In vivo study of a calcium phosphate cement consisting of α-tricalcium phosphate/dicalcium phosphate dibasic/tetracalcium phosphate monoxide

Biomaterials ◽  
1997 ◽  
Vol 18 (2) ◽  
pp. 147-151 ◽  
Author(s):  
K. Kurashina ◽  
H. Kurita ◽  
A. Kotani ◽  
H. Takeuchi ◽  
M. Hirano
2010 ◽  
Vol 2010 ◽  
pp. 1-14 ◽  
Author(s):  
Rania M. Khashaba ◽  
Mervet M. Moussa ◽  
Donald J. Mettenburg ◽  
Frederick A. Rueggeberg ◽  
Norman B. Chutkan ◽  
...  

New polymeric calcium phosphate cement composites (CPCs) were developed. Cement powder consisting of 60 wt% tetracalcium phosphate, 30 wt% dicalcium phosphate dihydrate, and 10 wt% tricalcium phosphate was combined with either 35% w/w poly methyl vinyl ether maleic acid or polyacrylic acid to obtain CPC-1 and CPC-2. The setting time and compressive and diametral tensile strength of the CPCs were evaluated and compared with that of a commercial hydroxyapatite cement.In vitrocytotoxicity andin vivobiocompatibility of the two CPCs and hydroxyapatite cement were assessed. The setting time of the cements was 5–15 min. CPC-1 and CPC-2 showed significantly higher compressive and diametral strength values compared to hydroxyapatite cement. CPC-1 and CPC-2 were equivalent to Teflon controls after 1 week. CPC-1, CPC-2, and hydroxyapatite cement elicited a moderate to intense inflammatory reaction at 7 days which decreased over time. CPC-1 and CPC-2 show promise for orthopedic applications.


2020 ◽  
Vol 110 ◽  
pp. 280-288
Author(s):  
Sónia de Lacerda Schickert ◽  
John A Jansen ◽  
Ewald M. Bronkhorst ◽  
Jeroen JJP van den Beucken ◽  
Sander CG Leeuwenburgh

2016 ◽  
Vol 106 (1) ◽  
pp. 21-30 ◽  
Author(s):  
Niall W. Kent ◽  
Gordon Blunn ◽  
Natalia Karpukhina ◽  
Graham Davis ◽  
Roberta Ferro de Godoy ◽  
...  

2016 ◽  
Vol 16 (12) ◽  
pp. 1468-1477 ◽  
Author(s):  
Long Xin ◽  
Matthias Bungartz ◽  
Stefan Maenz ◽  
Victoria Horbert ◽  
Max Hennig ◽  
...  

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