Serum acid phosphatase activity in the diagnosis of carcinoma of the prostate

Pathology ◽  
1977 ◽  
Vol 9 (1) ◽  
pp. 85
Author(s):  
R.D. McEvoy ◽  
P.J. Phillips ◽  
R. Rowland ◽  
J.-B. Edwards ◽  
R. Bais
Keyword(s):  
Acid Phosphatase ◽  
Phosphatase Activity ◽  
Acid Phosphatase Activity ◽  
Carcinoma Of The Prostate ◽  
Serum Acid Phosphatase

Acid phosphatase in Gaucher's disease.

1980 ◽  
Vol 26 (3) ◽  
pp. 371-382
Author(s):  
D B Robinson ◽  
R H Glew
Keyword(s):  
Acid Phosphatase ◽  
Phosphatase Activity ◽  
Acid Phosphatase Activity ◽  
Purification And Characterization ◽  
Gaucher's Disease ◽  
Gaucher’S Disease ◽  
Intracellular Location ◽  
Increased Activity ◽  
Serum Acid Phosphatase

Abstract Increased acid phosphatase activity in the serum and tissues of patients with Gaucher's disease has now been recognized for two decades, but as yet no relation has been established between the enzyme and the etiology and progress of the disease. Here, we review results obtained by various investigators, ranging from a consideration of the methods used for the evaluation of serum acid phosphatase in Gaucher's disease to the most recent findings regarding the purification and characterization of two acid phosphatase isoenzymes from the spleen from patients with Gaucher's disease. We also discuss the intracellular location of tissue acid phosphatase in patients with Gaucher's disease and its contribution to the increased activity in serum.

scholarly journals Serum Acid Phosphatase Activity in Diabetes Mellitus

2014 ◽  
Vol 13 (1) ◽  
pp. 26-30
Author(s):  
Sonam Tashi Dolma ◽  
◽  
Davina Hijam ◽  
David Gangte ◽  
Ng. Arunkumar ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Acid Phosphatase ◽  
Phosphatase Activity ◽  
Acid Phosphatase Activity ◽  
Serum Acid Phosphatase

Automated Determination of Acid Phosphatase

1965 ◽  
Vol 11 (11) ◽  
pp. 998-1008 ◽  
Author(s):  
Bernard Klein ◽  
Joseph Auerbach ◽  
Stanley Morgenstern
Keyword(s):  
Acid Phosphatase ◽  
Phosphatase Activity ◽  
Acid Phosphatase Activity ◽  
Biological Materials ◽  
Flow Diagram ◽  
Animal Origin ◽  
Phenolic Substances ◽  
Automated Determination ◽  
Serum Acid Phosphatase

Abstract A procedure is presented for the automated determination of acid phosphatase activity in biological materials from either plant or animal origin. The Technicon N-7 flow diagram has been simplified, and the reagents for the measurement of enzymatically produced phenolic substances have been modified without loss of range or sensitivity. Both phenylphosphate and α-naphthylphosphate, introduced by Babson et al. (2, 3) for serum acid phosphatase, may be used as substrates. The Emerson reaction (alkaline aminoantipyrine and ferricyanide) with α-naphthol forms a more stable and reproducible color than the coupled product with tetrazotized o-dianisidine (Babson). Supporting data for these modifications are included.

Automated Determination of Acid Phosphatase

1966 ◽  
Vol 12 (4) ◽  
pp. 226-233 ◽  
Author(s):  
Bernard Klein ◽  
Morris Oklander ◽  
Stanley Morgenstern
Keyword(s):  
Acid Phosphatase ◽  
Human Serum ◽  
Phosphatase Activity ◽  
Acid Phosphatase Activity ◽  
Prostatic Acid Phosphatase ◽  
Biological Materials ◽  
Automated System ◽  
Automated Determination ◽  
Serum Acid Phosphatase

Abstract A procedure is presented for the automated determination of acid phosphatase activity in biological materials using the Robot Chemist. Although either phenylphosphate and α-naphthylphosphate may be used as substrate in this analysis, the procedure is described in detail for serum acid phosphatase using α-naphthylphosphate in 0.1 M citrate, pH 5.2, since this substrate is more selective for prostatic acid phosphatase in human serum. Enzymically generated aα- naphthol is determined by the Emerson reaction (alkaline aminoantipyrine and ferricyanide), modified for use with this automated system. Correlations are presented between the results obtained on the Robot Chemist and the identical procedure developed for the AutoAnalyzer.

Aqueous extract of Securidaca longepedunculata root induce redox imbalance in male rat liver and kidney

2010 ◽  
Vol 29 (8) ◽  
pp. 679-688 ◽  
Author(s):  
TO Ajiboye ◽  
AK Salau ◽  
MT Yakubu ◽  
AT Oladiji ◽  
MA Akanji ◽  
...  
Keyword(s):  
Acid Phosphatase ◽  
Phosphatase Activity ◽  
Rat Liver ◽  
Aqueous Extract ◽  
Acid Phosphatase Activity ◽  
Male Rat ◽  
Antioxidant Systems ◽  
Liver And Kidney ◽  
Securidaca Longepedunculata ◽  
Serum Acid Phosphatase

The effect of aqueous extract of Securidaca longepedunculata root on redox homeostasis in male rat liver and kidney was investigated. Rats were grouped into four: A, B, C and D, where A (the control) received orally 1 mL of distilled water; B, C and D (test groups) received orally 200, 400 and 800 mg/kg body weight of the extract, respectively, for 28 days. Extract administration significantly reduced (p < .05) alkaline phosphatase activity in the liver and kidney with corresponding increases in the serum. Acid phosphatase activity increased significantly (p < .05) in the liver and kidney, while there was no significant change (p > .05) in the serum acid phosphatase activity. There was also significant decrease (p < .05) in the activities of superoxide dismutase, catalase, glutathione peroxidase and glutathione reductase in the liver and kidney. Liver and kidney levels of GSH, vitamins C and E were also significantly reduced (p < .05). Serum malonidialdehyde and lipid hydroperoxide increased significantly (p < .05) in all the extract-treated groups. The available data from this study revealed that aqueous extract of S. longepedunculata root exerted its toxicity in the animals by depleting the antioxidant systems. This may consequently expose the cells and cellular macromolecules to oxidative damage by reactive oxygen species generated either from the metabolism of the extract or other in vivo means.

Raised serum acid phosphatase activity in an adult with hypophosphatasia

1983 ◽  
Vol 6 (S2) ◽  
pp. 103-104 ◽  
Author(s):  
S. J. Iqbal ◽  
W. H. Taylor ◽  
N. B. Roberts ◽  
J. M. Darlow
Keyword(s):  
Acid Phosphatase ◽  
Phosphatase Activity ◽  
Acid Phosphatase Activity ◽  
Serum Acid Phosphatase

Stabilization and Preservation of Serum Prostatic Acid Phosphatase Activity

1965 ◽  
Vol 11 (10) ◽  
pp. 943-950 ◽  
Author(s):  
Richard P Doe ◽  
George T Mellinger ◽  
Ulysses S Seal
Keyword(s):  
Acid Phosphatase ◽  
Phosphatase Activity ◽  
Acid Phosphatase Activity ◽  
Prostatic Acid Phosphatase ◽  
Original Activity ◽  
Satisfactory Method ◽  
Effects Of Ph ◽  
The Stability ◽  
Serum Acid Phosphatase

Abstract The effects of pH and temperature of storage on the stability of the prostatic fraction of serum acid phosphatase activity have been studied in order to provide a satisfactory method for the preservation of activity in serums shipped from other hospitals. Addition of citrate tablets of a composition to buffer the serums at pH 6.2 was found to preserve the original activity at 25° for at least 7 days. These results were validated on a series of serums, subdivided into control and citrate-containing aliquots, shipped from the participating hospitals.

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