Suicide attempts and family history of suicide in schizophrenia

2003 ◽  
Vol 60 (1) ◽  
pp. 51
Author(s):  
F. Tremeau ◽  
P. Czobor ◽  
L. Staner ◽  
H. Correa ◽  
J.P. Macher
Keyword(s):  
Family History ◽  
Suicide Attempts ◽  
History Of

Psycho-Oncology: Cancer patients with past suicide attempts, or a family history of suicide.

2019 ◽  
Vol 37 (15_suppl) ◽  
pp. e23173-e23173
Author(s):  
Daniela Gercovich ◽  
Ernesto Gil Deza ◽  
Flavio Tognelli ◽  
Carlos Fernando Garcia Gerardi ◽  
Claudia Lorena Acuna ◽  
...  
Keyword(s):  
Family History ◽  
Cancer Patients ◽  
Cancer Diagnosis ◽  
Illicit Drugs ◽  
Suicide Attempts ◽  
The United States ◽  
Population Characteristics ◽  
History Of ◽  
Psychological Risk

e23173 Background: “The suicide rate in cancer patients is twice that observed in the general population in the United States” (JNCI vol 100, 24, page 1750, 2008). This paper focuses ona population with great psychological risk: cancer patients (Pt) with previous suicide attempts (SA) or a family history of suicide (FS); both grouped under SAFS for the purpose of this study. Methods: Between 9/26/2012 and 11/28/2018 all new patients (Pt) admitted to IOHM filled out a Past Medical History Form (PMHF) (ASCO 2013 ABST. e17539) with their preexisting clinical conditions. The database was locked and anonymized. Those with a history of SAFS before cancer diagnosis were selected. Results: Out of 15,617 Pt, 184 Pt (1.2%) were SAFS(141 Pt were SA, 39 Pt were FS and 4 Pt were both). The relative risk ofSA was ten times larger for those with FS. Psychiatric Medication: Antipsychotics: 15Pt (8%), Antidepressants: 23 Pt (12%) and Benzodiazepines 45 Pt(24%), No treatment 101 Pt (55%). Population Characteristics: Sex: F:144 Pt . M: 40 Pt. Age: 56y (r = 26-88). Tumor Dx: Breast (65 Pt ) - Gastrointestinal (24 Pt) - Urological (21 Pt ) - Lung (21 Pt ) -Gynecological (19 Pt) - Hematological (11 Pt) -Head &Neck (8 Pt) - Endocrine (7 Pt) - Other (8 Pt). Stages: Early (0-I-II-III): 130 Pt, Advanced: 54 Pt. Ob-Gyn history:25 Pt (17%) nulliparous, 18 Pt (12%) with one child, 77 Pt (53%) with 2 or 3 children and 24 Pt (17%) with more than 3 children; 62 Pt (43%) had previous abortions. Average severe comorbidities (respiratory and psychiatric) was 3 per Pt (r = 0-18). Toxic habits: Smoking: 120 Pt (65%), Alcohol: 37 Pt (20%) and Illicit Drugs: 4 Pt (2%). Follow-up: 19 months (r = 0-70). No Pt had any SA, or commited suicide, during the follow-up.Living patients:177 (96%). Conclusions: 1) In our vast cohort, 184 Pt (1.2%) were identified as highly vulnerable psychiatric Pt due to SAFS. 2) Given the high psychological risk and stressful cancer diagnosis, 83 Pt (45%) were prescribed psychiatric drugs. 3) Follow-up of SAFS Pt by a multidisciplinary team is requiredfor adequate Pt and family support.

Prevalence of and Risk Factors for Suicide Attempts Among Patients With Severe Psychiatric Disorders in Eastern Morocco

Crisis ◽  
2021 ◽  
Author(s):  
Mohammed Barrimi ◽  
Khalid Serraj ◽  
Ismail Rammouz ◽  
Rachid Alouane ◽  
Najoua Messaoudi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Family History ◽  
Suicide Attempt ◽  
Psychiatric Disorders ◽  
Suicide Attempts ◽  
Personal History ◽  
University Hospital ◽  
Number Of Patients ◽  
History Of ◽  
Risk Factors For Suicide

Abstract. Background: Suicide attempts are common in patients with severe psychiatric disorders; however, they are rarely studied in this population. Aims: To investigate the prevalence and risk factors associated with suicide attempts among patients with severe psychiatric disorders. Method: This is a cross-sectional study of patients admitted to the Mohammed VI University Hospital of Psychiatry in Oujda, Morocco. Results: A total of 250 patients with a psychiatric disorder were recruited in this study. Among these, 78 cases (31.2%) had a personal history of suicide attempts. A personal history of suicide attempt was significantly higher among women compared to men (45.5% vs. 27.2%, p = .0099). The most common method of suicide attempts was jumping from heights (31%). Patients with a personal history of suicide attempts had a significantly higher prevalence of alcohol consumption ( p = .0063), family history of psychiatric disorders ( p = .002), family history of suicide attempt ( p = .00004), and family history of suicide ( p = .018) compared to those who had never made suicide attempts. Limitations: As suicidal behavior is highly stigmatized in Morocco, the number of patients who have made a suicide attempt may be underestimated. Conclusion: Our findings justify the need to provide specialized support to psychiatric patients with risk factors for suicide attempts.

Suicide Attempts and Family History of Suicide in Three Psychiatric Populations

2005 ◽  
Vol 35 (6) ◽  
pp. 702-713 ◽  
Author(s):  
Fabien Trémeau ◽  
Luc Staner ◽  
Fabrice Duval ◽  
Humberto Corrêa ◽  
Marc-Antoine Crocq ◽  
...  
Keyword(s):  
Family History ◽  
Suicide Attempts ◽  
History Of

scholarly journals Association of family history of schizophrenia and clinical outcomes in individuals with eating disorders

2021 ◽  
pp. 1-8
Author(s):  
Ruyue Zhang ◽  
Ralf Kuja-Halkola ◽  
Andreas Birgegård ◽  
Henrik Larsson ◽  
Paul Lichtenstein ◽  
...  
Keyword(s):  
Mental Health ◽  
Eating Disorders ◽  
Family History ◽  
Anxiety Disorders ◽  
Clinical Outcomes ◽  
Suicide Attempts ◽  
Compulsive Disorder ◽  
First Degree Relatives ◽  
Health Burden ◽  
History Of

Abstract Background Familial co-aggregation studies of eating disorders (EDs) and schizophrenia reveal shared genetic and environment factors, yet their etiological and clinical relationship remains unclear. We evaluate the influence of schizophrenia family history on clinical outcomes of EDs. Methods We conducted a cohort evaluation of the association between family history of schizophrenia and ED clinical features, psychiatric comorbidities, and somatic and mental health burden in individuals born in Sweden 1977–2003 with anorexia nervosa (AN) or other EDs (OED: bulimia nervosa, binge-eating disorder, and ED not otherwise specified). Results Of 12 424 individuals with AN and 20 716 individuals with OED, 599 (4.8%) and 1118 (5.4%), respectively, had a family history of schizophrenia (in up to third-degree relatives). Among individuals with AN, schizophrenia in first-degree relatives was significantly associated with increased comorbid attention-deficit/hyperactivity disorder (ADHD) [HR(95% CI) 2.26 (1.27–3.99)], substance abuse disorder (SUD) [HR (95% CI) 1.93 (1.25–2.98)], and anxiety disorders [HR (95% CI) 1.47 (1.08–2.01)], but higher lowest illness-associated body mass index (BMI) [1.14 kg/m2, 95% CI (0.19–2.10)]. Schizophrenia in any relative (up to third-degree) in AN was significantly associated with higher somatic and mental health burden, but lower ED psychopathology scores [−0.29, 95% CI (−0.54 to −0.04)]. Schizophrenia in first-degree relatives in individuals with OED was significantly associated with increased comorbid ADHD, obsessive-compulsive disorder, SUD, anxiety disorders, somatic and mental health burden, and suicide attempts. Conclusions We observed different patterns of ED-related outcomes, psychiatric comorbidity, and illness burden in individuals with EDs with and without family histories of schizophrenia and provide new insights into the diverse manifestations of EDs.

scholarly journals Clinical correlates of first episode schizophrenia-a comparative study

2018 ◽  
Vol 6 (2) ◽  
pp. 551
Author(s):  
Kathir M. ◽  
Pugazhendhi K. ◽  
Ravishankar J.
Keyword(s):  
Family History ◽  
Negative Symptoms ◽  
Suicide Attempts ◽  
Social Withdrawal ◽  
First Episode ◽  
Positive Symptoms ◽  
Major Mental Disorder ◽  
History Of ◽  
Drug Naïve ◽  
First Episode Schizophrenia

Background: Schizophrenia is a major mental disorder which has to be assessed early and managed actively even though long term functional outcome remains relatively poor. The aim of the study is to analyze negative symptoms, suicidal risk and substance use in first episode schizophrenics in comparison with multi-episode schizophrenics.Methods: 30 patients with drug naive first episode schizophrenia and 30 patients with multi episode schizophrenia, who attended the outpatient department of Psychiatry, Government Stanley Medical College, Chennai, Tamilnadu, India were studied to compare predisposing factors and spectrum of symptoms for Schizophrenia for a period of one year (January 2010-December 2010). Psychiatric questionnaire by Michael C. Hilton, DAST by Harvey A. Skinner, AUDIT by WHO, Suicide risk scale by National Health and Medical Research Council, PANSS by SR Kay were used to assess patients.Results: Unemployment and family history of suicide attempts were observed more in drug naive first episode schizophrenics. 90% of these patients had completed their primary education while 47% of multi-episode schizophrenics were illiterates. Positive symptoms (delusions, hallucinatory behaviour and suspiciousness) and negative symptoms (blunted affect, emotional withdrawal and social withdrawal) were observed more in first episode schizophrenics while PANSS, DAST, AUDIT scores did not find any differences between both the groups.Conclusions: In our study, the first episode schizophrenia patients were more educated, more unemployed and had more family history of suicide, elevated sub score of positive symptoms as measured by PANSS. Relative assessment of violence and serious behavior problems that are related to positive symptoms must be done and managed with anti psychotics.

Bullying and Suicide Attempts Among Adolescents Kept in Custody

Crisis ◽  
2008 ◽  
Vol 29 (4) ◽  
pp. 216-218 ◽  
Author(s):  
Stavros P. Kiriakidis
Keyword(s):  
Family History ◽  
General Population ◽  
Suicide Attempts ◽  
Violent Offender ◽  
Institutional Characteristics ◽  
Young Offenders ◽  
Increased Risk ◽  
The Family ◽  
History Of ◽  
Being Bullied

This contribution explores the associations between suicide attempts; bullying; and the familial, educational, legal, and institutional characteristics of young offenders in custody. The sample was 152 randomly selected male young offenders aged 16–21 years (M = 18.9, SD = 1.3) years from the largest young offenders’ institution in Scotland, who completed structured personal interviews. Rates of reported suicide attempts were significantly higher in the population of young offenders than reported rates from general population samples. Being in residential care, the presence of a social worker for the family, family history of alcohol abuse, family history of suicide attempts, the experience of being bullied in custody, contact with a psychologist in the community, and being a violent offender were significantly related to increased risk of suicide attempts in custody. Compared to those who were not bullied, offenders who were bullied in custody were 9.22 times more likely to attempt suicide. The implications these findings for reducing bullying in penal settings are discussed.

scholarly journals An Analysis of Five TrkB Gene Polymorphisms in Schizophrenia and the Interaction of Its Haplotype with rs6265 BDNF Gene Polymorphism

2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Renata Suchanek-Raif ◽  
Paweł Raif ◽  
Małgorzata Kowalczyk ◽  
Monika Paul-Samojedny ◽  
Aleksandra Zielińska ◽  
...  
Keyword(s):  
Family History ◽  
Case Control Study ◽  
Suicide Attempts ◽  
Five Factor Model ◽  
Case Control ◽  
Nucleotide Polymorphisms ◽  
Increased Risk ◽  
Polymorphic Genotype ◽  
History Of ◽  
Control Study

Aim. The BDNF dysfunction in the schizophrenia has been soundly documented. The TrkB gene is a high-affinity receptor of the BDNF that is changed in schizophrenia and mood disorders. The study had two aims: first, to identify whether the five nucleotide polymorphisms (SNPs) in TrkB gene are associated with a diagnosis of schizophrenia; and the latter, if any association exists between the TrkB SNPs and psychopathology, suicide attempts, and family history of schizophrenia in a Caucasian population. Methods. Case-control study (401 patients and 657 healthy controls) was used to examine a predisposition for schizophrenia. The tests for psychopathology, suicide attempts, and family history of schizophrenia were conducted only in patient group. The severity of the schizophrenia was measured using the five-factor model of the PANSS. In addition, the haplotype analysis for both the separate for SNPs of TrkB gene and in combination with the rs6265 SNP BDNF gene was conducted. Results. Our case-control study revealed that the genetic variants of rs10868235 (T/T polymorphic genotype) and rs1387923 (G/G polymorphic genotype) of the TrkB gene were associated with a higher risk of developing schizophrenia in men. However, the A/A wild genotype of rs1387923 was connected with a lower risk for both the development of and the family manifestation of schizophrenia in men. The G polymorphic allele of rs1565445 was associated with an increased risk of suicide in schizophrenia. The tested SNPs of the TrkB gene did not modulate the psychopathology of schizophrenia. The haplotype that was built with five SNPs in the TrkB gene was protective for men, but after joining the rs6265 SNP of the BDNF gene, a haplotype that was protective for women was created.

Searching for Variables Associated with Familial Suicide Attempts Using Data Mining Techniques

2009 ◽  
Vol 24 (S1) ◽  
pp. 1-1 ◽  
Author(s):  
D. Saiz-Gonzalez ◽  
E. Baca-García ◽  
M. Perez-Rodriguez ◽  
I. Basurte Villamor ◽  
J. Saiz-Ruiz ◽  
...  
Keyword(s):  
Data Mining ◽  
Family History ◽  
Attempted Suicide ◽  
Suicide Attempts ◽  
Forward Selection ◽  
Data Mining Techniques ◽  
Completed Suicide ◽  
Familial Form ◽  
History Of ◽  
Using Data

Introduction:Adoption, twin and family studies suggest that suicide behavior is familial and heritable. Both completed and attempted suicide appear to be transmitted in a familial form. Genetics and environment influences had been detected in various studies. But suicidal behavior suggests to be inherited independently from the mental disorders usually associated with it. While traditional statistics emphasizes inference and estimations, data mining emphasizes the fulfillment of a task such as classification, estimation, or knowledge discovery.Objectives:The goal of this study was to determine in a large sample of suicide attempts which variables are associated with family history of attempted suicide.Methods:In an emergency room, 539 adult suicide attempters were recruited. The two dichotomous dependent variables were family history of suicide attempt (10%) and of completed suicide (4%). Independent variables were 101 clinical variables explored with two data mining techniques: Random Forest and Forward Selection.Results:A model for family history of completed suicide could not be developed. A classificatory model for family history of attempted suicide included the use of alcohol in the intent and family history of completed suicide, provide a sensitivity of 78.4%, a specificity of 98.7% and accuracy of 96.6%.Conclusions:A classificatory model for family history of completed suicide could not be developed using data mining techniques. But it suggested that the use of alcohol in the intent and family history of completed suicide may be associated with familial attempted suicide.

scholarly journals Suicide in Older Adult Men Is Not Related to a Personal History of Participation in Football

2021 ◽  
Vol 12 ◽  
Author(s):  
Grant L. Iverson ◽  
Amy Deep-Soboslay ◽  
Thomas M. Hyde ◽  
Joel E. Kleinman ◽  
Brittany Erskine ◽  
...  
Keyword(s):  
Mental Health ◽  
High School ◽  
Family History ◽  
Suicide Ideation ◽  
Suicide Attempts ◽  
Personal History ◽  
Medical Examiner ◽  
High School Football ◽  
Manner Of Death ◽  
History Of

Introduction: It is reasonable to estimate that tens of millions of men in the United States played high school football. There is societal concern that participation in football confers risk for later-in-life mental health problems. The purpose of this study is to examine whether there is an association between a personal history of playing high school football and death by suicide.Methods: The subjects were obtained from the Lieber Institute for Brain Development (LIBD) brain donation program in collaboration with the Office of the Medical Examiner at Western Michigan University Homer Stryker MD School of Medicine. Donor history was documented via medical records, mental health records, and telephone interviews with the next-of-kin.Results: The sample included 198 men aged 50 or older (median = 65.0 years, interquartile range = 57–75). There were 34.8% who participated in contact sports during high school (including football), and 29.8% participated in high school football. Approximately one-third of the sample had suicide as their manner of death (34.8%). There was no statistically significant difference in the proportions of suicide as a manner of death among those men with a personal history of playing football compared to men who did not play football or who did not play sports (p = 0.070, Odds Ratio, OR = 0.537). Those who played football were significantly less likely to have a lifetime history of a suicide attempt (p = 0.012, OR = 0.352). Men with mood disorders (p < 0.001, OR = 10.712), substance use disorders (p < 0.020, OR = 2.075), and those with a history of suicide ideation (p < 0.001, OR = 8.038) or attempts (p < 0.001, OR = 40.634) were more likely to have suicide as a manner of death. Moreover, those men with a family history of suicide were more likely to have prior suicide attempts (p = 0.031, OR = 2.153) and to have completed suicide (p = 0.001, OR = 2.927).Discussion: Suicide was related to well-established risk factors such as a personal history of a mood disorder, substance abuse disorder, prior suicide ideation, suicide attempts, and a family history of suicide attempts. This study adds to a steadily growing body of evidence suggesting that playing high school football is not associated with increased risk for suicidality or suicide during adulthood.

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