scholarly journals NOVEL PREDICTORS OF LEFT VENTRICULAR SYSTOLIC FUNCTION RECOVERY IN PATIENTS WITH ST-ELEVATION MYOCARDIAL INFARCTION

2011 ◽  
Vol 57 (14) ◽  
pp. E1000
Author(s):  
Jose N. Codolosa
Keyword(s):  
Myocardial Infarction ◽  
Systolic Function ◽  
Left Ventricular Systolic Function ◽  
Left Ventricular ◽  
St Elevation Myocardial Infarction ◽  
Ventricular Systolic Function ◽  
Function Recovery ◽  
St Elevation

scholarly journals Re: Relationship between mean platelet volume and left ventricular systolic function in patients with metabolic syndrome and ST-elevation myocardial infarction

2012 ◽  
Vol 35 (2) ◽  
pp. 46
Author(s):  
Savaş Acikgoz ◽  
Meltem R Ege ◽  
Yesim Guray
Keyword(s):  
Myocardial Infarction ◽  
Metabolic Syndrome ◽  
Mean Platelet Volume ◽  
Systolic Function ◽  
Left Ventricular Systolic Function ◽  
Left Ventricular ◽  
St Elevation Myocardial Infarction ◽  
Platelet Volume ◽  
Ventricular Systolic Function ◽  
St Elevation

We have read with great interest the recently published report of Yazici et al. [1], which investigates the relationship between mean platelet volume (MPV) and left ventricular systolic function in patients with metabolic syndrome and ST-elevation myocardial infarction. The authors demonstrated that increased MPV on admission can be associated with the degree of left ventricle systolic depression in these patients. It has been reported that MPV, a measure of platelet size, reflects platelet function and activity...

scholarly journals Relationship between mean platelet volume and left ventricular systolic function in patients with metabolic syndrome and ST-elevation myocardial infarction

2011 ◽  
Vol 34 (6) ◽  
pp. 330 ◽  
Author(s):  
Huseyin U Yazici ◽  
Fatih Poyraz ◽  
Nihat Sen ◽  
Yusuf Tavil ◽  
Murat Turfan ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Metabolic Syndrome ◽  
Left Ventricle ◽  
Systolic Function ◽  
Left Ventricular Systolic Function ◽  
Left Ventricular ◽  
St Elevation Myocardial Infarction ◽  
Ventricular Systolic Function ◽  
St Elevation ◽  
Left Ventricle Systolic Function

Purpose: Mean platelet volume (MPV) is an indicator of platelet activation, which is a central process in the pathophysiology of coronary heart disease. Metabolic syndrome (MS) may lead to worsened left ventricular systolic function by causing recurrent thrombotic events and by aggravating systemic inflammation in the course of acute myocardial infarction. The present study was designed to investigate the relationship between MPV and left ventricular systolic function in patients with metabolic syndrome who had first ST-elevation myocardial infarction. Methods: MPV was measured on admission in 33 patients who had preserved left ventricle systolic function (mean age, 56.9±10.2 years) and in 48 patients who had depressed left ventricle systolic function (mean age, 57.9±10.5 years) with metabolic syndrome and first ST elevation myocardial infarction. Depressed left ventricle systolic function was defined as ≤50% ejection fraction value. MPV levels were compared in the two groups. Results: MPV was significantly higher in patients with depressed left ventricle systolic function in comparison with patients showing preserved left ventricle systolic function (p=0.02). Logistic regression analysis showed an independent relationship between MPV and deteriorated left ventricular systolic function, even after adjustment for potential confounders (1.08 (1.04-1.20), CI: 95%, p=0.02). Conclusions: Increased MPV on admission can be associated with degree of left ventricle systolic depression in patients with metabolic syndrome with first ST-elevation myocardial infarction. MPV may prove to be useful as a prognostic marker in patients with metabolic syndrome and ST elevation MI.

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