Black widow spider toxins: the present and the future

Toxicon ◽  
1998 ◽  
Vol 36 (11) ◽  
pp. 1693-1701 ◽  
Author(s):  
E.V. Grishin
Keyword(s):  
Black Widow ◽  
Black Widow Spider ◽  
Spider Toxins ◽  
The Future ◽  
Widow Spider

The multiple actions of black widow spider toxins and their selective use in neurosecretion studies

Toxicon ◽  
2004 ◽  
Vol 43 (5) ◽  
pp. 527-542 ◽  
Author(s):  
Y.A. Ushkaryov ◽  
K.E. Volynski ◽  
A.C. Ashton
Keyword(s):  
Black Widow ◽  
Black Widow Spider ◽  
Spider Toxins ◽  
Widow Spider

Female black widow spider mates with and eats many males

2021 ◽  
Vol 250 (3333) ◽  
pp. 11
Author(s):  
Christa Lesté-Lasserre
Keyword(s):  
Black Widow ◽  
Black Widow Spider ◽  
Widow Spider

Properties of spontaneous potentials at denervated motor endplates of the frog

1976 ◽  
Vol 194 (1115) ◽  
pp. 195-210 ◽  
Keyword(s):  
Schwann Cell ◽  
Time Course ◽  
Experimental Treatment ◽  
Spider Venom ◽  
Black Widow ◽  
Motor Endplates ◽  
Black Widow Spider ◽  
Ringer’S Solution ◽  
Black Widow Spider Venom ◽  
Widow Spider

Some properties of spontaneous miniature potentials at denervated frog motor endplates (Schwann cell-min. e. p. ps) have been investigated. Schwann cell-min. e. p. ps showed a slower and more variable time course than min. e. p. ps at inneryated endplates. The occurrence of Schwann cell-min. e. p. ps usually obeyed Poisson statistics and in the absence of experimental treatment their mean frequency remained stable for several hours. Schwann cell-min. e. p. p. frequency increased with increasing temperature. A logarithmic relation was observed with a mean Q 10 of 4.87 ± 0.37. In other experiments a Q 10 of 9.50 ± 0.63 was found for min. e. p. ps at innervated endplates. Lanthanum and manganese ions, black widow spider venom, ethanol, diamide, ouabain, theophylline and acid Ringer’s solution, all of which increased normal min. e. p. p. frequency, failed to raise the frequency of Schwann cell-min. e. p. ps. Lanthanum, ethanol, ouabain and low pH depressed the frequency, while black widow spider venom, diamide, theophyline and manganese were without significant effect. Adenosine, which depresses min. e. p. p. frequency at innervated endplates, had no effect on spontaneous miniature potentials at denervated endplates. Removal of Ca 2+ from the external medium reduced the frequency of Schwann min. e. p. ps; and a decrease was also seen in one experiment where the Ca 2+ concentration was raised from 1.8 to 10 mM. Diluting the Ringer’s solution raised Schwann cell-min. e. p. p. frequency transiently. This increase resulted from a reduction in osmolarity, not in the ionic strength, of the medium.

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