scholarly journals Early and late postoperative studies in coronary arterial lesions resulting from Kawasaki’s disease in children

1982 ◽  
Vol 84 (2) ◽  
pp. 224-229 ◽  
Author(s):  
Kozo Suma ◽  
Yasuo Takeuchi ◽  
Kenji Shiroma ◽  
Takayuki Tsuji ◽  
Kenji Inoue ◽  
...  
Circulation ◽  
1997 ◽  
Vol 96 (6) ◽  
pp. 2078-2078 ◽  
Author(s):  
Martha L. Clabby ◽  
Angela M. Sharkey

2009 ◽  
Vol 4 ◽  
pp. S75
Author(s):  
Osama L. Gomaa ◽  
Tarinee Tangcharoen ◽  
Thomas Kokocinski ◽  
Bernhard Schnackenburg ◽  
Fleck Eckart ◽  
...  

Circulation ◽  
2015 ◽  
Vol 131 (suppl_2) ◽  
Author(s):  
Olga Bockeria ◽  
Galina Lyskina ◽  
Olga Shirinskaya ◽  
Anna Satyukova ◽  
Nina Gagarina

Background: Kawasaki’s disease (KD) is an acute systemic vasculitis in childhood. Lesion in the coronary arteries (CA) causes an acute or chronic ischemia, myocardial infarction and sudden death. Materials and Methods: The study included 189 children with KD for the period of 9 years (2004 - 2013). The age of the patients at the time of the acute stage of the disease was 1 month - 12 years 8 months . Boys and girls ratio was 1.8:1. 92% of the children were ill at the age of up to 5 years. Mean follow-up period was 15,8 months. We performed coronary angiography by CT scan in 14 children and by catheter in 9 children in CCVS. Echo was done in all 189 children. Results: Aneurysms of CA were found in 59 (31.2%) patients according to echocardiography data. The frequency of aneurysm formation in children first year of life was higher than in children older than 1 year (41.3% and 29.3%). Thirty eight (20%) patients had multiple aneurysms. Small aneurysms with a diameter less than 5 mm were found in 16.4% of patients, average (5 - 8 mm) - in 9%, giant (greater than 8 mm) - in 5.8% of patients. Transient CA ectasia was diagnosed in 13.2% of children. Sensitivity of echocardiography in diagnosis of CA aneurysms was 88.5% in comparison with MSCT coronary angiography, specificity - 92.3%. Mean aneurysms' diameter measured by ECHO was 7,1 ± 3,3 mm, while CT contrast study revealed 7,3 ± 3,1 mm (p> 0.05). We found an involution of 40.2% of aneurysms during follow-up. Thrombi were found in 8 of 11 patients with giant aneurysms by echocardiography. Five thrombi disappeared after conservative therapy, 2 increased and occluded the RCA. CA stenosis greater than 75% was revealed in 2 patients with giant aneurysms in 2 years 7 months and in 3.5 months after manifestation of KD by using coronary arteriography. Conclusion: Kawasaki’s disease is a frequent cause of aneurysms, thrombosis and stenosis in coronary arteries in early childhood. Giant aneurysms often predispose to occlusion of the CA. Echocardiography is a highly specific and sensitive method for the visualization of CA aneurysms and thrombi. Other methods are useful when distinguishing stenosis and thrombosis in small CA is required.


Author(s):  
Brian W. McCrindle

Kawasaki’s disease is an acute, self-limited, inflammatory vasculitis of unknown aetiology, with a peak incidence under 5 years of age. Clinical features—the diagnosis is made in the presence of persistent fever for 5 days or more and at least four of the following five clinical signs: (1) nonpurulent conjunctivitis, (2) oropharyngeal inflammation, (3) cervical lymphadenopathy, (4) polymorphous exanthem, and (5) erythema of the palms and soles with subsequent desquamation. Incomplete presentations occur in approximately 25% of patients. The primary complications are cardiac, with coronary artery dilation and aneurysms evident in approximately 15 to 25% of untreated patients....


Cardiology ◽  
2003 ◽  
Vol 99 (2) ◽  
pp. 113-114
Author(s):  
David S. Bromet ◽  
Sandeep Nathan ◽  
Dee Ann Rivera ◽  
Nimit Aggarwal ◽  
James E. Calvin ◽  
...  

PEDIATRICS ◽  
2008 ◽  
Vol 121 (Supplement 2) ◽  
pp. S93.2-S94
Author(s):  
Akiko Hamaoka ◽  
Ayumi Niboshi ◽  
Tomoyo Yahata ◽  
Seiichiro Ozawa ◽  
Isao Shiraishi ◽  
...  

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