15:30 CHILDHOOD AND ADOLESCENCE SYMPTOMS PREDICTING FIRST EPISODE PSYCHOSIS IN THE GENERAL POPULATION BASED NORTHERN FINLAND 1986 BIRTH COHORT

2012 ◽  
Vol 136 ◽  
pp. S86
Author(s):  
Pirjo H. Mäki ◽  
Jouko Miettunen ◽  
Irma Moilanen ◽  
Marika Kaakinen ◽  
Anja Taanila ◽  
...  
Keyword(s):  
General Population ◽  
Birth Cohort ◽  
Population Based ◽  
First Episode Psychosis ◽  
First Episode ◽  
Childhood And Adolescence ◽  
Episode Psychosis

Difficulty in making contact with others and social withdrawal as early signs of psychosis in adolescents – the Northern Finland Birth Cohort 1986

2014 ◽  
Vol 29 (6) ◽  
pp. 345-351 ◽  
Author(s):  
P. Mäki ◽  
S. Koskela ◽  
G.K. Murray ◽  
T. Nordström ◽  
J. Miettunen ◽  
...  
Keyword(s):  
General Population ◽  
Mental Disorder ◽  
Birth Cohort ◽  
Psychotic Disorders ◽  
Social Withdrawal ◽  
Population Based ◽  
Clinical Samples ◽  
First Episode ◽  
Control Group ◽  
Episode Psychosis

AbstractAimSocial withdrawal is among the first signs of the prodromal state of psychosis seen in clinical samples. The aim of this prospective study was to find out whether difficulty in making contact with others and social withdrawal precede first episode psychosis in the young general population.MethodsThe members of the Northern Finland Birth Cohort 1986 (n = 6274) completed the PROD-screen questionnaire in 2001–2002. The Finnish Hospital Discharge Register was used to detect both new psychotic and non-psychotic disorders requiring hospitalisation during 2003–2008.ResultsTwenty-three subjects developed psychosis and 89 developed a non-psychotic mental disorder requiring hospitalisation during the follow-up. Of those who developed psychosis, 35% had reported difficulty or uncertainty in making contact with others and 30% social withdrawal in adolescence. In hospitalised non-psychotic disorder, the corresponding precentages were 10 and 13% and in the control group without hospital-treated mental disorder 9 and 11%. The differences between psychotic and non-psychotic hospitalised subjects (P < 0.01) as well as controls (P < 0.001) were statistically significant regarding difficulty or uncertainty in making contact with others.ConclusionsIn this general population-based sample self-reported difficulty or uncertainty in making contact with others in adolescence preceded psychosis specifically compared to hospitalised non-psychotic mental disorders and controls.

scholarly journals Substance use in a population-based clinic sample of people with first-episode psychosis

2007 ◽  
Vol 190 (6) ◽  
pp. 515-520 ◽  
Author(s):  
Jennifer H. Barnett ◽  
Ursula Werners ◽  
Sandra M. Secher ◽  
Katherine E. Hill ◽  
Rossa Brazil ◽  
...  
Keyword(s):  
Substance Use ◽  
General Population ◽  
Population Based ◽  
First Episode Psychosis ◽  
Psychotic Symptoms ◽  
First Episode ◽  
Psychotic Episode ◽  
Intervention Service ◽  
Episode Psychosis ◽  
British Crime Survey

BackgroundSubstance use is implicated in the cause and course of psychosis.AimsTo characterise substance and alcohol use in an epidemiologically representative treatment sample of people experiencing a first psychotic episode in south Cambridgeshire.MethodCurrent and lifetime substance use was recorded for 123 consecutive referrals to a specialist early intervention service. Substance use was compared with general population prevalence estimates from the British Crime Survey.ResultsSubstance use among people with first-episode psychosis was twice that of the general population and was more common in men than women. Cannabis abuse was reported in 51% of patients (n=62) and alcohol abuse in 43% (n=53). More than half (n=68, 55%) had used Class A drugs, and 38% (n=43) reported polysubstance abuse. Age at first use of cannabis, cocaine, ecstasy and amphetamine was significantly associated with age at first psychotic symptom.ConclusionsSubstance misuse is present in the majority of people with first-episode psychosis and has major implications for management. The association between age at first substance use and first psychotic symptoms has public health implications.

Estimating the incidence of first-episode psychosis using population-based health administrative data to inform early psychosis intervention services

2018 ◽  
Vol 49 (12) ◽  
pp. 2091-2099 ◽  
Author(s):  
Kelly K. Anderson ◽  
Ross Norman ◽  
Arlene G. MacDougall ◽  
Jordan Edwards ◽  
Lena Palaniyappan ◽  
...  
Keyword(s):  
Psychotic Disorder ◽  
Administrative Data ◽  
Catchment Area ◽  
Population Based ◽  
First Episode Psychosis ◽  
Case Definition ◽  
First Episode ◽  
Affective Psychosis ◽  
Health Administrative Data ◽  
Episode Psychosis

AbstractBackgroundDiscrepancies between population-based estimates of the incidence of psychotic disorder and the treated incidence reported by early psychosis intervention (EPI) programs suggest additional cases may be receiving services elsewhere in the health system. Our objective was to estimate the incidence of non-affective psychotic disorder in the catchment area of an EPI program, and compare this to EPI-treated incidence estimates.MethodsWe constructed a retrospective cohort (1997–2015) of incident cases of non-affective psychosis aged 16–50 years in an EPI program catchment using population-based linked health administrative data. Cases were identified by either one hospitalization or two outpatient physician billings within a 12-month period with a diagnosis of non-affective psychosis. We estimated the cumulative incidence and EPI-treated incidence of non-affective psychosis using denominator data from the census. We also estimated the incidence of first-episode psychosis (people who would meet the case definition for an EPI program) using a novel approach.ResultsOur case definition identified 3245 cases of incident non-affective psychosis over the 17-year period. We estimate that the incidence of first-episode non-affective psychosis in the program catchment area is 33.3 per 100 000 per year (95% CI 31.4–35.1), which is more than twice as high as the EPI-treated incidence of 18.8 per 100 000 per year (95% CI 17.4–20.3).ConclusionsCase ascertainment strategies limited to specialized psychiatric services may substantially underestimate the incidence of non-affective psychotic disorders, relative to population-based estimates. Accurate information on the epidemiology of first-episode psychosis will enable us to more effectively resource EPI services and evaluate their coverage.

Cognitive deficits in first-episode psychosis: A population-based study in São Paulo, Brazil

2007 ◽  
Vol 90 (1-3) ◽  
pp. 338-343 ◽  
Author(s):  
A AYRES ◽  
G BUSATTO ◽  
P MENEZES ◽  
M SCHAUFELBERGER ◽  
L COUTINHO ◽  
...  
Keyword(s):  
Cognitive Deficits ◽  
Population Based ◽  
First Episode Psychosis ◽  
Sao Paulo ◽  
First Episode ◽  
São Paulo ◽  
Population Based Study ◽  
Episode Psychosis

scholarly journals Neurological abnormalities and cognitive ability in first-episode psychosis

2008 ◽  
Vol 193 (3) ◽  
pp. 197-202 ◽  
Author(s):  
Paola Dazzan ◽  
Tuhina Lloyd ◽  
Kevin D. Morgan ◽  
Jolanta Zanelli ◽  
Craig Morgan ◽  
...  
Keyword(s):  
General Population ◽  
Cognitive Ability ◽  
Motor Coordination ◽  
First Episode Psychosis ◽  
First Episode ◽  
Control Group ◽  
General Cognitive Ability ◽  
Affective Psychosis ◽  
Neurological Soft Signs ◽  
Episode Psychosis

BackgroundIt remains unclear if the excess of neurological soft signs, or of certain types of neurological soft signs, is common to all psychoses, and whether this excess is simply an epiphenomenon of the lower general cognitive ability present in psychosis.AimsTo investigate whether an excess of neurological soft signs is independent of diagnosis (schizophrenia v. affective psychosis) and cognitive ability (IQ).MethodEvaluation of types of neurological soft signs in a prospective cohort of all individuals presenting with psychoses over 2 years (n=310), and in a control group from the general population (n=239).ResultsPrimary (P<0.001), motor coordination (P<0.001), and motor sequencing (P<0.001) sign scores were significantly higher in people with any psychosis than in the control group. However, only primary and motor coordination scores remained higher when individuals with psychosis and controls were matched for premorbid and current IQ.ConclusionsHigher rates of primary and motor coordination signs are not associated with lower cognitive ability, and are specific to the presence of psychosis.

CHILDHOOD AND ADOLESCENCE PREDICTORS OF PSYCHOSIS IN THE GENERAL POPULATION -BASED NORTHERN FINLAND 1986 BIRTH COHORT

2010 ◽  
Vol 117 (2-3) ◽  
pp. 172-173
Author(s):  
Pirjo H. Mäki ◽  
Jouko Miettunen ◽  
Marika Kaakinen ◽  
Irma K. Moilanen ◽  
Anja Taanila ◽  
...  
Keyword(s):  
General Population ◽  
Birth Cohort ◽  
Population Based ◽  
Childhood And Adolescence
Sign in / Sign up

Export Citation Format

Share Document