Chapter Two A genomics approach to plant one-carbon metabolism

Author(s):  
Sanja Roje ◽  
Andrew D. Hanson
2010 ◽  
Vol 80 (45) ◽  
pp. 319-329 ◽  
Author(s):  
Allyson A. West ◽  
Marie A. Caudill

Folate and choline are water-soluble micronutrients that serve as methyl donors in the conversion of homocysteine to methionine. Inadequacy of these nutrients can disturb one-carbon metabolism as evidenced by alterations in circulating folate and/or plasma homocysteine. Among common genetic variants that reside in genes regulating folate absorptive and metabolic processes, homozygosity for the MTHFR 677C > T variant has consistently been shown to have robust effects on status markers. This paper will review the impact of genetic variants in folate-metabolizing genes on folate and choline bioefficacy. Nutrient-gene and gene-gene interactions will be considered along with the need to account for these genetic variants when updating dietary folate and choline recommendations.


Proceedings ◽  
2019 ◽  
Vol 8 (1) ◽  
pp. 19
Author(s):  
Nicola Gillies ◽  
Amber M. Milan ◽  
Pankaja Sharma ◽  
Brenan Durainayagam ◽  
Sarah M. Mitchell ◽  
...  

Background: Maintaining optimal status of folate and metabolically [...]


2021 ◽  
Vol 21 (4) ◽  
pp. 206-206
Author(s):  
Felix Clemens Richter ◽  
Alexander J. Clarke

Toxicology ◽  
2021 ◽  
pp. 152803
Author(s):  
Ahlam Abuawad ◽  
Anne K. Bozack ◽  
Roheeni Saxena ◽  
Mary V. Gamble

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