P01-208-Prevalence of hypomania in patients with diagnosis of affective disorder

2011 ◽  
Vol 26 (S2) ◽  
pp. 209-209
Author(s):  
I. Garcia Del Castillo ◽  
L. Fernandez Mayo ◽  
R. Carmona Camacho ◽  
M.J. Martin Calvo ◽  
E. Serrano Drozdowskyj ◽  
...  
Keyword(s):  
High Sensitivity ◽  
Unipolar Depression ◽  
Epidemiological Studies ◽  
Self Report ◽  
Future Research ◽  
Control Group ◽  
Bipolar Ii Disorder ◽  
Bipolar Ii ◽  
Dsm Iv ◽  
The Difference

IntroductionRecent epidemiological studies suggest that the prevalence of bipolar disorder might be misdiagnosed initially as unipolar depression due to the difficulty to detect episodes of hypomania. The Hypomania Checklist (HCL-32), validated in Spanish, is a self-report questionnaire with 32 hypomania items designed to screen for hypomanic episodes.ObjectivesTo examine the prevalence of hypomania in patients with unipolar depression. Corroborate the efficacy of the HCL-32 to detect symptoms of hypomania.MethodsThe presence of hypomanic symptoms was assessed by the HCL-32 in a sample of 128 subjects diagnosed with bipolar I disorder (n = 30), bipolar II disorder (n = 1), unipolar depression (n = 57), and anxiety disorder (n = 15) according to DSM-IV-TR criteria. A control group of healthy subjects was selected (n = 25).ResultsThe discriminative capacity was analyzed by the ROC curve. The AUC was 0.65 which did not indicate a good capacity. The sensitivity (S), specificity (E) and prevalence (P) of hypomania in unipolar patients for the following cut-off points were :14: S = 81.6%,95%CI(69.8, 93.5); E = 30.1%,95%CI(19.7,40.6); P = 74.1%; 15: S = 77.6%,95%CI(64.9,90.3); E = 37.4%,95%CI(26.3,48.4); P = 67.2%; 16: S = 59.2%,95%CI(44.4,73.9); E = 55.4%,95%CI(44.1,74.0); P = 51.7%; 17: S = 55.1%,95%CI(40.2,70.1); E = 57.8%,95%CI(46.6,69.1); P = 48.3%.ConclusionsThe HCL-32 has a high sensitivity but a low specificity as screening instrument. This might explain the high proportion of hypomania found in this study. The difference with previous studies is that our sample was heterogeneous, unstable and serious. This suggests that the HCL-32 is not valid for any psychiatric sample. Future research should develop more specific instruments with better external validity.

Migraine headache and bipolar disorder comorbidity: A systematic review of the literature and clinical implications

2016 ◽  
Vol 11 (1) ◽  
pp. 136-145 ◽  
Author(s):  
Raphael J. Leo ◽  
Joshna Singh
Keyword(s):  
Systematic Review ◽  
Bipolar Disorder ◽  
Migraine Headache ◽  
Unipolar Depression ◽  
Epidemiological Studies ◽  
Prevalence Rates ◽  
Review Of The Literature ◽  
Weighted Mean ◽  
Bipolar Ii Disorder ◽  
Bipolar Ii

AbstractBackground and aimsPsychiatric disorders, e.g., depression, are often comorbid with, and can complicate the treatment of, patients with migraine headache. Although empirical work has increasingly focused on the association between migraine and bipolar disorder, this topic has received little attention in the pain literature. Bipolar disorder is a chronic and recurrent mood disorder characterized by cyclic occurrence of elevated (i.e., manic or hypomanic) and depressed mood states. Bipolar I disorder is diagnosed when patients present with at least one abnormally and persistently elevated manic episode; bipolar II disorder is characterized by the presence of hypomanic episodes. Bipolar disorder warrants attention as depressive phases of the disorder can prevail and are often misconstrued by the unwary clinician as unipolar depression. However, treatment for bipolar disorder is distinct from that of unipolar depression and use of antidepressants, which are often invoked in migraine prophylaxis as well as the treatment of depression, may precipitate significant mood changes among bipolar disorder patients. A systematic review of the literature addressing the co-occurrence of bipolar disorder and migraine was conducted. The treatment of dually affected patients is also discussed.MethodsIn order to review the literature to date on migraine and bipolar disorder co-occurrence, a comprehensive search of MEDLINE, EMBASE, PubMed, PsycINFO, Web of Science, and CINAHL for clinic-based and epidemiological studies was conducted using terms related to migraine and bipolar disorder. Studies were selected for review if they included subjects meeting validated diagnostic criteria for bipolar disorder as well as migraine headache and if a quantitative description of prevalence rates of comorbid bipolar disorder and migraine were reported. Weighted means of the prevalence rates were calculated to compare with general epidemiological prevalence trends for migraine and bipolar disorder, respectively.ResultsEleven studies met inclusion criteria. Although findings were constrained by methodological limitations and several low quality studies, clinic- and epidemiological cross-sectional investigations demonstrated a high rate of comorbidity between bipolar disorder and migraine. The weighted mean prevalence rate for migraine headache among bipolar disorder patients was 30.7%; for bipolar disorder among migraineurs, the weighted mean prevalence rates were 9% and 5.9% in clinic-based and epidemiological studies, respectively. The association between bipolar disorder and migraine was most notable among women and patients with the bipolar II disorder subtype.ConclusionsHigh rates of comorbidity exist between migraine and bipolar disorder, exceeding estimated prevalence rates for those conditions in the general population. Comorbidity may portend a more serious clinical course for dually afflicted individuals.ImplicationsClinicians need to structure treatment approaches to address concurrent migraine and bipolar disorder in dually afflicted individuals. Although further evidence-based investigation is warranted to inform optimal treatment approaches for both conditions concurrently, anticonvulsants (e.g., valproate, lamotrigine and topiramate); atypical antipsychotics (e.g., olanzapine or quetiapine); and calcium channel blockers (e.g., verapamil) may be considered.

How low do we go? Is duration of a ‘high’ integral to the definition of bipolar disorder?

2007 ◽  
Vol 19 (1) ◽  
pp. 38-44 ◽  
Author(s):  
Lucy Tully ◽  
Gordon Parker
Keyword(s):  
Bipolar Disorder ◽  
Clinical Features ◽  
Symptom Severity ◽  
Self Report ◽  
Web Based ◽  
Bipolar Ii Disorder ◽  
Bipolar Ii ◽  
Considerable Debate ◽  
Dsm Iv ◽  
Definition Of

Objective:There has been considerable debate about the diagnostic rules for bipolar II disorder, particularly the 4-day duration criteria for hypomanic episodes. This study examined whether highs lasting minutes or hours differed from longer highs in terms of clinical features and symptom severity. It also examined whether duration of highs predicted bipolar disorder being diagnosed.Method:A total of 518 subjects with significant episodes of depression and ‘highs’ completed a web-based self-report questionnaire. Those who reported their longest highs lasting minutes or hours were compared with those who reported longer durations of highs on a range of clinical variables and measures of symptom severity.Results:Subjects whose highs lasted minutes or hours reported clinical features and severity of symptoms similar to those whose highs lasted 3–7 days. However, the odds of being diagnosed with bipolar disorder for those with highs lasting 3–7 days were almost three times higher than for those whose highs lasted minutes or hours.Conclusion:The 4-day DSM-IV minimum-duration criteria for hypomania may lead to failure to diagnose subjects with brief highs who have true bipolar disorder and thus should be reconsidered.

The Impact of Domestic Violence on Women’s Self-Attitude in Kazakhstan

2020 ◽  
pp. 77-83
Author(s):  
Zhanna Kalmatayeva
Keyword(s):  
Domestic Violence ◽  
Quantitative Research ◽  
Self Esteem ◽  
Self Report ◽  
Control Group ◽  
Personality Research ◽  
Attitude Test ◽  
The Difference ◽  
Student’S T ◽  
The Impact

The purpose of the article was to study the problems of domestic violence of women and its consequences in Kazakhstan. The analysis of the results of the study of self-attitude and self-esteem of women subjected to domestic violence. Revealed there is a correlation between the level of self-attitude of domestic violence victims and the non-differentiated I-concept. 140 women participated in the present study, 70 women are control group which not subjected to domestic violence and 70 women of them who have currently reported domestic violence in the Crisis Center "Umit" in Nur-Sultan in the period from November 2017 to October 2019. Quantitative research method was used in terms of survey model by implementing a psychological test “The self-attitude test questionnaire (SA)” that assesses self-relation, differentiated by self-esteem, self-sympathy, self-interest, and expectations of self-reliance of participants. Also, during the study was used personal questionnaire “Who am I?” a variant of non-standardized self-report, approaching the projective methods of personality research. Descriptive statistics were used to analyze the answers in terms of their levels of the participants’ self-esteem and self-relation and further, since it was revealed according to the results reflect the difference in the two groups by the values obtained from these scales, the Student's t-test for independent groups was used [2] was used to reveal whether there is any correlation between the components of the scale. The obtained results can be used to interventions and training of family for counselors in order to promote women's self-esteem and self-relation.

scholarly journals Hypomanic Symptoms in Female Undergraduate Students Diagnosed with Unipolar Depression Based on Scores on the Hypomania Checklist

2009 ◽  
Vol 5 (1) ◽  
pp. 22-25 ◽  
Author(s):  
Thomas Richardson ◽  
Hugh Garavan
Keyword(s):  
Bipolar Disorder ◽  
Undergraduate Students ◽  
Unipolar Depression ◽  
Female Undergraduate ◽  
Bipolar Ii Disorder ◽  
Bipolar Ii

Background: A number of studies have documented high levels of hypomanic symptoms in those diagnosed with depression, suggesting a potential misdiagnosis of bipolar disorder as unipolar depression. Research suggests that undergraduate students have high levels of depression, but whether such misdiagnosis occurs in this population has not been examined. The aim of this study was therefore to examine levels of hypomania in undergraduate students reporting diagnosed depression. Methods: An international sample of undergraduate students completed the 32-item Hypomania Checklist (HCL-32). A cohort was analysed for this study, consisting of female undergraduate students reporting a formal diagnosis of depression (n=28). Results: Participants scored high on the HCL-32, with a mean total score of 19.9 (SD=5.4) out of 32. Overall, 85.7% (n=24) scored equal to or above the original cut off point of 14 suggested for bipolar II disorder. Conclusions: Two possible conclusions are suggested by this study. Firstly, there are high levels of hypomanic symptoms in undergraduate students diagnosed with depression, suggesting that a formal diagnosis of bipolar disorder should be pursued in those with high scores. Alternatively, the cut-off points previously suggested for the HCL-32 may not be accurate for use with undergraduate students.

Serum uric acid levels in optic neuritis

2004 ◽  
Vol 10 (3) ◽  
pp. 278-280 ◽  
Author(s):  
C M Knapp ◽  
C S Constantinescu ◽  
J HY Tan ◽  
R McLean ◽  
G R Cherryman ◽  
...  
Keyword(s):  
Uric Acid ◽  
Optic Neuritis ◽  
Serum Uric Acid ◽  
Future Research ◽  
Control Group ◽  
Female Group ◽  
Small Male ◽  
Recent Onset ◽  
Male Cohort ◽  
The Difference

Uric acid, an antioxidant, is reduced in multiple sclerosis (MS). Patients with gout have a reduced incidence of MS. O ptic neuritis (O N), often the first manifestation of MS, is not known to be associated with reduced uric acid. Patients with recent onset of O N were investigated to determine whether uric acid levels were reduced at presentatio n. Twenty-o ne patients with O N were included, 17 females and 4 males. The mean (SD) serum uric acid in the O N female group was 184.4 (±55.1) mmol/L (range, 116- 309 mmol/L), whilst in the control group it was 235.2 (±50.2) mmol/L (range, 172- 381 mmol/L). The difference was statistically significant (x2 = 8.93, P = 0.003). In the small male cohort, mean (SD) serum uric acid was 305 (±52.1) mmol/L, whilst in the control group it was 328 (±80.4) mmol/L. These differences were not statistically significant. Reduced antioxidant reserve is possibly an early patho genic mechanism in inflammatory demyelination, and raises the possibility that low uric acid levels could be an indicator of disease activity. Since optic neuropathies of other causes were not investigated, future research needs to determine whether low uric acid represents a unique feature of optic neuritis or is seen in other optic neuropathies.

Effect of Mind Mapping on Creative Thinking of Children in Scratch Visual Programming Education

2021 ◽  
pp. 073563312110533
Author(s):  
Yu-Sheng Su ◽  
Mingming Shao ◽  
Li Zhao
Keyword(s):  
Creative Thinking ◽  
Thinking Skills ◽  
Visual Programming ◽  
Mapping Method ◽  
Self Report ◽  
Primary School Children ◽  
Control Group ◽  
Mind Mapping ◽  
Digital World ◽  
The Difference

Scratch, a kind of visual programming software, has been widely used in instruction for primary school children. Scratch constructs a digital world for children to design, develop, and create coursework in which their creative thinking is fostered. Different instructional methods have been designed and implemented to stimulate children’s creative thinking skills through their coursework. This study investigated whether scaffolding construction with mind mapping promoted children’s creative thinking in a Scratch course. Two groups of 84 fifth-grade pupils participated in the study. The experimental group of 44 students adopted the scaffolding construction with mind mapping in the Scratch course, while the control group of 40 students did not use the mind mapping method. The Torrance Tests of Creative Thinking-Figural (TTCT-F) and Torrance Creative Personality Self-Report Scale were used three times over the 16-week learning period. The results show that learning in the Scratch course promoted the children’s creative thinking. The difference between the two groups indicates that mind mapping was beneficial to improve the children’s creative thinking.

The Learning Assessment Centre and Organisational Transformation

2005 ◽  
Vol 35 (4) ◽  
pp. 810-830
Author(s):  
Jonathan Cook ◽  
Michael Muller ◽  
Ian Cutler
Keyword(s):  
Peer Assessment ◽  
Substantial Improvement ◽  
Self Report ◽  
Learning Assessment ◽  
Control Group ◽  
Before And After ◽  
Post Test ◽  
Assessment Centre ◽  
The Difference ◽  
Experimental Group

The learning assessment centre helps managers define learning objectives based on feedback in a group of peers. This study tested the hypothesis that the centre empowers managers to cope with change. Statistical methodology for a pre-test, post-test design using ordinal (Likert) data is also reviewed. Middle managers from a bank undergoing major reorganisation were divided into two matched groups. The experimental group spent three days in a learning assessment centre designed to give them self-insight and an understanding of the bank's requirements during the transformation. The control group received no treatment. Both groups were measured before and after the centre on a self-report measure and completed a peer assessment questionnaire completed by subordinates. Fifty-eight managers completed both pre-test and post-test measures. Whilst the subordinates of the control group reported a drop in their managers' empowerment, the subordinates of the experimental group reported a substantial improvement in their managers' empowerment. The difference between the groups was significant for five of the six areas measured. The difference between the self-reported performance of the two groups of managers was significant for only one area. These findings suggest that the learning centre could provide a solution to companies faced with the potentially destructive impact of major transition on management effectiveness.

Effect of the Bullying: The Power to Cope Program on Children's Response to Bullying

2015 ◽  
Vol 6 ◽  
Author(s):  
Zoe Markopoulos ◽  
Michael E. Bernard
Keyword(s):  
Intervention Program ◽  
Self Report ◽  
Future Research ◽  
Control Group ◽  
Behaviour Therapy ◽  
Coping Responses ◽  
Emotional Coping ◽  
Self Report Data ◽  
Children's Coping ◽  
Experimental Group

This study evaluated the Bullying: The Power to Cope program (Bernard, 2012), which is designed to teach children the ideas espoused in the practice of rational emotive behaviour therapy (REBT) to employ in response to bullying. Self-report data were collected at pre- and post-test of children's cognitive, behavioural, and emotional coping responses to four written bullying vignettes. At pre-test, children's personal qualities of intrinsic resiliency were also measured. The sample consisted of 139 participants in Melbourne, Australia (n = 80 in the experimental group and n = 59 in the control group), aged from 10 to 14 years. Results indicated children in the experimental group improved in cognitive and emotional coping responses relative to children in the control group. Females showed greater improvement than males in coping responses to bullying as a consequence of the intervention. Entering levels of intrinsic resiliency did not moderate the effects of the intervention program on children's coping responses. The cognitive and emotional coping responses of females to bullying vignettes (pre-test) were significantly more negative and emotionally intense than males. The implications of these findings are discussed, as well as limitations and directions for future research.

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