ◽  
Vol 238 ◽  
pp. S145
Keyword(s):  
Status Epilepticus ◽  
Cholecystokinin Antagonist ◽  
Immature Rats

scholarly journals Status Epilepticus Causes Necrotic Damage in the Mediodorsal Nucleus of the Thalamus in Immature Rats

2001 ◽  
Vol 21 (10) ◽  
pp. 3593-3599 ◽  
Author(s):  
Hana Kubová ◽  
Rastislav Druga ◽  
Katarzyna Lukasiuk ◽  
Lucie Suchomelová ◽  
Renata Haugvicová ◽  
...  
Keyword(s):  
Status Epilepticus ◽  
Mediodorsal Nucleus ◽  
Immature Rats

scholarly journals Status Epilepticus in Immature Rats Is Associated with Oxidative Stress and Mitochondrial Dysfunction

2016 ◽  
Vol 10 ◽  
Author(s):  
Jaroslava Folbergrová ◽  
Pavel Ješina ◽  
Hana Kubová ◽  
Rastislav Druga ◽  
Jakub Otáhal
Keyword(s):  
Oxidative Stress ◽  
Status Epilepticus ◽  
Mitochondrial Dysfunction ◽  
Immature Rats

Persistent reduction of hippocampal glutamine synthetase expression after status epilepticus in immature rats

2014 ◽  
Vol 40 (12) ◽  
pp. 3711-3719 ◽  
Author(s):  
W. Saskia van der Hel ◽  
Ellen V. S. Hessel ◽  
Ineke W. M. Bos ◽  
Sandra D. Mulder ◽  
Suzanne A. M. W. Verlinde ◽  
...  
Keyword(s):  
Status Epilepticus ◽  
Glutamine Synthetase ◽  
Immature Rats

Effects of pentylenetetrazole-induced status epilepticus on behavior, emotional memory and learning in immature rats

2005 ◽  
Vol 6 (4) ◽  
pp. 537-542 ◽  
Author(s):  
Füsun Erdoğan ◽  
Asuman Gölgeli ◽  
Ayşegül Küçük ◽  
Fehim Arman ◽  
Yahya Karaman ◽  
...  
Keyword(s):  
Status Epilepticus ◽  
Emotional Memory ◽  
Memory And Learning ◽  
Immature Rats

Aminophylline exacerbates status epilepticus-induced neuronal damages in immature rats: a morphological, motor and behavioral study

2002 ◽  
Vol 49 (3) ◽  
pp. 218-225 ◽  
Author(s):  
Pi-Lien Hung ◽  
Ming-Chi Lai ◽  
San Nan Yang ◽  
Chih-Lu Wang ◽  
Chia-Wei Liou ◽  
...  
Keyword(s):  
Status Epilepticus ◽  
Behavioral Study ◽  
Immature Rats

Magnolia officinalis Reduces Inflammation and Damage Induced by Recurrent Status Epilepticus in Immature Rats

2020 ◽  
Vol 26 (12) ◽  
pp. 1388-1401
Author(s):  
Angélica Vega-García ◽  
Luisa Rocha ◽  
Rosalinda Guevara-Guzmán ◽  
Christian Guerra-Araiza ◽  
Iris Feria-Romero ◽  
...  
Keyword(s):  
Status Epilepticus ◽  
Neuronal Loss ◽  
Preventive Treatment ◽  
Post Treatment ◽  
Sprague Dawley ◽  
Neuroprotective Effects ◽  
Sprague Dawley Rats ◽  
Immature Rats ◽  
Anti Inflammatory ◽  
Magnolia Officinalis

Background: Neuroinflammation induced in response to damage caused by status epilepticus (SE) activates the interleukin (IL)1-β pathway and proinflammatory proteins that increase vulnerability to the development of spontaneous seizure activity and/or epilepsy. Objectives: The study aimed to assess the short-term anti-inflammatory and neuroprotective effects of Magnolia officinalis (MO) on recurrent SE in immature rats. Methods: Sprague-Dawley rats at PN day 10 were used; n = 60 rats were divided into two control groups, SHAM and KA, and two experimental groups, MO (KA-MO) and Celecoxib (KA-Clbx). The anti-inflammatory effect of a single dose of MO was evaluated at 6 and 24 hr by Western blotting and on day 30 PN via a subchronic administration of MO to assess neuronal preservation and hippocampal gliosis by immunohistochemistry for NeunN and GFAP, respectively. Results: KA-MO caused a decrease in the expression of IL1-β and Cox-2 at 6 and 24 h post-treatment, a reduction in iNOS synthase at 6 and 24 hr post-treatment and reduced neuronal loss and gliosis at postnatal day 30, similar to Clbx. Conclusion: The results indicating that Magnolia officinalis is an alternative preventive treatment for early stages of epileptogenesis are encouraging.

scholarly journals Expression and functional analysis of lncRNAs in the hippocampus of immature rats with status epilepticus

2020 ◽  
Vol 24 (1) ◽  
pp. 149-159 ◽  
Author(s):  
Jing Gan ◽  
Lingyi Huang ◽  
Yi Qu ◽  
Rong Luo ◽  
Qianyun Cai ◽  
...  
Keyword(s):  
Functional Analysis ◽  
Status Epilepticus ◽  
Immature Rats
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