scholarly journals Hemodynamics of human carotid artery bifurcations: Computational studies with models reconstructed from magnetic resonance imaging of normal subjects

1998 ◽  
Vol 28 (1) ◽  
pp. 143-156 ◽  
Author(s):  
Jaques S. Milner ◽  
Jennifer A. Moore ◽  
Brian K. Rutt ◽  
David A. Steinman
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Carotid Artery ◽  
Normal Subjects ◽  
Computational Studies ◽  
Resonance Imaging ◽  
Human Carotid

scholarly journals Development of Molecular Magnetic Resonance Imaging Tools for Risk Stratification of Carotid Atherosclerotic Disease Using Dual-Targeted Microparticles of Iron Oxide

2021 ◽  
Author(s):  
Joyce M. S. Chan ◽  
Park Sung Jin ◽  
Michael Ng ◽  
Joanne Garnell ◽  
Chan Wan Ying ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Iron Oxide ◽  
High Risk ◽  
Magnetic Resonance ◽  
Carotid Artery ◽  
Risk Stratification ◽  
Stroke Prevention ◽  
Inflammatory Activity ◽  
Resonance Imaging ◽  
Inflammatory Status

AbstractIdentification of patients with high-risk asymptomatic carotid plaques remains a challenging but crucial step in stroke prevention. Inflammation is the key factor that drives plaque instability. Currently, there is no imaging tool in routine clinical practice to assess the inflammatory status within atherosclerotic plaques. We have developed a molecular magnetic resonance imaging (MRI) tool to quantitatively report the inflammatory activity in atherosclerosis using dual-targeted microparticles of iron oxide (DT-MPIO) against P-selectin and VCAM-1 as a smart MRI probe. A periarterial cuff was used to generate plaques with varying degree of phenotypes, inflammation and risk levels at specific locations along the same single carotid artery in an Apolipoprotein-E-deficient mouse model. Using this platform, we demonstrated that in vivo DT-MPIO-enhanced MRI can (i) target high-risk vulnerable plaques, (ii) differentiate the heterogeneity (i.e. high vs intermediate vs low-risk plaques) within the asymptomatic plaque population and (iii) quantitatively report the inflammatory activity of local plaques in carotid artery. This novel molecular MRI tool may allow characterisation of plaque vulnerability and quantitative reporting of inflammatory status in atherosclerosis. This would permit accurate risk stratification by identifying high-risk asymptomatic individual patients for prophylactic carotid intervention, expediting early stroke prevention and paving the way for personalised management of carotid atherosclerotic disease.

Role of magnetic resonance imaging in evaluating sphenoid sinus and internal carotid artery

2009 ◽  
Vol 123 (12) ◽  
pp. 1331-1337 ◽  
Author(s):  
H G Hatipoglu ◽  
M A Cetin ◽  
A Selvi ◽  
E Yuksel
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Carotid Artery ◽  
Internal Carotid Artery ◽  
Sphenoid Sinus ◽  
Carotid Arteries ◽  
Internal Carotid ◽  
Minimal Distance ◽  
Resonance Imaging ◽  
Internal Carotid Arteries

AbstractObjective:This study aimed to determine whether magnetic resonance imaging has a role in the evaluation of the sphenoid sinus and internal carotid artery. In addition, we aimed to establish reference measurements for the minimal distance between the internal carotid arteries.Method:The sphenoid sinuses and neighbouring internal carotid arteries of 90 patients were evaluated using sagittal T1-weighted and axial and coronal T2-weighted magnetic resonance images.Results:Sphenoid sinus pneumatisation was categorised as occipitosphenoidal (0 per cent), conchal (3.3 per cent), presellar (14.4 per cent) or sellar (82.2 per cent). The internal carotid artery protruded into the sphenoid sinus in 32.8 per cent, with a septum in 9.4 per cent. The incidence of sellar-type sphenoid sinus pneumatisation was higher in patients with protrusion of the internal carotid artery into the sphenoid sinus (p < 0.001). The incidence of presellar pneumatisation was higher in patients without internal carotid artery protrusion (p < 0.001). The minimal distance between the internal carotid arteries varied between 9.04 and 24.26 mm (mean, 15.94 mm).Conclusion:Magnetic resonance imaging can provide useful information about the sphenoid sinus and internal carotid artery, prior to endoscopic sphenoidotomy and trans-sphenoidal hypophysectomy.

scholarly journals Diagnosis of Carotid Artery Atheroma by Magnetic Resonance Imaging

2001 ◽  
Vol 65 (3) ◽  
pp. 139-144
Author(s):  
Katsuhiro Ono ◽  
Shigeru Watanabe ◽  
Yumiko Daimon ◽  
Hideki Sakurada ◽  
Miharu Urano ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Carotid Artery ◽  
Resonance Imaging

scholarly journals Pre- and Post-Operative Volume Estimation of Medulloblastoma Using Magnetic Resonance Imaging: A Stereological Study

2020 ◽  
Vol 17 (3) ◽  
Author(s):  
Farzaneh Dehghani ◽  
Seyede Fatemeh Hosseini ◽  
Reza Jalli ◽  
Fatemeh Karimi ◽  
Narges Sotoudeh ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Tumor Volume ◽  
Tumor Regression ◽  
Normal Subjects ◽  
Volume Estimation ◽  
Unbiased Estimation ◽  
Cerebellar Tumor ◽  
Resonance Imaging ◽  
Counting Approach

Background: Brain tumors are among the most lethal and devastating cancers. Medulloblastoma tumor is a common solid brain malignancy, arising in the posterior fossa. Stereological methods are used in combination with magnetic resonance imaging (MRI) to obtain unbiased estimation of the total volume of the structure of interest. Objectives: In the current study, we evaluated cerebellar tumor volume pre- and post-operative in patients suffering from meduloblastoma tumor using MRI and Cavalieri method. Patients and Methods: The study was performed on 16 subjects consisting of two groups of eight people including patient and control groups. Slide direction were in both sagittal and axial planes. Pre- and post-operative volume of medulloblastoma tumor were determined on MR scanning images using the point-counting approach of Cavalieri method. Results: The post-operative tumor volume in both sagittal (P = 0.028) and axial (P = 0.046) MR images was statistically reduced by 90% compared to the pre-operative volume. Moreover, the pre-operative volume of the cerebellum in patients increased by 38% in patients as compared to the normal subjects (P = 0.028). Conclusion: It could be concluded that MRI-estimated tumor-volume might be useful in evaluating the efficiency of surgical treatment and prognostication of tumor regression rate.

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