Brain Activity Elicited by Emotional Stimuli During a Verbal Working Memory Task: A Comparison of Healthy Adults and Patients with Chronic Schizophrenia

NeuroImage ◽  
2009 ◽  
Vol 47 ◽  
pp. S166
Author(s):  
MT Diaz ◽  
G He ◽  
S Gadde ◽  
C Bellion ◽  
A Belger ◽  
...  
Keyword(s):  
Working Memory ◽  
Brain Activity ◽  
Memory Task ◽  
Verbal Working Memory ◽  
Chronic Schizophrenia ◽  
Healthy Adults ◽  
Emotional Stimuli

scholarly journals Modafinil modulates anterior cingulate function in chronic schizophrenia

2005 ◽  
Vol 187 (1) ◽  
pp. 55-61 ◽  
Author(s):  
Sean A. Spence ◽  
Russell D. Green ◽  
Iain D. Wilkinson ◽  
Mike D. Hunter
Keyword(s):  
Working Memory ◽  
Anterior Cingulate Cortex ◽  
Cognitive Performance ◽  
Cognitive Deficits ◽  
Brain Activity ◽  
Memory Task ◽  
Cingulate Cortex ◽  
Chronic Schizophrenia ◽  
Anterior Cingulate ◽  
Double Blind

BackgroundSchizophrenia is associated with widespread cognitive deficits that have an impact on social function. Modafinil promotes wakefulness and is reported to enhance cognition.AimsTo study the acute effects of modafinil administration upon brain activity and cognitive performance in people with chronic schizophrenia.MethodIn a randomised double-blind placebo-controlled crossover design, 19 patients received either modafinil (100 mg) or placebo prior to undertaking a working memory task with functional magnetic resonance imaging.ResultsSeventeen patients completed the study and another underwent acute relapse 4 days post-drug. Modafinil administration was associated with significantly greater activation in the anterior cingulate cortex during the working memory task. The anterior cingulate cortex signal correlated with cognitive performance, although only a subset of patients exhibited ‘enhancement’.ConclusionsModafinil modulates anterior cingulate cortex function in chronic schizophrenia but its beneficial cognitive effects may be restricted to a subset of patients requiring further characterisation.

scholarly journals Brain hemodynamic response in Examiner–Examinee dyads during spatial short-term memory task: an fNIRS study

2021 ◽  
Author(s):  
Francesco Panico ◽  
Stefania De Marco ◽  
Laura Sagliano ◽  
Francesca D’Olimpio ◽  
Dario Grossi ◽  
...  
Keyword(s):  
Working Memory ◽  
Cognitive Processes ◽  
Short Term Memory ◽  
Spatial Working Memory ◽  
Brain Activity ◽  
Memory Task ◽  
Neural Correlates ◽  
Short Term ◽  
Term Memory ◽  
The Real

AbstractThe Corsi Block-Tapping test (CBT) is a measure of spatial working memory (WM) in clinical practice, requiring an examinee to reproduce sequences of cubes tapped by an examiner. CBT implies complementary behaviors in the examiners and the examinees, as they have to attend a precise turn taking. Previous studies demonstrated that the Prefrontal Cortex (PFC) is activated during CBT, but scarce evidence is available on the neural correlates of CBT in the real setting. We assessed PFC activity in dyads of examiner–examinee participants while completing the real version of CBT, during conditions of increasing and exceeding workload. This procedure allowed to investigate whether brain activity in the dyads is coordinated. Results in the examinees showed that PFC activity was higher when the workload approached or reached participants’ spatial WM span, and lower during workload conditions that were largely below or above their span. Interestingly, findings in the examiners paralleled the ones in the examinees, as examiners’ brain activity increased and decreased in a similar way as the examinees’ one. In the examiners, higher left-hemisphere activity was observed suggesting the likely activation of non-spatial WM processes. Data support a bell-shaped relationship between cognitive load and brain activity, and provide original insights on the cognitive processes activated in the examiner during CBT.

scholarly journals Treatment effects on brain activity during a working memory task in obstructive sleep apnea

2009 ◽  
Vol 18 (4) ◽  
pp. 404-410 ◽  
Author(s):  
MARK S. ALOIA ◽  
LAWRENCE H. SWEET ◽  
BETH A. JERSKEY ◽  
MOLLY ZIMMERMAN ◽  
JOHN TODD ARNEDT ◽  
...  
Keyword(s):  
Working Memory ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Treatment Effects ◽  
Brain Activity ◽  
Memory Task ◽  
Obstructive Sleep

208 – A simultaneous fMRI and EEG investigation of coordination of brain activity during a working memory task in schizophrenia

2008 ◽  
Vol 98 ◽  
pp. 119
Author(s):  
P.K. Mallikarjun ◽  
A. Diukova ◽  
J. Cahill ◽  
D. Auer ◽  
P.F. Liddle
Keyword(s):  
Working Memory ◽  
Brain Activity ◽  
Memory Task

Verbal Working Memory Task

1996 ◽  
Author(s):  
Alexandra Gottardo ◽  
Keith E. Stanovich ◽  
Linda S. Siegel
Keyword(s):  
Working Memory ◽  
Memory Task ◽  
Verbal Working Memory

scholarly journals Dopamine transporter genotype modulates brain activity during a working memory task in children with ADHD

2019 ◽  
Vol 92 ◽  
pp. 103430 ◽  
Author(s):  
Guillaume Pineau ◽  
Thomas Villemonteix ◽  
Hichem Slama ◽  
Martin Kavec ◽  
Danielle Balériaux ◽  
...  
Keyword(s):  
Working Memory ◽  
Dopamine Transporter ◽  
Brain Activity ◽  
Memory Task ◽  
Children With Adhd

Effects of Aquatic Motor Intervention on Verbal Working Memory and Brain Activity-A Pilot Study

2018 ◽  
Vol 12 (2) ◽  
pp. 90-99 ◽  
Author(s):  
Michal Nissim ◽  
Ronit Ram-Tsur ◽  
Joseph Glicksohn ◽  
Michal Zion ◽  
Zemira Mevarech ◽  
...  
Keyword(s):  
Working Memory ◽  
Pilot Study ◽  
Brain Activity ◽  
Verbal Working Memory

Examining Positivity Effect and Working Memory in Young-Old and Very Old Adults Using EEG-Derived Cognitive State Metrics

2019 ◽  
Vol 41 (10) ◽  
pp. 1014-1035
Author(s):  
Joelle C. Ruthig ◽  
Dmitri P. Poltavski ◽  
Thomas Petros
Keyword(s):  
Older Adults ◽  
Working Memory ◽  
Memory Task ◽  
Cognitive State ◽  
Emotional Stimuli ◽  
Very Old ◽  
Positivity Effect ◽  
Old Adults ◽  
Age Related ◽  
Young Old

The positivity effect among older adults is a tendency to process more positive and/or less negative emotional stimuli compared to younger adults, with unknown upper age boundaries. Cognitive and emotional working memory were assessed in young-old adults (60–75) and very old adults (VOAs; 80+) to determine whether emotional working memory declines similar to the age-related decline of cognitive working memory. The moderating role of valence on the link between age and emotional working memory was examined to identify change in positivity effect with advanced age. Electroencephalography (EEG) markers of cognitive workload and engagement were obtained to test the theory of cognitive resource allocation in older adults’ emotional stimuli processing. EEG recordings were collected during cognitive memory task and emotional working memory tasks that required rating emotional intensity of images pairs. Results indicate a positivity effect among VOAs that does not require additional cognitive effort and is not likely to diminish with age.

Comparison of diffusion-weighted fMRI and BOLD fMRI responses in a verbal working memory task

NeuroImage ◽  
2013 ◽  
Vol 67 ◽  
pp. 25-32 ◽  
Author(s):  
Toshihiko Aso ◽  
Shin-ichi Urayama ◽  
Hidenao Fukuyama ◽  
Denis Le Bihan
Keyword(s):  
Working Memory ◽  
Memory Task ◽  
Verbal Working Memory ◽  
Bold Fmri ◽  
Diffusion Weighted

The functional neuroanatomy of schizophrenic subsyndromes

2003 ◽  
Vol 33 (6) ◽  
pp. 1007-1018 ◽  
Author(s):  
G. D. HONEY ◽  
T. SHARMA ◽  
J. SUCKLING ◽  
V. GIAMPIETRO ◽  
W. SONI ◽  
...  
Keyword(s):  
Working Memory ◽  
Factor Analysis ◽  
Rating Scale ◽  
Premotor Cortex ◽  
Cognitive Activity ◽  
Memory Task ◽  
Verbal Working Memory ◽  
Functional Neuroanatomy ◽  
Diverse Range ◽  
Negatively Associated

Background. There is considerable variability between patients in their expression of the diverse range of symptoms encompassed by the syndrome of schizophrenia, which may modulate functional activation to cognitive processing.Method. Here we investigate associations between schizophrenic subsyndrome scores, identified by factor analysis, and experimentally controlled brain activation. Five factors were defined by rotated principal components analysis of PANSS rating scale measurements in 100 patients with schizophrenia. A subsample of 30 patients and a group of 27 comparison subjects were studied using functional magnetic resonance imaging (fMRI) during the performance of two periodically designed cognitive activation experiments: verbal working memory and psychomotor sequencing.Results. Factor analysis replicated the five dimensions consistently reported. Within the patient group, power of activation by working memory was negatively associated with global symptom severity in left lingual and temporo-parietal cortices; negatively associated with positive subsyndrome scores in left inferior frontal and superior temporal cortices and basal ganglia; and positively associated with negative subsyndrome scores in lateral and medial premotor cortex. No relationship was observed between subsyndrome scores and functional activation during the motor task. Between-group comparisons demonstrated reduced power of response to the working memory task by patients in bilateral dorsolateral prefrontal and left pre- and post-central cortices.Conclusions. In this study we observed task-specific modulation of functional response associated with symptom expression in schizophrenia. Our findings are compatible with previous empirical findings and theoretical conceptualization of human brain function, in terms of capacity constraints on activation in the face of competing demands from pathological and task-related cognitive activity.

Sign in / Sign up

Export Citation Format

Share Document